Zobrazeno 1 - 10
of 11 595
pro vyhledávání: '"Pressure Overload"'
Autor:
Matteo Sorge, Giulia Savoré, Andrea Gallo, Davide Acquarone, Mauro Sbroggiò, Silvia Velasco, Federica Zamporlini, Saveria Femminò, Enrico Moiso, Giampaolo Morciano, Elisa Balmas, Andrea Raimondi, Gabrielle Nattenberg, Rachele Stefania, Carlo Tacchetti, Angela Maria Rizzo, Paola Corsetto, Alessandra Ghigo, Emilia Turco, Fiorella Altruda, Lorenzo Silengo, Paolo Pinton, Nadia Raffaelli, Nathan J Sniadecki, Claudia Penna, Pasquale Pagliaro, Emilio Hirsch, Chiara Riganti, Guido Tarone, Alessandro Bertero, Mara Brancaccio
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2450-2484 (2024)
Abstract Defining the molecular mechanisms underlying cardiac resilience is crucial to find effective approaches to protect the heart. A physiologic level of ROS is produced in the heart by fatty acid oxidation, but stressful events can boost ROS and
Externí odkaz:
https://doaj.org/article/fbbe12027f6940b5871e50bcfc957a2f
Autor:
Maelle Cherpaz, Emmanuelle Meugnier, Gaultier Seillier, Matteo Pozzi, Romain Pierrard, Simon Leboube, Fadi Farhat, Marco Vola, Jean-François Obadia, Camille Amaz, Lara Chalabreysse, Chloe May, Stephanie Chanon, Camille Brun, Lucas Givre, Gabriel Bidaux, Nathan Mewton, Genevieve Derumeaux, Cyrille Bergerot, Melanie Paillard, Helene Thibault
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-18 (2024)
Abstract Background Type 2 diabetes (T2D) is a frequent comorbidity encountered in patients with severe aortic stenosis (AS), leading to an adverse left ventricular (LV) remodeling and dysfunction. Metabolic alterations have been suggested as contrib
Externí odkaz:
https://doaj.org/article/c6ea5e7b71e846228277dfae2c1f6106
Autor:
Zihui Zheng, Mengmeng Zhao, Yao Xu, Jishou Zhang, Shanshan Peng, Jianfang Liu, Wei Pan, Zheng Yin, Cheng Wei, Juan-Juan Qin, Jun Wan, Menglong Wang
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 12, Pp 100679- (2024)
Accumulating evidence has revealed that chronic unresolved inflammation can cause significant tissue damage and can be a key mediator of advanced heart failure (HF). Resolvin (Rv) D2, a member of specialized pro-resolving lipid mediators (SPMs), play
Externí odkaz:
https://doaj.org/article/922331dc3ebf446d95f4ea6422e540ff
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
Heart failure, a leading driver of global mortality, remains a topic of intense contemporary research interest due to the prevailing unmet need in cardiometabolic therapeutics. Numerous mechanisms with the potential to influence the onset and develop
Externí odkaz:
https://doaj.org/article/7924a5ec7a0b46bf9182d15a49b41aa3
Autor:
Umesh Bhattarai, Rui Xu, Xiaochen He, Lihong Pan, Ziru Niu, Dongzhi Wang, Heng Zeng, Jian-Xiong Chen, John S. Clemmer, Yingjie Chen
Publikováno v:
Redox Biology, Vol 76, Iss , Pp 103325- (2024)
Selenium (Se) deficiency is associated with the development of Keshan disease, a cardiomyopathy associated with massive cardiac immune cell infiltration that can lead to heart failure (HF). The purpose of this study was to determine whether high Se d
Externí odkaz:
https://doaj.org/article/bfdb56c22ffa4f6abe32a0eca6ee3975
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Pathological cardiac hypertrophy is an important cause of heart failure(HF). Recent studies reveal that glucagon-like peptide-1 receptor (GLP1R) agonists can improve mortality and left ventricular ejection fraction in the patients with type
Externí odkaz:
https://doaj.org/article/02c15e29eaf8411a80cc704035341fcc
Autor:
Zheng, Zihui 1, 2, 3, ‡, Zhao, Mengmeng 1, 2, 3, ‡, Xu, Yao 1, 2, 3, ‡, Zhang, Jishou 1, 2, 3, Peng, Shanshan 1, 2, 3, Liu, Jianfang 1, 2, 3, Pan, Wei 1, 2, 3, Yin, Zheng 1, 2, 3, Wei, Cheng 1, 2, 3, Qin, Juan-Juan 4, 5, ∗, Wan, Jun 1, 2, 3, ∗, Wang, Menglong 1, 2, 3, ∗
Publikováno v:
In Journal of Lipid Research December 2024 65(12)
Autor:
Pan, Le a, 1, Huang, Chenxing a, 1, Jin, Xuejuan a, 1, Wu, Jian a, b, Jin, Kejia a, Lin, Jingyi a, Wang, Ying a, Li, Jianxuan a, Yin, Chao a, Wang, Xiang a, Zhang, Lei a, Zhang, Guoping a, Dong, Hangming c, Guo, Junli d, Komuro, Issei e, Dai, Yuxiang a, b, ⁎⁎, Zou, Yunzeng a, b, ⁎⁎⁎, Gong, Hui a, b, ⁎
Publikováno v:
In Redox Biology February 2025 79
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Heart failure with preserved ejection fraction (HFpEF) is a multifaceted pathogenesis disease and the exact mechanisms driving HFpEF have not been completely elucidated. Pressure overload hypertrophy (POH) related fibroblasts and M2 macrophages in HF
Externí odkaz:
https://doaj.org/article/ed15390752ec43ce96c13322f570427c