Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Premila Rathnam"'
Autor:
Young A Han, Premila Rathnam, Brij B. Saxena, Mukul Singh, Jeffrey Laurence, Sidney Lerner, Dingyi Fu
Publikováno v:
AIDS. 23:917-922
Objective: An effective vaginal microbicide against sexual HIV transmission remains elusive, with requirements for adherence to appropriate application of effective, nontoxic products being a major deterrent. We explored methods to enable sustained r
Autor:
Eileen Kisilis, Ozgur Oktem, Brij B. Saxena, Lei Zhu, Premila Rathnam, Meirong Hao, Arkadiy Bomshteyn, Meena Katdare
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:6349-6358
Betulonic acid, derived from betulinol, a pentacyclic styrene, has shown a highly specific anti-prostate cancer activity in in vitro cell cultures. However, due to the lack of solubility of betulonic acid in aqueous medium, its potent anti-cancer act
Autor:
Mukul Singh, Premila Rathnam, Brij B. Saxena, Y Bukharovich, A Saxena, A Clavio, T Reimers, Scott Perkins
Publikováno v:
Reproduction in Domestic Animals. 37:9-17
Adult female dogs were immunized with 0.5 mg bovine luteinizing hormone receptor (LH-R) encapsulated in a silastic subdermal implant and subsequently with four intramuscular booster injections of 0.1 mg LH-R each. Circulating LH-R antibody was detect
Publikováno v:
Journal of reproductive immunology. 63(2)
Human lutropin (hLH) and human chorionic gonadotropin (hCG) are structurally and functionally similar and play important roles in reproduction via a common gonadal receptor (LH-R). However, hormone specific hCG-beta subunit contains 24 additional ami
Autor:
Premila Rathnam, Brij B. Saxena, Abbie Clavio, Mukul Singh, Thomas J. Reimers, Anjali Saxena, Scott Perkins, E. Yaroslaw Bukharovich
Publikováno v:
American journal of veterinary research. 64(3)
Objective—To determine the effect of immunization with bovine luteinizing hormone receptor (LH-R) on ovarian function of cats. Animals—9 adult female domestic cats. Procedure—7 cats were immunized with 0.5 mg of LH-R encapsulated in a silastic
Publikováno v:
European journal of endocrinology. 132(2)
Rathnam P, Lin S, Saxena BB. Identification of luteinizing hormone receptor binding inhibitor in bovine corpora lutea. Eur J Endocrinol 1995;132:213–17. ISSN 0804–4643 A 7000 g supernatant, obtained during the purification of luteinizing hormone
Publikováno v:
Journal of reproductive immunology. 22(1)
Monoclonal antibodies (Mabs) were produced against bovine Lutropin receptor (LH-R). Antibodies were detected by an enzyme linked immunosorbant assay (ELISA). Hybridomas were subcloned to achieve monoclonality. Ascites were developed in Balb/c mice. H
Autor:
E. B. Saxena, Premila Rathnam
Publikováno v:
Journal of immunoassay. 11(2)
We describe here, a novel and effective use of a specific receptor for Luteinizing Hormone (LH) coupled to controlled pore-glass beads (CPG) and LH antibodies to glass beads (GB), in selective removal of residual LH from purified Follicle Stimulating
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 719:1-10
Glycopeptides located at asparagine residues at position 52 in the α-subunit and at position 7 in the β-subunit of human follicle-stimulating hormone (FSH) were obtained by pronase digestion of the intact human FSH molecule. The glycopeptide fracti
Autor:
Robert Landesman, G. N. Gupta, Premila Rathnam, B. Dattatreyamurty, Mukul Singh, Brij B. Saxena
Publikováno v:
Journal of Obstetrics and Gynaecology. 4:S16-S22
SummaryA Continuing search for new methods of fertility regulation has faced both promises and problems. More effective methods have led to more side effects, whereas methods with lesser problems have been less effective. Newer approaches are logical