Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Premkumar B. Saganti"'
Autor:
Polina Malatesta, Konstantinos Kyriakidis, Megumi Hada, Hiroko Ikeda, Akihisa Takahashi, Premkumar B. Saganti, Alexandros G. Georgakilas, Ioannis Michalopoulos
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 88 (2024)
During future space missions, astronauts will be exposed to cosmic radiation and microgravity (μG), which are known to be health risk factors. To examine the differentially expressed genes (DEG) and their prevalent biological processes and pathways
Externí odkaz:
https://doaj.org/article/205d2daabd7142fb96a56c2bbc8624c1
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Future space missions by national space agencies and private industry, including space tourism, will include a diverse makeup of crewmembers with extensive variability in age, sex, and race or ethnic groups. The relative risk (RR) model is u
Externí odkaz:
https://doaj.org/article/4d9778f456d64bb09f2a84d3ee1e0857
Autor:
Sakuya Yamanouchi, Jordan Rhone, Jian-Hua Mao, Keigi Fujiwara, Premkumar B. Saganti, Akihisa Takahashi, Megumi Hada
Publikováno v:
Life, Vol 10, Iss 9, p 187 (2020)
During space travel, humans are continuously exposed to two major environmental stresses, microgravity (μG) and space radiation. One of the fundamental questions is whether the two stressors are interactive. For over half a century, many studies wer
Externí odkaz:
https://doaj.org/article/6c6b3d584b864c879e984d6581586e95
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Radiation Therapy (RT) has been critical in cancer treatment regimens to date. However, it has been shown that ionizing radiation is also associated with increased risk of damage to healthy tissues. At high radiation doses, varied effects including i
Externí odkaz:
https://doaj.org/article/31c1f6ad7ce54f53a5d70b0f587519e1
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4327 (2019)
Previously, we investigated the dose response for chromosomal aberration (CA) for exposures corresponding to less than one particle traversal per cell nucleus by high energy and charge (HZE) particles, and showed that the dose responses for simple ex
Externí odkaz:
https://doaj.org/article/88403e1a09b84ad6b2d9db1e363d5c17
Autor:
Megumi Hada, Hiroko Ikeda, Jordan R. Rhone, Andrew J. Beitman, Ianik Plante, Hikaru Souda, Yukari Yoshida, Kathryn D. Held, Keigi Fujiwara, Premkumar B. Saganti, Akihisa Takahashi
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 43 (2018)
Space radiation and microgravity (μG) are two major environmental stressors for humans in space travel. One of the fundamental questions in space biology research is whether the combined effects of μG and exposure to cosmic radiation are interactiv
Externí odkaz:
https://doaj.org/article/5e4599c9110c41af8f74696389fad61f
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 502:136-141
Light ion breakup cross sections are important for studies of cosmic ray interactions in the inter-stellar medium or radiation protection considerations of energy deposition in shielding and tissues. Abrasion cross sections for heavy ion reactions ha
Autor:
Jordan Rhone, Yukari Yoshida, Keigi Fujiwara, Premkumar B. Saganti, Takuya Adachi, Jian-Hua Mao, Sakuya Yamanouchi, Akihisa Takahashi, Megumi Hada
Publikováno v:
Biological Sciences in Space. 35:15-23
Publikováno v:
Acta Astronautica. 166:529-536
In addition to traditional interest by various governments in space exploration, there is growing interest in private missions to Mars and other deep space destinations within the next decade. Private missions could consider persons not restricted by
Publikováno v:
Clinical Oncology and Cancer Biology. :1-8
It is well-known that Radiation-induced fibrosis (RIF) is a late event occurring months to years after the initial radiation exposure. Fibrotic lesions have been shown to manifest in many tissues including the skin, heart, lung, liver and kidney. Fib