Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Prerna Bhargava"'
Autor:
Jyotsna Shah, Song Liu, Hari-Hara Potula, Prerna Bhargava, Iris Cruz, Denise Force, Ammar Bazerbashi, Ranjan Ramasamy
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Rapid and simple serological assays for characterizing antibody responses are important in the current COVID-19 pandemic caused by SARS-CoV-2. Multiplex immunoblot (IB) assays termed COVID-19 IB assays were developed for detecting
Externí odkaz:
https://doaj.org/article/15d9e685f82b46b2b8eb3cdd608e1004
Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types
Autor:
Benjamin E. Mead, Jose Ordovas-Montanes, Alexandra P. Braun, Lauren E. Levy, Prerna Bhargava, Matthew J. Szucs, Dustin A. Ammendolia, Melanie A. MacMullan, Xiaolei Yin, Travis K. Hughes, Marc H. Wadsworth, Rushdy Ahmad, Seth Rakoff-Nahoum, Steven A. Carr, Robert Langer, James J. Collins, Alex K. Shalek, Jeffrey M. Karp
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-24 (2018)
Abstract Background Single-cell genomic methods now provide unprecedented resolution for characterizing the component cell types and states of tissues such as the epithelial subsets of the gastrointestinal tract. Nevertheless, functional studies of t
Externí odkaz:
https://doaj.org/article/af6abd99fa9b45318eb28d7964c53335
Autor:
Lingling Dai, Prerna Bhargava, Kristopher J. Stanya, Ryan K. Alexander, Yae-Huei Liou, David Jacobi, Nelson H. Knudsen, Alexander Hyde, Matthew R. Gangl, Sihao Liu, Chih-Hao Lee
Publikováno v:
Molecular Metabolism, Vol 6, Iss 10, Pp 1186-1197 (2017)
Objective: Alternative activation (M2) of adipose tissue resident macrophage (ATM) inhibits obesity-induced metabolic inflammation. The underlying mechanisms remain unclear. Recent studies have shown that dysregulated lipid homeostasis caused by incr
Externí odkaz:
https://doaj.org/article/591691068e984936bef452226fe6690b
Autor:
Ammar Bazerbashi, Denise Force, Hari Hara Potula, Ranjan Ramasamy, Iris Du Cruz, Jyotsna S Shah, Prerna Bhargava, Song Liu
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Infectious Diseases
BMC Infectious Diseases
Background Rapid and simple serological assays for characterizing antibody responses are important in the current COVID-19 pandemic caused by SARS-CoV-2. Multiplex immunoblot (IB) assays termed COVID-19 IB assays were developed for detecting IgG and
Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types
Autor:
Matthew J. Szucs, Marc H. Wadsworth, Alexandra Provost Braun, Rushdy Ahmad, Seth Rakoff-Nahoum, Travis K. Hughes, Alex K. Shalek, Robert Langer, Jeffrey M. Karp, Steven A. Carr, Xiaolei Yin, Lauren Levy, Jose Ordovas-Montanes, Melanie A. MacMullan, Benjamin E. Mead, Dustin A. Ammendolia, James J. Collins, Prerna Bhargava
Publikováno v:
BioMed Central
BMC Biology, Vol 16, Iss 1, Pp 1-24 (2018)
BMC Biology, Vol 16, Iss 1, Pp 1-24 (2018)
Background Single-cell genomic methods now provide unprecedented resolution for characterizing the component cell types and states of tissues such as the epithelial subsets of the gastrointestinal tract. Nevertheless, functional studies of these subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9170b76d35ce12fdc6fc4d489e37a56
https://orcid.org/0000-0002-7203-4299
https://orcid.org/0000-0002-7203-4299
Autor:
Matthew R. Gangl, Ryan K. Alexander, Prerna Bhargava, Yae-Huei Liou, Lingling Dai, Chih-Hao Lee, Sihao Liu, Nelson H. Knudsen, Alexander L. Hyde, Kristopher J. Stanya, David Jacobi
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 10, Pp 1186-1197 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1186-1197 (2017)
Objective Alternative activation (M2) of adipose tissue resident macrophage (ATM) inhibits obesity-induced metabolic inflammation. The underlying mechanisms remain unclear. Recent studies have shown that dysregulated lipid homeostasis caused by incre
Autor:
Prerna Bhargava, Ning Mao, Jason H. Yang, Bernhard O. Palsson, James J. Collins, Douglas McCloskey
Publikováno v:
Cell host & microbe, vol 22, iss 6
PMC
Yang, J H, Bhargava, P, McCloskey, D, Mao, N, Palsson, B & Collins, J J 2017, ' Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function ', Cell Host & Microbe, vol. 22, pp. 757-765 . https://doi.org/10.1016/j.chom.2017.10.020
PMC
Yang, J H, Bhargava, P, McCloskey, D, Mao, N, Palsson, B & Collins, J J 2017, ' Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function ', Cell Host & Microbe, vol. 22, pp. 757-765 . https://doi.org/10.1016/j.chom.2017.10.020
Bactericidal antibiotics alter microbial metabolism as part of their lethality and can damage mitochondria in mammalian cells. In addition, antibiotic susceptibility is sensitive to extracellular metabolites, but it remains unknown whether metabolite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0faa64d3f4cb957f129a8f15f5cac65f
https://escholarship.org/uc/item/0b87q57m
https://escholarship.org/uc/item/0b87q57m
Autor:
Lingling Dai, Prerna Bhargava, Stanya, Kristopher, Alexander, Ryan, Yae-Huei Liou, Jacobi, David, Knudsen, Nelson, Hyde, Alexander, Gangl, Matthew, Sihao Liu, Chih-Hao Lee
the study described the role for alternatively activated macrophages regulated by the IL-4/PPAR axis in the protection against lipotoxicity-induced cell dysfunction and metabolic inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19a7340c92188166e7290a0537ac14a8
Autor:
Saloni R. Jain, Michael A. Lobritz, Arnaud Gutierrez, Meagan Hamblin, James J. Collins, Prerna Bhargava
Publikováno v:
Elsevier
Physiologic and environmental factors can modulate antibiotic activity and thus pose a significant challenge to antibiotic treatment. The quinolone class of antibiotics, which targets bacterial topoisomerases, fails to kill bacteria that have grown t
Autor:
Mead, Benjamin, Ordovas-Montanes, Jose, Braun, Alexandra, Levy, Lauren, Prerna Bhargava, Szucs, Matthew, Ammendolia, Dustin, MacMullan, Melanie, Xiaolei Yin, Hughes, Travis, Wadsworth, Marc, Rushdy Ahmad, Rakoff-Nahoum, Seth, Carr, Steven, Langer, Robert, Collins, James, Shalek, Alex, Karp, Jeffrey
Figure S1. Image analysis of cell clusters and flow cytometry. A Bright-field microscopy after 6 days of ENR + CD culture shows annular morphology and darkened lumen of cell clusters consistent with presence of granule-rich cells. B Percentage of tot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404baa657584568837a5223ac3f8e7ff