Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Presley L Cannon"'
Autor:
Chitra Basu, Presley L. Cannon, Cassandra P. Awgulewitsch, Cristi L. Galindo, Eric R. Gamazon, Antonis K. Hatzopoulos
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Endothelial cells (ECs) have essential roles in cardiac tissue repair after myocardial infarction (MI). To establish stage-specific and long-term effects of the ischemic injury on cardiac ECs, we analyzed their transcriptome at landmark time
Externí odkaz:
https://doaj.org/article/c3e8379179da4c26b3e3f27a328ac2b4
The BDNF rs6265 Polymorphism is a Modifier of Cardiomyocyte Contractility and Dilated Cardiomyopathy
Autor:
Jonathan H. Soslow, Frank J. Raucci, Larry W Markham, Hind Lal, Lin Zhong, Antonis K. Hatzopoulos, Maciej S. Buchowski, Presley L. Cannon, Natasja Lessiohadi, William B. Burnette, Erica J. Carrier, Anand Prakash Singh, Cassandra P. Awgulewitsch, Qinkun Zhang, Joseph T. Roland, Prachi Umbarkar, Wejdan Aljafar, Cristi L. Galindo
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7466, p 7466 (2020)
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7466, p 7466 (2020)
Brain-derived neurotrophic factor (BDNF) is a neuronal growth and survival factor that harbors cardioprotective qualities that may attenuate dilated cardiomyopathy. In ~30% of the population, BDNF has a common, nonsynonymous single nucleotide polymor
Autor:
Courtney Cates, Abdullah Kaplan, Andriy Yabluchanskiy, Kristine Y. DeLeon-Pennell, Merry L. Lindsey, Lisandra E. de Castro Brás, Ganesh V. Halade, Rogelio Zamilpa, Presley L. Cannon, Rugmani Padmanabhan Iyer, Elizabeth R. Flynn, Yonggang Ma, Ying Ann Chiao
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 315:H522-H530
The generation of big data has enabled systems-level dissections into the mechanisms of cardiovascular pathology. Integration of genetic, proteomic, and pathophysiological variables across platforms and laboratories fosters discoveries through multid
Autor:
Presley L. Cannon, Merry L. Lindsey, Kristine Y. DeLeon-Pennell, Courtney L Harrison, Michael E. Hall, Mira Jung, Crystal M. Ripplinger, Yonggang Ma, Elizabeth R. Flynn, Fritz M. Valerio, Rugmani Padmanabhan Iyer, Andriy Yabluchanskiy
Publikováno v:
Cardiovascular Research. 115:395-408
AIMS: Macrophage phagocytosis of dead cells is a prerequisite for inflammation resolution. Because CXCL4 induces macrophage phagocytosis in vitro, we examined the impact of exogenous CXCL4 infusion on cardiac wound healing and macrophage phagocytosis
Autor:
Merry L. Lindsey, Rugmani Padmanabhan Iyer, Andriy Yabluchanskiy, Presley L. Cannon, Hiroe Toba, Jeanine D'Armiento
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 312:H375-H383
Advancing age is an independent risk factor for cardiovascular disease. Matrix metalloproteinase-9 (MMP-9) is secreted by macrophages and robustly increases in the left ventricle (LV) with age. The present study investigated the effect of MMP-9 overe
Autor:
Lin Zhong, Frank J Raucci, Jonathan H. Soslow, Wejdan Aljafar, Presley L Cannon, Cristi L. Galindo, Cassandra P. Awgulewitsch, Hind Lal, Erica J. Carrier, Anand P Singh, Antonis K. Hatzopoulos, Prachi Umbarkar, Natasja Lessiohadi, Holly M. Smith, Qinkun Zhang
Publikováno v:
Circulation Research. 125
We previously identified brain-derived neurotrophic factor (BDNF) as a putative cardiac-specific biomarker for preserved cardiac function in Duchenne Muscular Dystrophy (DMD). BDNF has cardioprotective qualities that may attenuate dilated cardiomyopa
Autor:
Presley L. Cannon, Manishabrata Bhowmick, Gregg B. Fields, Kristine Y. DeLeon-Pennell, Nicolle L. Patterson, Merry L. Lindsey, Rugmani Padmanabhan Iyer, Elizabeth R. Flynn, Majdouline Asher, Lisandra E. de Castro Brás
Publikováno v:
Journal of Molecular and Cellular Cardiology. 100:109-117
Matrix metalloproteinase-9 (MMP-9) is robustly elevated in the first week post-myocardial infarction (MI). Targeted deletion of the MMP-9 gene attenuates cardiac remodeling post-MI by reducing macrophage infiltration and collagen accumulation through
Autor:
Jeffrey B. Henry, Lisandra E. de Castro Brás, Linda K. Fulton, Merry L. Lindsey, Kristine Y. DeLeon-Pennell, Dustin R. Bratton, Andrew W. Grady, Jared A. White, Yonggang Ma, Mira Jung, Presley L. Cannon, Rugmani Padmanabhan Iyer, Elizabeth R. Flynn
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 311:H822-H836
The purpose of this study was to evaluate the effect of sham surgery in a minimally invasive surgical model of permanent coronary artery occlusion used to generate myocardial infarction (MI) in mice. Adult male C57BL/6J mice (3–6 mo old) were divid
Autor:
Kristine Y. DeLeon-Pennell, Michael A. Puskarich, Lisandra E. de Castro Brás, Presley L. Cannon, Elizabeth R. Flynn, Michael Griswold, Merry L. Lindsey, Yuan Tian, Yufang Jin, Nguyen Nguyen, Alan E. Jones, Ashley DeCoux
Publikováno v:
Critical Care Medicine. 43:2049-2058
Sepsis remains a predominant cause of mortality in the ICU, yet strategies to increase survival have proved largely unsuccessful. This study aimed to identify proteins linked to sepsis outcomes using a glycoproteomic approach to target extracellular
Autor:
Michael R. Garrett, Courtney Cates, De’Aries Shannon, Michael E. Hall, Kristine Y. DeLeon-Pennell, Merry L. Lindsey, Osasere K. Ero, Rugmani Padmanabhan Iyer, Presley L. Cannon, William Buchanan, Mira Jung, Elizabeth R. Flynn, Yonggang Ma
Chronic inflammatory diseases, such as periodontal disease, associate with adverse wound healing in response to myocardial infarction (MI). The goal of this study was to elucidate the molecular basis for impaired cardiac wound healing in the setting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa64d80a872999d039463bc158aa7944
https://europepmc.org/articles/PMC5621894/
https://europepmc.org/articles/PMC5621894/