Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Preston, Leung"'
Autor:
Sara Bohnstedt Mørup, Preston Leung, Cavan Reilly, Brad T. Sherman, Weizhong Chang, Maja Milojevic, Ana Milinkovic, Angelike Liappis, Line Borgwardt, Kathy Petoumenos, Roger Paredes, Shweta S. Mistry, Cameron R. MacPherson, Jens Lundgren, Marie Helleberg, Joanne Reekie, Daniel D. Murray, for the INSIGHT FIRST and START study groups
Publikováno v:
AIDS Research and Therapy, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Background Human genetic contribution to HIV progression remains inadequately explained. The type 1 interferon (IFN) pathway is important for host control of HIV and variation in type 1 IFN genes may contribute to disease progression. This s
Externí odkaz:
https://doaj.org/article/8aa261a5c95940b6ad7f4516bcd362c8
Autor:
Quenia dos Santos, Preston Leung, Christian W. Thorball, Bruno Ledergerber, Jacques Fellay, Cameron R. MacPherson, Mads Hornum, Cynthia Terrones-Campos, Allan Rasmussen, Finn Gustafsson, Michael Perch, Søren S. Sørensen, Christina Ekenberg, Jens D. Lundgren, Bo Feldt‐Rasmussen, Joanne Reekie
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Type 2 diabetes mellitus (T2DM) can be multifactorial where both genetics and environmental factors play a role. We aimed to investigate the use of polygenic risk scores (PRS) in the prediction of pre-transplant T2DM and post-transplant diabetes mell
Externí odkaz:
https://doaj.org/article/d0c41004cf38431ba537696192722e93
Autor:
Curtis Cai, Jerome Samir, Mehdi R. Pirozyan, Thiruni N. Adikari, Money Gupta, Preston Leung, Brendan Hughes, Willem Van der Byl, Simone Rizzetto, Auda Elthala, Elizabeth Keoshkerian, Jean-Louis Palgen, Timothy Peters, Thi H. O. Nguyen, Raymond Louie, Katherine Kedzierska, Silvana Gaudieri, Rowena A. Bull, Andrew R. Lloyd, Fabio Luciani
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The early immune response following exposure to HCV is not fully explored. Here the authors use single cell analysis and immune profiling to relate the infection sequence and immune response to early HCV infection showing that exhausted phenotypes of
Externí odkaz:
https://doaj.org/article/588f772ffcbf4737b2226e6c72bd6b81
Autor:
Ramtin Zargari Marandi, Preston Leung, Chathurani Sigera, Daniel Dawson Murray, Praveen Weeratunga, Deepika Fernando, Chaturaka Rodrigo, Senaka Rajapakse, Cameron Ross MacPherson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 3, p e0010758 (2023)
BackgroundAt least a third of dengue patients develop plasma leakage with increased risk of life-threatening complications. Predicting plasma leakage using laboratory parameters obtained in early infection as means of triaging patients for hospital a
Externí odkaz:
https://doaj.org/article/2f6ace7c13724425818e57d6c7ba35d8
Autor:
Nasir Riaz, Preston Leung, Kirston Barton, Martin A. Smith, Shaun Carswell, Rowena Bull, Andrew R. Lloyd, Chaturaka Rodrigo
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Hepatitis C (HCV) and many other RNA viruses exist as rapidly mutating quasi-species populations in a single infected host. High throughput characterization of full genome, within-host variants is still not possible despite advanc
Externí odkaz:
https://doaj.org/article/27ac5a45c50a4b9891f2a9cec58eaa4c
Autor:
Thiruni N. Adikari, Francesca Di Giallonardo, Preston Leung, Alba Grifoni, Alex Sette, Daniela Weiskopf, Rowena A. Bull, Fabio Luciani
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Cytotoxic CD8+ T cells are key for immune protection against viral infections. The breadth and cross-reactivity of these responses are important against rapidly mutating RNA viruses, such as dengue (DENV), yet how viral diversity affect T ce
Externí odkaz:
https://doaj.org/article/51745d141be148b08de2cd69f032174f
Autor:
Adrian G. Zucco, Marc Bennedbæk, Christina Ekenberg, Migle Gabrielaite, Preston Leung, Mark N. Polizzotto, Virginia Kan, Daniel D. Murray, Jens D. Lundgren, Cameron R. Macpherson
Publikováno v:
AIDS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62edb7b2512cf1de33c8363198c29050
https://doi.org/10.1097/qad.0000000000003557
https://doi.org/10.1097/qad.0000000000003557
Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring
Autor:
Neil A Youngson, Virginie Lecomte, Christopher A Maloney, Preston Leung, Jia Liu, Luke B Hesson, Fabio Luciani, Lutz Krause, Margaret J Morris
Publikováno v:
Asian Journal of Andrology, Vol 18, Iss 6, Pp 930-936 (2016)
There is now strong evidence that the paternal contribution to offspring phenotype at fertilisation is more than just DNA. However, the identity and mechanisms of this nongenetic inheritance are poorly understood. One of the more important questions
Externí odkaz:
https://doaj.org/article/0ed6e12b3ceb408b94b78873d07da818
Autor:
Daniel D. Murray, Birgit Grund, Cameron R. MacPherson, Christina Ekenberg, Adrian G. Zucco, Joanne Reekie, Lourdes Dominguez-Dominguez, Preston Leung, Dahlene Fusco, Julien Gras, Jan Gerstoft, Marie Helleberg, Álvaro H. Borges, Mark N. Polizzotto, Jens D. Lundgren
Publikováno v:
Murray, D D, Grund, B, Macpherson, C R, Ekenberg, C, Zucco, A G, Reekie, J, Dominguez-Dominguez, L, Leung, P, Fusco, D, Gras, J, Gerstoft, J, Helleberg, M, Borges, Á H, Polizzotto, M N & Lundgren, J D 2023, ' Association between ten-eleven methylcytosine dioxygenase 2 genetic variation and viral load in people with HIV ', AIDS, vol. 37, no. 3, pp. 379-387 . https://doi.org/10.1097/QAD.0000000000003427
Introduction:Identifying genetic factors that influence HIV-pathogenesis is critical for understanding disease pathways. Previous studies have suggested a role for the human gene ten-eleven methylcytosine dioxygenase 2 (TET2) in modulating HIV-pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b5b50e2d72d6a0411ea9f4545e2dec
https://curis.ku.dk/portal/da/publications/association-between-teneleven-methylcytosine-dioxygenase-2-genetic-variation-and-viral-load-in-people-with-hiv(a9044e18-952b-4359-af38-2036ff34020a).html
https://curis.ku.dk/portal/da/publications/association-between-teneleven-methylcytosine-dioxygenase-2-genetic-variation-and-viral-load-in-people-with-hiv(a9044e18-952b-4359-af38-2036ff34020a).html
Autor:
Daniel D, Murray, Birgit, Grund, Cameron, MacPherson, Christina, Ekenberg, Adrian, Zucco, Joanne, Reekie, Lourdes, Dominguez-Dominguez, Preston, Leung, Dahlene, Fusco, Julien, Gras, Jan, Gerstoft, Marie, Helleberg, Álvaro H, Borges, Mark, Polizzotto, Jens D, Lundgren
Publikováno v:
AIDS (London, England).
Identifying genetic factors that influence HIV-pathogenesis is critical for understanding disease pathways. Previous studies have suggested a role for the human gene ten-eleven methylcytosine dioxygenase 2 (TET2) in modulating HIV-pathogenesis.We ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d327082c4b86c912c902b0aa3f7266d
https://pubmed.ncbi.nlm.nih.gov/36473831
https://pubmed.ncbi.nlm.nih.gov/36473831