Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Prema S. Rao"'
Autor:
U Subrahmanyeswara Rao, Prema S Rao
Publikováno v:
Tumor Biology, Vol 39 (2017)
One long-term complication of chronic intestinal inflammation is the development of colorectal cancer. However, the mechanisms linking inflammation to the colorectal tumorigenesis are poorly defined. Previously, we have demonstrated that galectin-4 i
Externí odkaz:
https://doaj.org/article/ee5c759904904aabb2db66cc6408a7a6
Autor:
Prema S. Rao, U. Subrahmanyeswara Rao
Publikováno v:
Molecular and Cellular Biochemistry. 476:743-755
Statins are potent inhibitors of the mevalonate/cholesterol biosynthetic pathway and are widely prescribed for the prevention of cardiovascular diseases. Here, we carried out a comprehensive analysis of the effects of three statins, simvastatin, ator
Publikováno v:
Cancer Research. 80:1855-1855
The widely used statin drugs for the prevention of cardiovascular diseases are envisioned to have the potential to control cancer. Repurposing these cardiovascular drugs for cancer prevention and/or treatment is an attractive proposition as these dru
Publikováno v:
The pharmacogenomics journal. 18(4)
Comparison of human genome sequences from different individuals has unraveled that genes involved in the drug efficacy and metabolism are polymorphic, harboring mutations, splicing variations and other alterations. These data provide a reasonable exp
Autor:
Prema S. Rao, U. Subrahmanyeswara Rao
Publikováno v:
Tumor Biology, Vol 39 (2017)
One long-term complication of chronic intestinal inflammation is the development of colorectal cancer. However, the mechanisms linking inflammation to the colorectal tumorigenesis are poorly defined. Previously, we have demonstrated that galectin-4 i
Autor:
Prema S. Rao, Kalkunte S. Srivenugopal, Arun Satelli, Sanjay K. Srivastava, Sheng Zhang, U. Subrahmanyeswara Rao
Publikováno v:
PROTEOMICS. 9:2776-2787
RNF2, a member of polycomb group (PcG) proteins, is involved in chromatin remodeling. However, mechanisms that regulate RNF2 function are unknown. To identify such mechanisms, RNF2 was expressed in HEK-293 cells and analyzed by 2-D electrophoresis. R
Publikováno v:
Clinical Cancer Research. 11:5833-5839
Purpose: Cancers exposed to chemotherapy develop multidrug resistance, a major cause for chemotherapy failure. One mechanism of multidrug resistance development is due to overexpression of P-glycoprotein (Pgp) in these cancer cells. Thus, a prechemot
Autor:
Meena Jaggi, Prema S. Rao, David J. Smith, Margaret J. Wheelock, Keith R. Johnson, George P. Hemstreet, K.C. Balaji
Publikováno v:
Cancer Research. 65:483-492
The cadherin family of transmembrane glycoproteins plays a critical role in cell-to-cell adhesion and cadherin dysregulation is strongly associated with cancer metastasis and progression. In this study, we report a novel interaction between protein k
Publikováno v:
Biochemical and Biophysical Research Communications. 307:254-260
Progression to androgen independence (AI) is the main cause of death in prostate cancer. Our prior differential gene expression studies by microarray analysis in progressive prostate cancer cell line model identified dysregulation of protein kinase C
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 35(7)
Assessment of the human epidermal growth factor receptor-2 (Her2/ErbB2) and estrogen receptor (ER) and progesterone receptor (PR) expression in breast cancer has been an accepted standard to predict clinical outcome. Expression of these receptors in