Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Preston Countryman"'
Autor:
Saroj Dangi, Ming Liu, Zubair Azad, Preston Countryman, Maedeh Roushan, Gideon I. Livshits, Parminder Kaur, Hai Pan, Zhubing Shi, Ariana C. Detwiler, Patricia L. Opresko, Hongtao Yu, Hong Wang, Robert Riehn
Single-molecule techniques provide important details supplementing the framework obtained from traditional bulk experiments. Many cellular processes such as DNA replication, DNA repair, and telomere maintenance involve interaction among multiple prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e085b61e38dbe544779919497b3f5a73
https://doi.org/10.1101/2022.12.29.521498
https://doi.org/10.1101/2022.12.29.521498
Autor:
Parminder Kaur, Matthew J. Longley, Hong Wang, Hai Pan, William C. Copeland, Preston Countryman, Wendy Wang
Publikováno v:
J Biol Chem
Knowledge of the molecular events in mitochondrial DNA (mtDNA) replication is crucial to understanding the origins of human disorders arising from mitochondrial dysfunction. Twinkle helicase is an essential component of mtDNA replication. Here, we em
Autor:
Xiao-Ying Lei, Jiangguo Lin, Preston Countryman, Robert Riehn, Yanlin Fan, Alexander J.R. Bishop, Yizhi Jane Tao, Hong Wang, Xuechun Wang, Christian White, Aparna Gorthi, Jacob Piehler, Changjiang You, Jack Strickland, Ingrid Tessmer, Nicolas Wirth, Parminder Kaur, Hai Pan
Publikováno v:
Journal of Biological Chemistry. 293:1054-1069
Proper chromosome alignment and segregation during mitosis depend on cohesion between sister chromatids, mediated by the cohesin protein complex, which also plays crucial roles in diverse genome maintenance pathways. Current models attribute DNA bind
Autor:
Wang Miao, Yizhi Jane Tao, Yunyun Jiang, Hong Wang, Jacob Piehler, Gisele Gurgel, Parminder Kaur, Patricia L. Opresko, Preston Countryman, Susan Smith, Yanlin Fan, Jiangguo Lin, Hai Pan, Robert Riehn, Haijiang Chen, Changjiang You, Neil M. Kad
Publikováno v:
Nucleic Acids Research
Proper chromosome alignment and segregation during mitosis depend on cohesion between sister chromatids. Cohesion is thought to occur through the entrapment of DNA within the tripartite ring (Smc1, Smc3 and Rad21) with enforcement from a fourth subun
Publikováno v:
DNA Repair. 20:142-153
Telomeres play important roles in maintaining the stability of linear chromosomes. Telomere maintenance involves dynamic actions of multiple proteins interacting with long repetitive sequences and complex dynamic DNA structures, such as G-quadruplexe
Autor:
Simon C. Watkins, Hong Wang, Yiyun Zhang, Greg Gibson, Patricia L. Opresko, Jiangguo Lin, Neil M. Kad, Parminder Kaur, Changjiang You, Noah Buncher, Preston Countryman, Jacob Piehler, Longjiang E
Publikováno v:
Nucleic Acids Research
Human telomeres are maintained by the shelterin protein complex in which TRF1 and TRF2 bind directly to duplex telomeric DNA. How these proteins find telomeric sequences among a genome of billions of base pairs and how they find protein partners to f
Autor:
Jiangguo Lin, Preston Countryman, Hong Wang, Parminder Kaur, Kira C. Bradford, Dorothy A. Erie, Robert Riehn, Patricia L. Opresko, Dong Wu
Publikováno v:
Scientific Reports
Shelterin protein TRF2 modulates telomere structures by promoting dsDNA compaction and T-loop formation. Advancement of our understanding of the mechanism underlying TRF2-mediated DNA compaction requires additional information regarding DNA paths in
Autor:
Yizhi Jane Tao, Jiangguo Lin, Parminder Kaur, Preston Countryman, Hong Wang, Edward Brennan, Changjiang You, Haijiang Chen, Jacob Piehler
Publikováno v:
Biophysical Journal. 108(2)
Cohesin is a multi-protein complex involved in sister chromatid cohesion during cell replication and double strand DNA break repair. Cohesin core complex consists of a ring-like trimer and either SA1 or SA2 in somatic vertebrate cells. While SA1 and
Autor:
Robert Riehn, Shuang Fang Lim, Carlos Ortiz, Preston Countryman, Maedeh Roushan, Hong Wang, Alena Karpusenko, Parminder Kaur
Publikováno v:
Biomicrofluidics. 8(3)
We present an analytic technique for probing protein-catalyzed transient DNA loops that is based on nanofluidic channels. In these nanochannels, DNA is forced in a linear configuration that makes loops appear as folds whose size can easily be quantif
Autor:
Jiangguo Lin, Parminder Kaur, Preston Countryman, Hong Wang, Susan Smith, Patricia L. Opresko, Jane Tao
Publikováno v:
Biophysical Journal. 108:7a
Telomeres play important roles in maintaining the stability of linear chromosomes. A specialized protein complex, called shelterin or telosome, binds to and protects telomeres at chromosome ends. Telomere maintenance involves dynamic actions of multi