Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Prerna Vohra"'
Autor:
Ricardo Corona-Torres, Prerna Vohra, Cosmin Chintoan-Uta, Abi Bremner, Vanessa S. Terra, Marta Mauri, Jon Cuccui, Lonneke Vervelde, Brendan W. Wren, Mark P. Stevens
Publikováno v:
Vaccines, Vol 12, Iss 4, p 395 (2024)
Campylobacter is a major cause of acute gastroenteritis in humans, and infections can be followed by inflammatory neuropathies and other sequelae. Handling or consumption of poultry meat is the primary risk factor for human campylobacteriosis, and C.
Externí odkaz:
https://doaj.org/article/425311bf8ef64f3aa1a2c9d2faef25d0
Autor:
Kate Sutton, Tessa Nash, Samantha Sives, Dominika Borowska, Jordan Mitchell, Prerna Vohra, Mark P. Stevens, Lonneke Vervelde
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Salmonella enterica serovar Typhimurium (STm) is a major foodborne pathogen and poultry are a key reservoir of human infections. To understand the host responses to early stages of Salmonella infection in poultry, we infected 2D and 3D enteroids, the
Externí odkaz:
https://doaj.org/article/b691520155b14257884fe3aef74fa49c
Autor:
Marta Mauri, Thippeswamy H. Sannasiddappa, Prerna Vohra, Ricardo Corona-Torres, Alexander A. Smith, Cosmin Chintoan-Uta, Abi Bremner, Vanessa S. Terra, Sherif Abouelhadid, Mark P. Stevens, Andrew J. Grant, Jon Cuccui, Brendan W. Wren, the Glycoengineering of Veterinary Vaccines Consortium
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-26 (2021)
Abstract Background Poultry is the world's most popular animal-based food and global production has tripled in the past 20 years alone. Low-cost vaccines that can be combined to protect poultry against multiple infections are a current global imperat
Externí odkaz:
https://doaj.org/article/47eb9a16750d4941aab1602c1eea67bc
Autor:
Mark Kirkwood, Prerna Vohra, Matt Bawn, Gaëtan Thilliez, Hannah Pye, Jennifer Tanner, Cosmin Chintoan-Uta, Priscilla Branchu, Liljana Petrovska, Timothy Dallman, Neil Hall, Mark P. Stevens, Robert A. Kingsley
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Mark Kirkwood et al. take an epidemiological, genomic, phylogenetic, and experimental approach to assess the evolutionary origins and virulence of the U288 and ST34 isolates of Salmonella enterica in affecting livestock and potentially humans. Their
Externí odkaz:
https://doaj.org/article/8c52b28de3c14eabb4f9ecfc56e2eac4
Publikováno v:
Veterinary Research, Vol 50, Iss 1, Pp 1-11 (2019)
Abstract Salmonella enterica is a veterinary and zoonotic pathogen of global importance. While murine and cell-based models of infection have provided considerable knowledge about the molecular basis of virulence of Salmonella, relatively little is k
Externí odkaz:
https://doaj.org/article/ce907d11ab6d496b92557541137011d2
Autor:
Prerna Vohra, Roy R. Chaudhuri, Matthew Mayho, Christina Vrettou, Cosmin Chintoan-Uta, Nicholas R. Thomson, Jayne C. Hope, John Hopkins, Mark P. Stevens
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Salmonella enterica subspecies enterica is an animal and zoonotic pathogen of global importance. Cattle are a significant reservoir of human non-typhoidal salmonellosis and can suffer enteric and systemic disease owing to the abil
Externí odkaz:
https://doaj.org/article/02f510ff6f364fa7bb56ddb2ab716d4c
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101147- (2020)
Summary: Aging has a profound effect on the immune system, termed immunosenescence, resulting in increased incidence and severity of infections and decreased efficacy of vaccinations. We previously showed that immunosurveillance in the intestine, ach
Externí odkaz:
https://doaj.org/article/38973d1f03734c7393c2d3d5705f4e38
Autor:
Adam Balic, Cosmin Chintoan-Uta, Prerna Vohra, Kate M. Sutton, Robin L. Cassady-Cain, Tuan Hu, David S. Donaldson, Mark P. Stevens, Neil A. Mabbott, David A. Hume, Helen M. Sang, Lonneke Vervelde
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The follicle-associated epithelium (FAE) is a specialized structure that samples luminal antigens and transports them into mucosa-associated lymphoid tissues (MALT). In mammals, transcytosis of antigens across the gut epithelium is performed by a sub
Externí odkaz:
https://doaj.org/article/1e6f95e7566549e7a484aadf1329aa6f
Autor:
Sherif Abouelhadid, Simon J. North, Paul Hitchen, Prerna Vohra, Cosmin Chintoan-Uta, Mark Stevens, Anne Dell, Jon Cuccui, Brendan W. Wren
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT In eukaryotes, glycosylation plays a role in proteome stability, protein quality control, and modulating protein function; however, similar studies in bacteria are lacking. Here, we investigate the roles of general protein glycosylation syst
Externí odkaz:
https://doaj.org/article/0d0372c0457a437f9746456acb366609
Autor:
Prerna Vohra, Cosmin Chintoan-Uta, Vanessa S. Terra, Abi Bremner, Jon Cuccui, Brendan W. Wren, Lonneke Vervelde, Mark P. Stevens
Publikováno v:
Vaccines, Vol 8, Iss 3, p 520 (2020)
Campylobacter jejuni is the leading bacterial cause of human gastroenteritis worldwide and the handling or consumption of contaminated poultry meat is the key source of infection. C. jejuni proteins FlpA and SodB and glycoconjugates containing the C.
Externí odkaz:
https://doaj.org/article/e481098a2b0540fda771257f042eeb51