Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Prerna Kotak"'
Autor:
Manuel Muñoz, Vishal Kothari, Tim Machajewski, Fernando Rock, Scott M Turner, Selorm Tamakloe, Colin Magowan, Gail Lee, Darren Finkelstein, Tim Hom, Dennis Monteleone, Subramanian Karu, Erine Budi, Prerna Kotak, Shamra Martin, Katherine Jenkins, Martin Decaris
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/70486df34a3a4e7aabe10f1ca719d9a7
Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
Autor:
Martin L. Decaris, Johanna R. Schaub, Chun Chen, Jacob Cha, Gail G. Lee, Megi Rexhepaj, Steve S. Ho, Vikram Rao, Megan M. Marlow, Prerna Kotak, Erine H. Budi, Lisa Hooi, Jianfeng Wu, Marina Fridlib, Shamra P. Martin, Shaoyi Huang, Ming Chen, Manuel Muñoz, Timothy F. Hom, Paul J. Wolters, Tushar J. Desai, Fernando Rock, Katerina Leftheris, David J. Morgans, Eve-Irene Lepist, Patrick Andre, Eric A. Lefebvre, Scott M. Turner
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Rationale αv integrins, key regulators of transforming growth factor-β activation and fibrogenesis in in vivo models of pulmonary fibrosis, are expressed on abnormal epithelial cells (αvβ6) and fibroblasts (αvβ1) in fibrotic lungs. Obj
Externí odkaz:
https://doaj.org/article/f75a5266ef724db48db905d69406f78e
Autor:
Vishal Kothari, Colin Magowan, Darren Finkelstein, Gail Lee, Chun Chen, Tim Hom, Manuel Muñoz, Dennis Monteleone, Subramanian Karur, Marta Bogaczynska, Erin Budi, Prerna Kotak, Shamra Martin, Katherine Jenkins, Simon Wong, Timothy Machajewski, Fernando Rock, Scott Turner
Publikováno v:
Regular and Young Investigator Award Abstracts.
Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF
Autor:
Patrick Andre, Martin Decaris, Chun Chen, Munoz Manuel, Hom Timothy, Scott M. Turner, Ming Chen, Tushar J. Desai, Megan M. Marlow, Cha Jacob, Eric Lefebvre, Steve S. Ho, Paul J. Wolters, Shaoyi Huang, Eve-Irene Lepist, Katerina Leftheris, David J Morgans, Lisa Hooi, Johanna R. Schaub, Vikram R. Rao, Jianfeng Wu, Marina Fridlib, Fernando Rock, Megi Rexhepaj, Erine H. Budi, Prerna Kotak, Gail Lee, Shamra Martin
Publikováno v:
Respiratory research, vol 22, iss 1
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)
Rationale αv integrins, key regulators of transforming growth factor-β activation and fibrogenesis in in vivo models of pulmonary fibrosis, are expressed on abnormal epithelial cells (αvβ6) and fibroblasts (αvβ1) in fibrotic lungs. Objectives W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8943da51a8a3553a1e3711bc9a9ed07
https://escholarship.org/uc/item/5q12m0vq
https://escholarship.org/uc/item/5q12m0vq
Autor:
Angela L. Linderholm, Justin M. Oldham, Genevieve Montas, Claude Jourdan Le Saux, Nancy K. Hills, Scott M. Turner, Kirk D. Jones, Paul J. Wolters, Prerna Kotak, Jeffrey A. Golden, B. Trinh, Darren Leong, Ying Wei, Martin Decaris, Harold A. Chapman, Jin-Woo Song, Elena Foster
Publikováno v:
N Engl J Med
EGCG and Pulmonary Fibrosis Nine patients who were scheduled to undergo lung biopsy for pulmonary fibrosis were given epigallocatechin gallate (EGCG) for 2 weeks. Levels of fibrotic markers in lung...
Autor:
Eric Lefebvre, Maureen Reilly, Chun Chen, Katerina Leftheris, Vikram R. Rao, Lisa Hooi, Jianfeng Wu, Eduard Gorina, Scott Turner, Gail Lee, Jake Cha, Tony Chen, Johanna R. Schaub, Martin Decaris, Prerna Kotak, Munoz Manuel, Patrick Andre, Hom Timothy, Shamra Martin, Megi Rexhepaj, Cooper Nicole
Publikováno v:
Idiopathic interstitial pneumonias.
Integrin αVβ6 (epithelial cell) and αVβ1 (fibroblast)-mediated activation of TGF-β have been shown to promote fibrosis in the bleomycin lung injury model, and elevated levels of αVβ6 have been found in human IPF lung tissue. Through the develo