Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Prem N, Yadav"'
Autor:
Parishmita Sarma, Carlo Marion C. Carino, Deeksha Seetharama, Shubhi Pandey, Hemlata Dwivedi-Agnihotri, Xue Rui, Yubo Cao, Kouki Kawakami, Poonam Kumari, Yu-Chih Chen, Kathryn E. Luker, Prem N. Yadav, Gary D. Luker, Stéphane A. Laporte, Xin Chen, Asuka Inoue, Arun K. Shukla
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Chemokine receptors constitute an important subfamily of G protein-coupled receptors (GPCRs), and they are critically involved in a broad range of immune response mechanisms. Ligand promiscuity among these receptors makes them an interesting
Externí odkaz:
https://doaj.org/article/00c1bfe069ce44fd80ee66e1ab0d2340
Autor:
Smita Pal, Poonam Mehta, Ankita Pandey, Anam Ara, Ujjala Ghoshal, Uday C. Ghoshal, Rajesh Pandey, Raj Kamal Tripathi, Prem N. Yadav, Ramachandran Ravishankar, Tapas K. Kundu, Singh Rajender
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The emergence and rapid evolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused a global crisis that required a detailed characterization of the dynamics of mutational pattern of the viral genome for comprehending its epidemi
Externí odkaz:
https://doaj.org/article/7da72e959f0d4f85b14420778724f17f
Publikováno v:
Neurobiology of Disease, Vol 118, Iss , Pp 94-107 (2018)
GPR40 (Free fatty acid receptor 1) has emerged as an important therapeutic target for diabetes. Several studies have demonstrated the association of comorbid psychiatric conditions with decreased n-3 polyunsaturated fatty acids, which may act as an a
Externí odkaz:
https://doaj.org/article/9a2ebfb655ce44b1ab8a26dcad9eb9fb
Publikováno v:
Progress in molecular biology and translational science. 193(1)
Pain sensation is a normal physiological response to alert and prevent further tissue damage. It involves the perception of external stimuli by somatosensory neurons, then transmission of the message to various other types of neurons present in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::902558d2721e0ef7bccf0e8fdc2446ff
https://pubmed.ncbi.nlm.nih.gov/36357081
https://pubmed.ncbi.nlm.nih.gov/36357081
Autor:
Jetta, Sandeep Kumar, Rapaka, Naimisha, B, Thirupataiah, Gangireddy, Sujeevan Reddy, Navneet, Bung, Arijit, Roy, Gopalakrishnan, Bulusu, Ankita, Mishra, Prem N, Yadav, Parimal, Misra, Manojit, Pal
Publikováno v:
Bioorganic chemistry. 129
Efforts have been devoted for the discovery and development of positive allosteric modulators (PAMs) of 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2ce6cce7ee40df7e58e45459b795009
https://pubmed.ncbi.nlm.nih.gov/36272252
https://pubmed.ncbi.nlm.nih.gov/36272252
Autor:
Parishmita Sarma, Hye-Jin Yoon, Carlo Marion C. Carino, Deeksha S, Ramanuj Banerjee, Yaejin Yun, Jeongsek Ji, Kyungjin Min, Shubhi Pandey, Hemlata Dwivedi-Agnihotri, Xue Rui, Yubo Cao, Kouki Kawakami, Poonam Kumari, Yu-Chih Chen, Kathryn E. Luker, Manish K. Yadav, Ashutosh Ranjan, Madhu Chaturvedi, Jagannath Maharana, Mithu Baidya, Prem N. Yadav, Gary D. Luker, Stéphane A. Laporte, Xin Chen, Asuka Inoue, Hyung Ho Lee, Arun K. Shukla
Chemokine receptors constitute an important subfamily of G protein-coupled receptors (GPCRs), and they are critically involved in a broad range of immune response mechanisms. Ligand promiscuity among these receptors makes them an interesting target t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b46111109a2a0f8be1f755063459da6
https://doi.org/10.1101/2022.06.06.494935
https://doi.org/10.1101/2022.06.06.494935
Autor:
Muhammad Wahajuddin, Sandeep Kumar Singh, Shalini Dogra, Chandan Sona, Deepmala Umrao, Ajeet Kumar, Prem N. Yadav, Mamunur Rashid
Publikováno v:
Psychoneuroendocrinology. 101:128-137
The last two decades of research has established histamine (HA) as a neurotransmitter. Since H3R antagonists are known to modulate several neurotransmitters besides HA, H3R antagonists have shown potential for the treatment of different central nervo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18358c7502a2ce7525acd6581656edf
https://doi.org/10.1016/j.psyneuen.2018.11.007
https://doi.org/10.1016/j.psyneuen.2018.11.007
Autor:
Mohammad Imran Siddiqi, Ajeet Kumar, Rama Pati Tripathi, Maninder Singh, Kartikey Singh, Chandan Sona, Prem N. Yadav, Ankita Mishra, Vikash Ojha
Publikováno v:
European Journal of Medicinal Chemistry. 164:499-516
Allosteric modulators of G-protein-coupled receptors have lately gained significant traction in drug discovery. Recent studies have shown that allosteric modulation of serotonin 2C receptor (5-HT2C) as a viable strategy for the treatment of various c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b811c3ba549767d58419295711b31ca9
https://doi.org/10.1016/j.ejmech.2018.12.070
https://doi.org/10.1016/j.ejmech.2018.12.070
Autor:
Prem N. Yadav, Shalini Dogra, Indrapal Singh Aidhen, Arun kumar Boda, Ishani Bose, Kasireddy Sudarshan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:585-590
Isocoumarins are lactone ring-containing natural products, are quite abundant in microbes and higher plants, and have been shown to exhibit a broad range of pharmacological properties. However, the molecular mechanism or target of this class of molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8327948a2faebcb2108baea180313b9
https://doi.org/10.1016/j.bmcl.2018.12.057
https://doi.org/10.1016/j.bmcl.2018.12.057
Autor:
Sakesh Kumar, Poonam Kumari, Mohammad Imran Siddiqi, Lalan Kumar, Prem N. Yadav, Veena D. Yadav, Sanjay Batra, Maninder Singh
Publikováno v:
ChemMedChem. 16(12)
The synthesis of 5-formyl-6-aryl-6H-indolo[3,2,1-de][1,5] naphthyridine-2-carboxylates by reaction between 1-formyl-9H-β-carbolines and cinnamaldehydes in the presence of pyrrolidine in water with microwave irradiation is described. Pharmacophoric m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57e6bab2a1a830e3b6edcee490c70d0
https://pubmed.ncbi.nlm.nih.gov/33599108
https://pubmed.ncbi.nlm.nih.gov/33599108