Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Premature ageing"'
Autor:
Cristina Capanni, Elisa Schena, Maria Letizia Di Giampietro, Alessandra Montecucco, Elisabetta Mattioli, Giovanna Lattanzi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Lamin A is a main constituent of the nuclear lamina and contributes to nuclear shaping, mechano-signaling transduction and gene regulation, thus affecting major cellular processes such as cell cycle progression and entry into senescence, cellular dif
Externí odkaz:
https://doaj.org/article/8b102589514c425a97142ec1dfa8d03b
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 579 (2023)
Telomeres are dynamic DNA nucleoprotein structures located at the end of chromosomes where they maintain genomic stability. Due to the end replication problem, telomeres shorten with each cell division. Critically short telomeres trigger cellular sen
Externí odkaz:
https://doaj.org/article/4693233396d644a9a43660ac3bcd37d9
Publikováno v:
Przegląd Dermatologiczny, Vol 107, Iss 2, Pp 179-183 (2020)
Hutchinson-Gilford progeria syndrome is an extremely rare genetic disorder characterized by premature ageing involving the skin, bones, heart, and blood vessels. The incidence is 1 in several million births. It occurs sporadically and is probably an
Externí odkaz:
https://doaj.org/article/981657b82b6546849b82dfb67aba466e
Publikováno v:
Immunity & Ageing, Vol 17, Iss 1, Pp 1-10 (2020)
Abstract Background End-stage renal disease is associated with premature ageing of the T cell immune system but inter-individual variation is substantial. The hypothesis was tested that advanced immunological T cell ageing assessed by peripheral T ce
Externí odkaz:
https://doaj.org/article/7f61df2ef1354b6caecacb090065bcb1
Autor:
Whittaker, D. Hugh, author, Sturgeon, Timothy J., author, Okita, Toshie, author, Zhu, Tianbiao, author
Publikováno v:
Compressed Development : Time and Timing in Economic and Social Development, 2020, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780198744948.003.0002
Publikováno v:
Nasza Dermatologia Online, Vol 9, Iss 2, Pp 148-151 (2018)
Werner’s Syndrome also known as Pangeria is an autosomal recessive disorder characterized by premature aging, increased risk of malignancies and atherosclerosis. The Global incidence rate is less than 1 in 100,000 live births. The incidence is high
Externí odkaz:
https://doaj.org/article/8fe6992e2cf04498835aa5f9d207e376
В работе на основе комплексного исследования рассмотрены вопросы адаптации людей предпенсионного возраста в условиях сочетанного вли
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62533d3deec05fe49fcae9394e61fe3b
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Jun 01. 112(22), E2910-E2919.
Externí odkaz:
https://www.jstor.org/stable/26463517
Autor:
Thomas Ebert, Sven-Christian Pawelzik, Anna Witasp, Samsul Arefin, Sam Hobson, Karolina Kublickiene, Paul G. Shiels, Magnus Bäck, Peter Stenvinkel
Publikováno v:
Toxins, Vol 12, Iss 4, p 227 (2020)
Persistent low-grade inflammation and premature ageing are hallmarks of the uremic phenotype and contribute to impaired health status, reduced quality of life, and premature mortality in chronic kidney disease (CKD). Because there is a huge global bu
Externí odkaz:
https://doaj.org/article/6906bc1801be44999323ec0474306d45
Publikováno v:
Molecular Aspects of Medicine. 86
Post-translational modifications (PTMs) have been proposed as a link between the oxidative stress-inflammation ageing trinity, thereby affecting several hallmarks of ageing.Phosphorylation, acetylation, and ubiquitination cover >90% of all the report