Proteomic and functional comparison between human induced and embryonic stem cells.

Autor: Brenes AJ; Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Cell Signalling & Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; Human Pluripotent Stem Cell Facility, School of Life Sciences, University of Dundee, Dow St, Dundee DD1 5EH, Dundee, United Kingdom., Griesser E; Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Sinclair LV; Cell Signalling & Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Davidson L; Human Pluripotent Stem Cell Facility, School of Life Sciences, University of Dundee, Dow St, Dundee DD1 5EH, Dundee, United Kingdom., Prescott AR; Dundee Imaging Facility, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Singh F; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Hogg EKJ; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Espejo-Serrano C; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Jiang H; Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Yoshikawa H; Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Platani M; Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Swedlow JR; Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Findlay GM; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Cantrell DA; Cell Signalling & Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Lamond AI; Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.

Publikováno v: ELife [Elife] 2024 Nov 14; Vol. 13. Date of Electronic Publication: 2024 Nov 14.

Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans .

Autor: Lenka DR; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Bhopal, Bhopal, India., Dahe SV; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Bhopal, Bhopal, India., Antico O; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Sahoo P; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Bhopal, Bhopal, India., Prescott AR; Division of Cell Signalling and Immunology, Dundee Imaging Facility, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Muqit MMK; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, United Kingdom., Kumar A; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Bhopal, Bhopal, India.

Publikováno v: ELife [Elife] 2024 Sep 02; Vol. 13. Date of Electronic Publication: 2024 Sep 02.

Golgi-IP, a tool for multimodal analysis of Golgi molecular content.

Autor: Fasimoye R; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815., Dong W; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815.; Department of Chemical Engineering, Stanford University, Stanford, CA 94305.; Department of Genetics, Stanford University, Stanford, CA 94305.; The Institute for Chemistry, Engineering & Medicine for Human Health, Stanford University, Stanford, CA 94305., Nirujogi RS; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815., Rawat ES; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815.; Department of Chemical Engineering, Stanford University, Stanford, CA 94305.; Department of Genetics, Stanford University, Stanford, CA 94305.; The Institute for Chemistry, Engineering & Medicine for Human Health, Stanford University, Stanford, CA 94305., Iguchi M; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815.; Department of Chemical Engineering, Stanford University, Stanford, CA 94305.; Department of Genetics, Stanford University, Stanford, CA 94305.; The Institute for Chemistry, Engineering & Medicine for Human Health, Stanford University, Stanford, CA 94305., Nyame K; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815.; Department of Chemical Engineering, Stanford University, Stanford, CA 94305.; Department of Genetics, Stanford University, Stanford, CA 94305.; The Institute for Chemistry, Engineering & Medicine for Human Health, Stanford University, Stanford, CA 94305.; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305., Phung TK; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815., Bagnoli E; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815., Prescott AR; Dundee Imaging Facility, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Alessi DR; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815., Abu-Remaileh M; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815.; Department of Chemical Engineering, Stanford University, Stanford, CA 94305.; Department of Genetics, Stanford University, Stanford, CA 94305.; The Institute for Chemistry, Engineering & Medicine for Human Health, Stanford University, Stanford, CA 94305.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 May 16; Vol. 120 (20), pp. e2219953120. Date of Electronic Publication: 2023 May 08.

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding.

Autor: Kalogeropulou AF; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee, U.K.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, U.S.A., Purlyte E; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee, U.K., Tonelli F; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee, U.K.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, U.S.A., Lange SM; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee, U.K., Wightman M; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee, U.K., Prescott AR; Dundee Imaging Facility, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Padmanabhan S; The Michael J. Fox Foundation for Parkinson's Research, New York, NY, U.S.A., Sammler E; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee, U.K.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, U.S.A.; Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, U.K., Alessi DR; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee, U.K.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, U.S.A.

Publikováno v: The Biochemical journal [Biochem J] 2022 Sep 16; Vol. 479 (17), pp. 1759-1783.

Condensation properties of stress granules and processing bodies are compromised in myotonic dystrophy type 1.

Autor: Gulyurtlu S; Biomolecular Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK., Magon MS; Biomolecular Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK., Guest P; Biomolecular Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK., Papavasiliou PP; Biomolecular Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK., Morrison KD; Biomolecular Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK., Prescott AR; Division of Cell Signalling and Immunology, School of Life Science, University of Dundee, Dundee DD1 5EH, UK., Sleeman JE; Biomolecular Sciences Research Complex, School of Biology, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2022 Jul 01; Vol. 15 (7). Date of Electronic Publication: 2022 Aug 02.