Výsledky vyhledávání - "Prescillia P. S. Chua"

UV Induces GADD45 in a p53-Dependent and -Independent Manner in Human Keratinocytes

Autor: Duane A. Leedel, Le Luong, Eugene G. Chomey, Tomoko Maeda, Victor A. Tron, Adrian B. Sim, Prescillia P. S. Chua

Publikováno v: Journal of Cutaneous Medicine and Surgery. 7:119-123

Background:GADD45 is a multifunctional protein involved in DNA repair and in cell cycle checkpoint control. p53 plays an important role in regulating DNA repair and in response to UVB in keratinocytes.Objective:GADD45 and p53 expression was examined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555f2b14fb30cad3f8dcba3b9e0cbb15
https://doi.org/10.1177/120347540300700204

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Nucleotide Excision Repair Genes are Upregulated by Low-Dose Artificial Ultraviolet B: Evidence of a Photoprotective SOS Response?

Autor: Adrian B. Sim, Tomoko Maeda, Prescillia P. S. Chua, Victor A. Tron, Osamu Nikaido, Michelle T. Chong

Publikováno v: Journal of Investigative Dermatology. 117:1490-1497

Nucleotide excision repair is a major mechanism of defense against the carcinogenic effects of ultraviolet light. Ultraviolet B causes sunburn and DNA damage in human skin. Nucleotide excision repair has been studied extensively and described in deta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65be536c05974ebc4ffe3a77e6b1a06
https://doi.org/10.1046/j.0022-202x.2001.01562.x

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Examining factors that influence the effectiveness of cleaning antineoplastic drugs from drug preparation surfaces: a pilot study

Autor: Prescillia P S Chua, Quinn Danyluk, Chun-Yip Hon, George Astrakianakis

Publikováno v: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 20(3)

Occupational exposure to antineoplastic drugs has been documented to result in various adverse health effects. Despite the implementation of control measures to minimize exposure, detectable levels of drug residual are still found on hospital work su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c48dd1f023bd7d172d6aa87ac2592e7
https://pubmed.ncbi.nlm.nih.gov/23929731

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Pilot assessment of the antineoplastic drug contamination levels in British Columbian hospitals pre- and post-cleaning

Autor: Quinn Danyluk, Chun-Yip Hon, Winnie C.W. Chu, Prescillia P S Chua, George Astrakianakis

Publikováno v: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 18(1)

Objective. We undertook a pilot study involving six British Columbian hospital pharmacies to determine if antineoplastic drug contamination of surfaces exists and whether residual drugs remain on these surfaces despite being cleaned. Methods. At each

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6874be0c1a824a94676840da4940afe8
https://pubmed.ncbi.nlm.nih.gov/21737485

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Occupational Exposure to Antineoplastic Drugs: Identification of Job Categories Potentially Exposed throughout the Hospital Medication System

Autor: Lynne Nakashima, Chun-Yip Hon, Scott A. Venners, Prescillia P S Chua, Kay Teschke

Publikováno v: Safety and Health at Work
Safety and Health at Work, Vol 2, Iss 3, Pp 273-281 (2011)

Objectives: Studies examining healthcare workers’ exposure to antineoplastic drugs have focused on the drug preparation or drug administration areas. However, such an approach has probably underestimated the overall exposure risk as the drugs need

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::558d183430af9f01fbf46109a854632f
https://pubmed.ncbi.nlm.nih.gov/22953211

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Role of p21Waf-1 in Regulating the G1 and G2/M Checkpoints in Ultraviolet-Irradiated Keratinocytes

Autor: Eugene G. Chomey, Tomoko Maeda, Robin A. Espino, Prescillia P. S. Chua, Victor A. Tron, Michelle T. Chong, Jefferey Q. Cao, Le Luong

Publikováno v: Journal of Investigative Dermatology. (2):513-521

This study examines the role of p21(Waf-1) , a p53-dependent protein, in regulating mechanisms that protect keratinocytes against ultraviolet-B-induced cellular damage. Keratinocytes from p21(Waf-1) or p53-deficient mice were irradiated with ultravio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867fcf74574b5ef9df7453319191e5f8

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GADD45 Regulates G2/M Arrest, DNA Repair, and Cell Death in Keratinocytes Following Ultraviolet Exposure

Autor: Prescillia P. S. Chua, Victor A. Tron, Adrian B. Sim, Atef N. Hanna, Tomoko Maeda, Michelle T. Chong

Publikováno v: Journal of Investigative Dermatology. (1):22-26

GADD45 is a multifunctional protein that is regulated by p53. p53 plays an important role in regulating DNA repair and in the response to ultraviolet light in keratinocytes. This study investigates the role of GADD45 in the response to ultraviolet B.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0d6f78581858d972b1dc5b15afe9f3

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