The activity of a PI3K δ-sparing inhibitor, MEN1611, in non-small cell lung cancer cells with constitutive activation of the PI3K/AKT/mTOR pathway.

Autor: Papoff G; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Presutti D; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Fustaino V; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Parente A; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Calandriello C; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Alemà S; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy., Scavizzi F; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy.; European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic, IBBC-CNR, Monterotondo, Rome, Italy., Raspa M; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy.; European Mouse Mutant Archive (EMMA), INFRAFRONTIER, Monterotondo Mouse Clinic, IBBC-CNR, Monterotondo, Rome, Italy., Merlino G; Menarini Ricerche S.p.A., Rome, Italy., Salerno M; Menarini Ricerche S.p.A., Rome, Italy., Bigioni M; Menarini Ricerche S.p.A., Rome, Italy., Binaschi M; Menarini Ricerche S.p.A., Rome, Italy., Ruberti G; Institute of Biochemistry and Cell Biology, National Research Council (IBBC-CNR), Monterotondo, Rome, Italy.

Publikováno v: Frontiers in oncology [Front Oncol] 2023 Nov 14; Vol. 13, pp. 1283951. Date of Electronic Publication: 2023 Nov 14 (Print Publication: 2023).

Combining rotary wet-spinning biofabrication and electro-mechanical stimulation for the in vitro production of functional myo-substitutes.

Autor: Celikkin N; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland., Presutti D; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland., Maiullari F; Istituto Nazionale Genetica Molecolare INGM 'Romeo ed Enrica Invernizzi', Milan, Italy.; PhD Program in Cellular and Molecular Biology, Department of Biology, University of Rome Tor Vergata, Rome, Italy., Volpi M; Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland., Promovych Y; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland., Gizynski K; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland., Dolinska J; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland., Wiśniewska A; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland., Opałło M; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland., Paradiso A; Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland., Rinoldi C; Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland., Fuoco C; Department of Biology, University of Rome, Tor Vergata, Rome, Italy., Swieszkowski W; Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland., Bearzi C; Istituto Nazionale Genetica Molecolare INGM 'Romeo ed Enrica Invernizzi', Milan, Italy.; Department of Medical Surgical Sciences and Biotechnologies, Sapienza University of Rome, C.so della Repubblica 79, 04100 Latina, Rome, Italy.; Institute of Biomedical Technologies, National Research Council of Italy (ITB-CNR), Segrate, Milan, Italy., Rizzi R; Istituto Nazionale Genetica Molecolare INGM 'Romeo ed Enrica Invernizzi', Milan, Italy.; Department of Medical Surgical Sciences and Biotechnologies, Sapienza University of Rome, C.so della Repubblica 79, 04100 Latina, Rome, Italy.; Institute of Biomedical Technologies, National Research Council of Italy (ITB-CNR), Segrate, Milan, Italy., Gargioli C; Department of Biology, University of Rome, Tor Vergata, Rome, Italy., Costantini M; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland.

Publikováno v: Biofabrication [Biofabrication] 2023 Aug 09; Vol. 15 (4). Date of Electronic Publication: 2023 Aug 09.

In Vitro and In Vivo Effects of the Urokinase Plasminogen Activator Inhibitor WX-340 on Anaplastic Thyroid Cancer Cell Lines.

Autor: Baldini E; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Presutti D; Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Monterotondo, 00015 Rome, Italy., Favoriti P; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Santini S; Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Monterotondo, 00015 Rome, Italy., Papoff G; Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Monterotondo, 00015 Rome, Italy., Tuccilli C; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Carletti R; Department of Radiological, Oncological and Pathological Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Di Gioia C; Department of Radiological, Oncological and Pathological Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Lori E; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Ferent IC; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Gagliardi F; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Catania A; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Pironi D; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Tripodi D; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., D'Andrea V; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Sorrenti S; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy., Ruberti G; Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Monterotondo, 00015 Rome, Italy., Ulisse S; Department of Surgical Sciences, 'Sapienza' University of Rome, 00161 Rome, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 28; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 28.

Tackling Current Biomedical Challenges With Frontier Biofabrication and Organ-On-A-Chip Technologies.

Autor: Celikkin N; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland., Presutti D; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland., Maiullari F; Istituto Nazionale Genetica Molecolare INGM 'Romeo Ed Enrica Invernizzi', Milan, Italy., Fornetti E; Department of Biology, Rome University Tor Vergata, Rome, Italy., Agarwal T; Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur, India., Paradiso A; Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland., Volpi M; Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland., Święszkowski W; Faculty of Materials Science and Engineering, Warsaw University of Technology, Warsaw, Poland., Bearzi C; Istituto Nazionale Genetica Molecolare INGM 'Romeo Ed Enrica Invernizzi', Milan, Italy.; Institute of Genetic and Biomedical Research, National Research Council of Italy (IRGB-CNR), Milan, Italy., Barbetta A; Department of Chemistry, Sapienza University of Rome, Rome, Italy., Zhang YS; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Cambridge, MA, United States., Gargioli C; Department of Biology, Rome University Tor Vergata, Rome, Italy., Rizzi R; Istituto Nazionale Genetica Molecolare INGM 'Romeo Ed Enrica Invernizzi', Milan, Italy.; Institute of Genetic and Biomedical Research, National Research Council of Italy (IRGB-CNR), Milan, Italy.; Institute of Biomedical Technologies, National Research Council of Italy (ITB-CNR), Milan, Italy., Costantini M; Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland.

Publikováno v: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2021 Sep 16; Vol. 9, pp. 732130. Date of Electronic Publication: 2021 Sep 16 (Print Publication: 2021).

Integrated analysis of DNA copy number and gene expression data in Lung Cancer models of resistance to targeted therapy

Autor: Fustaino V(1, Presutti D(1), Cardinali B(1), Colombo T(3), Papoff G(1), Santini S(1), Lalli C(1), Giannini G(4), Brandi R(5), Arisi I(5), D'Onofrio M(5), Felici G(2), Ruberti G(1)

Publikováno v: BITS Annual Meeting, Roma, 26-28 Febbraio 2014
info:cnr-pdr/source/autori:Fustaino V(1,2), Presutti D(1), Cardinali B(1), Colombo T(3), Papoff G(1), Santini S(1), Lalli C(1), Giannini G(4), Brandi R(5), Arisi I(5), D'Onofrio M(5), Felici G(2) and Ruberti G(1)/congresso_nome:BITS Annual Meeting/congresso_luogo:Roma/congresso_data:26-28 Febbraio 2014/anno:2014/pagina_da:/pagina_a:/intervallo_pagine

Motivation: Tyrosine Kinase inhibitors (TKIs) constitute the most promising frontier of the last decade in the field of cancer treatment. However, the development of resistance mechanisms often makes the tumour insensitive to TKI-targeted therapy. Id

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::785406880a92dcfb33e4c34f9d0a6955
https://publications.cnr.it/doc/287458