Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Prem K, Premsrirut"'
Autor:
Rachelle P. Mendoza, Amir Momeni, Nayanendu Saha, Juwairiya Arshi, Elmer C. Gabutan, Nichole Alejandro, Alejandro Zuretti, Prem K. Premsrirut, Dimitar B. Nikolov
Publikováno v:
Microorganisms, Vol 11, Iss 12, p 2940 (2023)
The viral agent SARS-CoV-2 clearly affects several organ systems, including the cardiovascular system. Angiopoietins are involved in vascular integrity and angiogenesis. Angiopoietin-1 (Ang1) promotes vessel stabilization, while angiopoietin-2 (Ang2)
Externí odkaz:
https://doaj.org/article/c805ffd9a79c4f5e939fd06e43625d10
Autor:
Zhiru Li, Jacqueline L Bruce, Barry Cohen, Caileigh V Cunningham, William E Jack, Katell Kunin, Bradley W Langhorst, Jacob Miller, Reynes A Moncion, Catherine B Poole, Prem K Premsrirut, Guoping Ren, Richard J Roberts, Nathan A Tanner, Yinhua Zhang, Clotilde K S Carlow
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268692 (2022)
Effective management of the COVID-19 pandemic requires widespread and frequent testing of the population for SARS-CoV-2 infection. Saliva has emerged as an attractive alternative to nasopharyngeal samples for surveillance testing as it does not requi
Externí odkaz:
https://doaj.org/article/92026c356e18426da597bb818ba0347a
Autor:
Rachelle P. Mendoza, Chongfeng Bi, Hui-Ting Cheng, Elmer Gabutan, Guillerre Jan Pagaspas, Nadia Khan, Helen Hoxie, Stephen Hanna, Kelly Holmes, Nicholas Gao, Raychel Lewis, Huaien Wang, Daniel Neumann, Angela Chan, Meril Takizawa, James Lowe, Xiao Chen, Brianna Kelly, Aneeza Asif, Keena Barnes, Nusrat Khan, Brandon May, Tasnim Chowdhury, Gabriella Pollonini, Nourelhoda Gouda, Chante Guy, Candice Gordon, Nana Ayoluwa, Elvin Colon, Noah Miller-Medzon, Shanique Jones, Rauful Hossain, Arabia Dodson, Meimei Weng, Miranda McGaskey, Ana Vasileva, Andrew E. Lincoln, Robby Sikka, Anne L. Wyllie, Ethan M. Berke, Jenny Libien, Matthew Pincus, Prem K. Premsrirut
Publikováno v:
EClinicalMedicine, Vol 38, Iss , Pp 101028- (2021)
Background: The negative impact of continued school closures during the height of the COVID-19 pandemic warrants the establishment of cost-effective strategies for surveillance and screening to safely reopen and monitor for potential in-school transm
Externí odkaz:
https://doaj.org/article/8ebb8f16ec5144ed93bb7b50cd01ff28
Autor:
Chen-Ju Lin, Zeina Nasr, Prem K. Premsrirut, John A. Porco, Jr., Yoshitaka Hippo, Scott W. Lowe, Jerry Pelletier
Publikováno v:
Cell Reports, Vol 1, Iss 4, Pp 325-333 (2012)
The energetically demanding process of translation is linked to multiple signaling events through mTOR-mediated regulation of eukaryotic initiation factor (eIF)4F complex assembly. Disrupting mTOR constraints on eIF4F activity can be oncogenic and al
Externí odkaz:
https://doaj.org/article/781d116f459f47b881583994d1a2e332
Autor:
William S. Morris, Prem K. Premsrirut, Xianda Zhao, Ce Yuan, Dechen Wangmo, Subbaya Subramanian
Colorectal cancer (CRC) is one of the most common malignancies in both morbidity and mortality. Immune checkpoint blockade (ICB) treatments have been successful in a portion of mismatch repair-deficient (dMMR) CRC patients but failed in the mismatch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a24250ce5ca03e15c539659fe96d7c31
https://doi.org/10.1101/2021.08.23.457444
https://doi.org/10.1101/2021.08.23.457444
Publikováno v:
Cancer Research. 82:946-946
Serrated colorectal cancer (CRC) is an aggressive and treatment-resistant form of colorectal carcinogenesis that accounts for one-fourth of the patients with CRC1. At the molecular level, serrated CRC is characterized by epigenetic modifications term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33130cd99b0f2f3d9a40eb702ff1cd52
https://doi.org/10.1158/1538-7445.am2022-946
https://doi.org/10.1158/1538-7445.am2022-946
Autor:
Chongfeng Bi, Rachelle Mendoza, Hui-Ting Cheng, Elmer Gabutan, Guillerre Jan Pagaspas, Nadia Khan, Helen Hoxie, Kelly Holmes, Nicholas Gao, Raychel Lewis, Huaien Wang, Daniel Neumann, Angela Chan, Meril Takizawa, James Lowe, Brianna Kelly, Aneeza Asif, Keena Barnes, Nusrat Khan, Brandon May, Mecca Wright, Tasnim Chowdhury, Gabriella Pollonini, Nourelhoda Gouda, Chante Guy, Candice Gordon, Nana Ayoluwa, Elvin Colon, Noah Miller-Medzon, Shanique Jones, Rauful Hossain, Morgan McCarten, Arabia Dodson, Meimei Wang, Miranda McGaskey, Ana Vasileva, Sean Seibel, James Connolly, Michele Esposito, Jane Kim, Andrew E. Lincoln, Robby Sikka, Anne L. Wyllie, Ethan M. Berke, Jenny Libien, Matthew Pincus, Stephen Chang, Prem K. Premsrirut
Publikováno v:
SSRN Electronic Journal.
Background: The negative impact of continued school closures during the height of the COVID-19 pandemic warrants the establishment of cost-effective strategies for surveillance and screening to safely reopen and monitor for potential in-school transm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f67f55101549a9871f7484784401c2a9
https://doi.org/10.2139/ssrn.3793566
https://doi.org/10.2139/ssrn.3793566
Autor:
Anne L, Wyllie, Prem K, Premsrirut
Publikováno v:
JAMA. 327:182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e1f6fc79ea97f74b5a5bfb83cc6da8
https://doi.org/10.1001/jama.2021.21703
https://doi.org/10.1001/jama.2021.21703
Autor:
Raphael Pelossof, Christof Fellmann, Qing Xiang, Darjus F. Tschaharganeh, Thomas Hoffmann, Vishal Thapar, Christina S. Leslie, Johannes Zuber, Ralph Garippa, Scott W. Lowe, Yuanzhe Guan, Chun-Hao Huang, Gunnar Rätsch, Nishi Sinha, Prem K. Premsrirut, Christian Widmer, Lauren Fairchild, Dan-Yu Lai, Vipin T. Sreedharan
Publikováno v:
Nature biotechnology
We present SplashRNA, a sequential classifier to predict potent microRNA-based short hairpin RNAs (shRNAs). Trained on published and novel data sets, SplashRNA outperforms previous algorithms and reliably predicts the most efficient shRNAs for a give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882a7982313d98863f3c1a8eae92ab82
https://doi.org/10.1038/nbt.3807
https://doi.org/10.1038/nbt.3807
Autor:
Johannes Zuber, Allison Maurice, Scott W. Lowe, Yu-ting Yang, Lukas Dow, Ana Vasileva, Chia-Lin Wang, Prem K. Premsrirut
Publikováno v:
Cancer Research. 80:6119-6119
The cost of drug development has skyrocketed to an estimated $2.6B for every FDA approved drug primarily due to failures from lack of efficacy or safety. This suggests that our current preclinical validation process has been insufficient in predictin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::481ea0078df01662beaecd5dd278e71d
https://doi.org/10.1158/1538-7445.am2020-6119
https://doi.org/10.1158/1538-7445.am2020-6119