Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Prema M. Nair"'
Autor:
Gang Liu, Tatt Jhong Haw, Malcolm R. Starkey, Ashleigh M. Philp, Stelios Pavlidis, Christina Nalkurthi, Prema M. Nair, Henry M. Gomez, Irwan Hanish, Alan CY. Hsu, Elinor Hortle, Sophie Pickles, Joselyn Rojas-Quintero, Raul San Jose Estepar, Jacqueline E. Marshall, Richard Y. Kim, Adam M. Collison, Joerg Mattes, Sobia Idrees, Alen Faiz, Nicole G. Hansbro, Ryutaro Fukui, Yusuke Murakami, Hong Sheng Cheng, Nguan Soon Tan, Sanjay H. Chotirmall, Jay C. Horvat, Paul S. Foster, Brian GG. Oliver, Francesca Polverino, Antonio Ieni, Francesco Monaco, Gaetano Caramori, Sukhwinder S. Sohal, Ken R. Bracke, Peter A. Wark, Ian M. Adcock, Kensuke Miyake, Don D. Sin, Philip M. Hansbro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract Toll-like receptor 7 (TLR7) is known for eliciting immunity against single-stranded RNA viruses, and is increased in both human and cigarette smoke (CS)-induced, experimental chronic obstructive pulmonary disease (COPD). Here we show that th
Externí odkaz:
https://doaj.org/article/c49c73a4f4614f95ae1cab28b0686048
Autor:
Grace L. Burns, Jessica K. Bruce, Kyra Minahan, Andrea Mathe, Thomas Fairlie, Raquel Cameron, Crystal Naudin, Prema M. Nair, Michael D. E. Potter, Mudar Zand Irani, Steven Bollipo, Robert Foster, Lay T. Gan, Ayesha Shah, Natasha A. Koloski, Paul S. Foster, Jay C. Horvat, Martin Veysey, Gerald Holtmann, Nick Powell, Marjorie M. Walker, Nicholas J. Talley, Simon Keely
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundFunctional dyspepsia is characterised by chronic symptoms of post-prandial distress or epigastric pain not associated with defined structural pathology. Increased peripheral gut-homing T cells have been previously identified in patients. To
Externí odkaz:
https://doaj.org/article/27a57fd705f9440da66c1548f1069a5f
Autor:
Prema M Nair, Malcolm R Starkey, Tatt Jhong Haw, Gang Liu, Adam M Collison, Joerg Mattes, Peter A. Wark, Jonathan C Morris, Nikki M Verrills, Andrew R Clark, Alaina J Ammit, Philip M Hansbro
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 10, Pp n/a-n/a (2019)
Abstract Objective Chronic obstructive pulmonary disease (COPD) is a progressive disease that causes significant mortality and morbidity worldwide and is primarily caused by the inhalation of cigarette smoke (CS). Lack of effective treatments for COP
Externí odkaz:
https://doaj.org/article/3f9da2127a404b8dbf99a5f36fff84a6
Autor:
Kening Fan, Guy D Eslick, Prema M Nair, Grace L Burns, Marjorie M Walker, Emily C Hoedt, Simon Keely, Nicholas J Talley
Publikováno v:
Journal of Gastroenterology and Hepatology. 37:1222-1234
Human colonic spirochetosis (CS) is usually due toBrachyspira pilosicolior Brachyspira aalborgiinfection. While traditionally considered to be commensal bacteria, there are scattered case reports and case series of gastrointestinal (GI) symptoms in C
Autor:
Jay C. Horvat, Eugene Nalivaiko, José Maria Barbosa-Filho, Ama Tawiah Essilfie, Claudio Roberto Bezerra-Santos, Marcia Regina Piuvezam, Evgeny Bondarenko, Phil Hansbro, Prema M. Nair
Publikováno v:
Revista Brasileira de Farmacognosia. 30:224-232
Cissampelos sympodialis Eichler, Menispermaceae, is a native Brazilian plant used in folk medicine to treat asthma and has central nervous system effects. Anxiety is a prevalent comorbidity of asthma raising the potential for the development of monot
Autor:
Paul S. Foster, Andrea Mathe, Nicholas J. Talley, Gerald Holtmann, Crystal Naudin, Grace Burns, Prema M. Nair, Martin Veysey, Robert Foster, Lay T. Gan, Kyra Minahan, Natasha A. Koloski, Jessica Bruce, Michael D. Potter, Raquel Cameron, Marjorie M. Walker, Mudar Zand Irani, Nick Powell, Jay C. Horvat, Thomas Fairle, Ayesha Shah, Steven Bollipo, Simon Keely
Background and aimsFunctional dyspepsia is characterised by chronic symptoms of post- prandial distress or epigastric pain not associated with defined structural pathology. Increased peripheral gut-homing T cell have been previously identified in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a547b42cad4dfa928146fd648faf1765
https://doi.org/10.1101/2021.11.22.21266508
https://doi.org/10.1101/2021.11.22.21266508
Autor:
Bernadette Jones, Peter A. B. Wark, Michael Fricker, Fien M. Verhamme, Caitlin M Gillis, Philip M. Hansbro, Guy Brusselle, B Christina Nalkurthi, Hannelore Van Eeckhoutte, James M. Murphy, Jay C. Horvat, Peter Vandenabeele, Prema M. Nair, Ken R. Bracke, Zhe Lu, Gang Liu, Tamariche Buyle-Huybrecht, Tom Vanden Berghe
Publikováno v:
American journal of respiratory and critical care medicine
Rationale: Necroptosis, mediated by RIPK3 (receptor-interacting protein kinase 3) and MLKL (mixed lineage kinase domain-like), is a form of regulated necrosis that can drive tissue inflammation and destruction; however, its contribution to chronic ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbfc16e39d711bcb9b614857476c44a
https://hdl.handle.net/10453/155657
https://hdl.handle.net/10453/155657
Autor:
Jessica K. Bruce, Grace L. Burns, Wai Sinn Soh, Prema M. Nair, Simonne Sherwin, KeNing Fan, Laura R. Dowling, Bridie J. Goggins, Natasha Koloski, Michael Potter, Steven Bollipo, Robert Foster, Lay T. Gan, Martin Veysey, Dana J. Philpott, Stephen E. Girardin, Gerald Holtmann, Gerard E. Kaiko, Marjorie M. Walker, Nicholas J. Talley, Simon Keely
Publikováno v:
Brain, behavior, and immunity. 101
Functional dyspepsia (FD) affects up to 15% of the population and is characterised by recurring upper gastrointestinal (GI) symptoms occurring in the absence of clinically identifiable pathology. Psychological stress is a key factor associated with t
Autor:
Simon Keely, Karen L. Edelblum, Alastair J.M. Watson, Grace Burns, Thomas J. Kelly, Edward M. Bonder, Inga Sandrock, Jonathan Agos, Immo Prinz, Prema M. Nair, David J. Granville, Matthew R. Zeglinski, Mudar Zand Irani, Madeleine D. Hu, Natasha B. Golovchenko, Wai Sinn Soh, Alexander Lemenze
Publikováno v:
Gastroenterology
Background & Aims: Excessive shedding of apoptotic enterocytes into the intestinal lumen is observed in inflammatory bowel disease and is correlated with disease relapse. Based on their cytolytic capacity and surveillance behavior, we investigated wh
Autor:
Philip M. Hansbro, Paul S. Foster, Jay C. Horvat, Stelios Pavlidis, Don D. Sin, H. Gomez, Ian M. Adcock, Peter A. B. Wark, Gang Liu, Yusuke Murakami, Irwan Hanish, Richard Kim, Alan Hsu, Tatt Jhong Haw, Malcolm R. Starkey, Sheena Tam, Prema M. Nair, Brian G. Oliver, Ryutaro Fukui, Kensuke Miyake
Toll-like receptor (TLR)7 is known for eliciting immunity against single-stranded RNA viruses. TLR7 was increased in both human and cigarette smoke (CS)-induced experimental chronic obstructive pulmonary disease (COPD). Severity of CS-induced emphyse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485787273637f53a018f73684f4ad53c
https://hdl.handle.net/10453/155664
https://hdl.handle.net/10453/155664