Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Prem P. Chapagain"'
Autor:
Kristen A. Johnson, Melissa R. Budicini, Nisha Bhattarai, Tej Sharma, Sarah Urata, Bernard S. Gerstman, Prem P. Chapagain, Sheng Li, Robert V. Stahelin
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 3, Pp 100512- (2024)
Ebola virus (EBOV) causes severe hemorrhagic fever in humans and is lethal in a large percentage of those infected. The EBOV matrix protein viral protein 40 kDa (VP40) is a peripheral binding protein that forms a shell beneath the lipid bilayer in vi
Externí odkaz:
https://doaj.org/article/8a3341cab06f4c60a01e5ef7dbe9ff15
Publikováno v:
ACS Omega, Vol 3, Iss 12, Pp 18639-18645 (2018)
Externí odkaz:
https://doaj.org/article/48be3dc2be9f42eeb66bdd0237f20db9
Autor:
Kristen A. Johnson, Nisha Bhattarai, Melissa R. Budicini, Carolyn M. LaBonia, Sarah Catherine B. Baker, Bernard S. Gerstman, Prem P. Chapagain, Robert V. Stahelin
Publikováno v:
Viruses, Vol 13, Iss 7, p 1375 (2021)
Ebolavirus (EBOV) is a negative-sense RNA virus that causes severe hemorrhagic fever in humans. The matrix protein VP40 facilitates viral budding by binding to lipids in the host cell plasma membrane and driving the formation of filamentous, pleomorp
Externí odkaz:
https://doaj.org/article/aa3d0b2cb2cf43b2a24ac1e035e12cb8
Autor:
Kristen A. Johnson, Rudramani Pokhrel, Melissa R. Budicini, Bernard S. Gerstman, Prem P. Chapagain, Robert V. Stahelin
Publikováno v:
Pathogens, Vol 9, Iss 5, p 402 (2020)
The Ebola virus (EBOV) harbors seven genes, one of which is the matrix protein eVP40, a peripheral protein that is sufficient to induce the formation of virus-like particles from the host cell plasma membrane. eVP40 can form different structures to f
Externí odkaz:
https://doaj.org/article/d0f80969c1a64582985191904cdabae9
Autor:
Kaveesha J. Wijesinghe, Luke McVeigh, Monica L. Husby, Nisha Bhattarai, Jia Ma, Bernard S. Gerstman, Prem P. Chapagain, Robert V. Stahelin
Publikováno v:
Viruses, Vol 12, Iss 4, p 482 (2020)
Marburg virus (MARV) is a lipid-enveloped negative sense single stranded RNA virus, which can cause a deadly hemorrhagic fever. MARV encodes seven proteins, including VP40 (mVP40), a matrix protein that interacts with the cytoplasmic leaflet of the h
Externí odkaz:
https://doaj.org/article/2cbf1afdc68c4152b39a754ce1321ef4
Publikováno v:
The Journal of Physical Chemistry B. 127:52-61
We recently developed the red fluorescent protein (RFP) mCherry-XL, which is threefold brighter than its predecessor, mCherry, with a directed evolution approach using fluorescence-lifetime flow cytometry selections. The enhanced brightness is due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f978d90b0a727a441d22eb6ac4b8f4
https://doi.org/10.1021/acs.jpcb.2c05584
https://doi.org/10.1021/acs.jpcb.2c05584
Publikováno v:
Journal of Chemical Information and Modeling. 63:2095-2103
Methyl CpG binding proteins (MBPs) are transcription factors that recognize the methylated CpG sites in DNA and mediate the DNA methylation signal into various downstream cellular processes. The C2H2 zinc finger (ZF) protein, Kaiso, also an MBP, pref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab270913912754f78c72b49e123aa1cb
https://doi.org/10.1021/acs.jcim.2c01294
https://doi.org/10.1021/acs.jcim.2c01294
Autor:
Kevin Jeanne Dit Fouque, Sarah N. Sipe, Alyssa Garabedian, German Mejia, Linjia Su, Md Lokman Hossen, Prem P. Chapagain, Fenfei Leng, Jennifer S. Brodbelt, Francisco Fernandez-Lima
Publikováno v:
J Am Soc Mass Spectrom
The mammalian high mobility group protein AT-hook 2 (HMGA2) is an intrinsically disordered DNA-binding protein expressed during embryogenesis. In the present work, the conformational and binding dynamics of HMGA2 and HMGA2 in complex with a 22-nt (DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3389070603403b63c2d1910778e53dab
https://doi.org/10.1021/jasms.2c00101
https://doi.org/10.1021/jasms.2c00101
Autor:
Popular Pandey, Nisha Bhattarai, Linjia Su, Xuewen Wang, Fenfei Leng, Bernard Gerstman, Prem P. Chapagain, Jin He
Publikováno v:
ACS Sensors. 7:555-563
Label-free detection and analysis of proteins in their natural form and their dynamic interactions with substrates at the single-molecule level are important for both fundamental studies and various applications. Herein, we demonstrate a simple poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b625c7de10613b60e09b1d0464d49a4d
https://doi.org/10.1021/acssensors.1c02385
https://doi.org/10.1021/acssensors.1c02385
Autor:
Rudramani Pokhrel, Nisha Bhattarai, Prabin Baral, Bernard S. Gerstman, Jae H. Park, Martin Handfield, Prem P. Chapagain
Publikováno v:
Journal of Chemical Theory and Computation. 18:516-525
There has been an alarming rise in antibacterial resistant infections in recent years due to the widespread use of antibiotics, and there is a dire need for the development of new antibiotics utilizing novel modes of action. Lantibiotics are promisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3220b333a8e424a72eb0a00380f2df4
https://doi.org/10.1021/acs.jctc.1c00666
https://doi.org/10.1021/acs.jctc.1c00666