Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Prenyltransferase activity"'
Autor:
Tiangang Liu, Takahiro Mori, Stephen A. Shinsky, Haibing He, Xin Mu, Guangkai Bian, David W. Christianson, Zixin Deng, Ikuro Abe, Minjian Huang, Corey J Herbst-Gervasoni, Anwei Hou, Shu Cheng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Catalytic versatility is an inherent property of many enzymes. In nature, terpene cyclases comprise the foundation of molecular biodiversity as they generate diverse hydrocarbon scaffolds found in thousands of terpenoid natural products. Here, we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e33f9e982924a65b44d1c0dad6d12f
https://doaj.org/article/c70d380b1bf6424697e7827e67324201
https://doaj.org/article/c70d380b1bf6424697e7827e67324201
Publikováno v:
Biochemical and Biophysical Research Communications. 520(2):291-296
Cis-prenyltransferases are enzymes responsible for the biosynthesis of glycosyl carrier lipids, natural rubber, and some secondary metabolites. Certain organisms, including some archaeal species, possess multiple genes encoding cis-prenyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29dc44cdc7fb3820469afb7ad4c08b9
https://nagoya.repo.nii.ac.jp/records/30061
https://nagoya.repo.nii.ac.jp/records/30061
Autor:
Fu Kuroiwa, Yukino Miyagi-Inoue, Satoshi Yamashita, Yukie Takani, Yuzuru Tozawa, Miki Suenaga-Hiromori, Akira Nishino, Haruhiko Yamaguchi, Kakeru Suzuki, Yasuko Mandal, Seiji Takahashi
Prenyltransferases mediate the biosynthesis of various types of polyisoprene compound in living organisms. Natural rubber (NR) of the Para rubber tree (Hevea brasiliensis) is synthesized as a result of prenyltransferase activity, with the proteins HR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c5f28e6798e0bd1d073caddfd787d4e
https://doi.org/10.1101/2021.04.29.441905
https://doi.org/10.1101/2021.04.29.441905
Publikováno v:
J Struct Biol
The unusual diterpene (C20) synthase copalyl diphosphate synthase from Penicillium verruculosum (PvCPS) is the first bifunctional terpene synthase identified with both prenyltransferase and class II cyclase activities in a single polypeptide chain wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1284dfee62dc5b1ead731f255548fb68
https://europepmc.org/articles/PMC7067624/
https://europepmc.org/articles/PMC7067624/
Publikováno v:
Journal of Biological Chemistry. 292:17351-17361
cis-Prenyltransferases (cis-PTs) constitute a large family of enzymes conserved during evolution and present in all domains of life. In eukaryotes and archaea, cis-PT is the first enzyme committed to the synthesis of dolichyl phosphate, an obligate l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6772314380f486fb08e0f4228a29ee2f
https://doi.org/10.1074/jbc.m117.806034
https://doi.org/10.1074/jbc.m117.806034
Autor:
Fabricio Medina-Bolivar, Victor S. Sobolev, Agnes M Rimando, Lingling Fang, Tianhong Yang, Keithanne Mockaitis
Publikováno v:
Plant Physiology. 171:2483-2498
Prenylated stilbenoids synthesized in some legumes exhibit plant pathogen defense properties and pharmacological activities with potential benefits to human health. Despite their importance, the biosynthetic pathways of these compounds remain to be e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da43bdd2b55f672c6e8aa5bd25e2347a
https://doi.org/10.1104/pp.16.00610
https://doi.org/10.1104/pp.16.00610
Publikováno v:
Biochemistry. 57(29)
Protein prenylation involves the attachment of a hydrophobic isoprenoid moiety to the C-terminus of proteins. Several small GTPases, including members of the Ras and Rho subfamilies, require prenylation for their normal and pathological functions. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa9e9480b5a52c9832ddff110efb5eb
https://pubmed.ncbi.nlm.nih.gov/29940100
https://pubmed.ncbi.nlm.nih.gov/29940100
Autor:
S. B. Malkowicz, John E. Tomaszewski, Nathaniel J. Fredericks, Priti Lal, Hankun Yin, William J. Fredericks, S. Bruce Malkowicz, Raghunath Puthiyaveettil, Frank J. Rauscher
Publikováno v:
International Journal of Oncology. 43:638-652
Current studies of the TERE1 (UBIAD1) protein emphasize its multifactorial influence on the cell, in part due to its broad sub-cellular distribution to mitochondria, endoplasmic reticulum and golgi. However, the profound effects of TERE1 relate to it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553a5281c7c3707b441fe6628841b188
https://doi.org/10.3892/ijo.2013.1985
https://doi.org/10.3892/ijo.2013.1985
Autor:
Keith A. Cengel, W. Gillies McKenna, Stephen M. Hahn, Eric J. Bernhard, Junmin Wu, Douglas L. Fraker, Thomas Brunner
Activating K-ras mutations are found in ∼90% of pancreatic carcinomas and may contribute to the poor prognosis of these tumors. Because radiotherapy is frequently used in pancreatic cancer treatment, we assessed the contribution of oncogenic K-ras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d004374cc4092ff07d1b9995bf44623b
https://ora.ox.ac.uk/objects/uuid:96bf45b8-43a0-45f0-b7b7-def5ec8615dd
https://ora.ox.ac.uk/objects/uuid:96bf45b8-43a0-45f0-b7b7-def5ec8615dd
Autor:
Hitoshi Hori, Tsuyoshi Inoue, Ryosuke Munakata, Yusuke Tsurumaru, Akifumi Sugiyama, Jun-ichi Azuma, Yoshihiro Uto, Kazufumi Yazaki, Takao Koeduka, Kanako Sasaki
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 76(7):1389-1393
Coumarins, a large group of polyphenols, play important roles in the defense mechanisms of plants, and they also exhibit various biological activities beneficial to human health, often enhanced by prenylation. Despite the high abundance of prenylated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2e4156075dd08398f3782cc95a2fd4
http://hdl.handle.net/2433/176985
http://hdl.handle.net/2433/176985