Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Prem Chapagain"'
Autor:
Menglang Yuan, Iqbal Mahmud, Keisuke Katsushima, Kandarp Joshi, Olivier Saulnier, Rudramani Pokhrel, Bongyong Lee, Wathsala Liyanage, Haritha Kunhiraman, Stacie Stapleton, Ignacio Gonzalez-Gomez, Rangaramanujam M. Kannan, Tanja Eisemann, Elayaraja Kolanthai, Sudipta Seal, Timothy J. Garrett, Saed Abbasi, Kimberly Bockley, Justin Hanes, Prem Chapagain, George Jallo, Robert J. Wechsler-Reya, Michael D. Taylor, Charles G. Eberhart, Animesh Ray, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract The prognosis of childhood medulloblastoma (MB) is often poor, and it usually requires aggressive therapy that adversely affects quality of life. microRNA-211 (miR-211) was previously identified as an important regulator of cells that descen
Externí odkaz:
https://doaj.org/article/d02fc40d411f4baba42e490fbec01155
Autor:
Jan Sklenicka, Tung Tran, Maria S. Ramirez, Haley M. Donow, Angel J. Magaña, Travis LaVoi, Yasir Mamun, Verónica Jimenez, Prem Chapagain, Radleigh Santos, Clemencia Pinilla, Marc A. Giulianotti, Marcelo E. Tolmasky
Publikováno v:
Antibiotics, Vol 13, Iss 7, p 672 (2024)
Resistance to amikacin and other major aminoglycosides is commonly due to enzymatic acetylation by the aminoglycoside 6′-N-acetyltransferase type I enzyme, of which type Ib [AAC(6′)-Ib] is the most widespread among Gram-negative pathogens. Findin
Externí odkaz:
https://doaj.org/article/c197c7880abf460db84e42d2d2218354
Autor:
Keisuke Katsushima, Rudramani Pokhrel, Iqbal Mahmud, Menglang Yuan, Rabi Murad, Prabin Baral, Rui Zhou, Prem Chapagain, Timothy Garrett, Stacie Stapleton, George Jallo, Chetan Bettegowda, Eric Raabe, Robert J. Wechsler-Reya, Charles G. Eberhart, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Medulloblastoma (MB) develops through various genetic, epigenetic, and non-coding (nc) RNA-related mechanisms, but the roles played by ncRNAs, particularly circular RNAs (circRNAs), remain poorly defined. CircRNAs are increasingly recognized
Externí odkaz:
https://doaj.org/article/189686aa08f2466da897e79be7e129e1
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12586 (2023)
The emergence and the high transmissibility of the XBB.1.5 and XBB.1.16 subvariants of the SARS-CoV-2 omicron has reignited concerns over the potential impact on vaccine efficacy for these and future variants. We investigated the roles of the XBB.1.5
Externí odkaz:
https://doaj.org/article/4fc476321d604222abb55cd257dc556b
Autor:
Dinesh Devadoss, Arpan Acharya, Marko Manevski, Dominika Houserova, Michael D. Cioffi, Kabita Pandey, Madhavan Nair, Prem Chapagain, Mehdi Mirsaeidi, Glen M. Borchert, Siddappa N. Byrareddy, Hitendra S. Chand
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104685- (2022)
Summary: Noncoding RNAs are important regulators of mucoinflammatory response, but little is known about the contribution of airway long noncoding RNAs (lncRNAs) in COVID-19. RNA-seq analysis showed a more than 4-fold increased expression of IL-6, IC
Externí odkaz:
https://doaj.org/article/438d7fbe77eb4d9c97afa855b8f33d41
Autor:
Janelle Nunez-Castilla, Vitalii Stebliankin, Prabin Baral, Christian A. Balbin, Masrur Sobhan, Trevor Cickovski, Ananda Mohan Mondal, Giri Narasimhan, Prem Chapagain, Kalai Mathee, Jessica Siltberg-Liberles
Publikováno v:
Viruses, Vol 14, Iss 7, p 1415 (2022)
Molecular mimicry between viral antigens and host proteins can produce cross-reacting antibodies leading to autoimmunity. The coronavirus SARS-CoV-2 causes COVID-19, a disease curiously resulting in varied symptoms and outcomes, ranging from asymptom
Externí odkaz:
https://doaj.org/article/cdf4e613172a4c598f5b3969e586bf49
Autor:
Kenneth Rocha, Jesus Magallon, Craig Reeves, Kimberly Phan, Peter Vu, Crista L. Oakley-Havens, Stella Kwan, Maria Soledad Ramirez, Travis LaVoi, Haley Donow, Prem Chapagain, Radleigh Santos, Clemencia Pinilla, Marc A. Giulianotti, Marcelo E. Tolmasky
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1218 (2021)
The aminoglycoside 6′-N-acetyltransferase type Ib (AAC(6′)-Ib) is a common cause of resistance to amikacin and other aminoglycosides in Gram-negatives. Utilization of mixture-based combinatorial libraries and application of the positional scannin
Externí odkaz:
https://doaj.org/article/1a871c56781944109a6547b83c05aebb
Autor:
Rudramani Pokhrel, Pornthep Sompornpisut, Prem Chapagain, Brian Olson, Bernard Gerstman, R. B. Pandey
Publikováno v:
AIP Advances, Vol 8, Iss 12, Pp 125129-125129-8 (2018)
The VP40 protein plays a critical role in coordinating the virion assembly, budding, and replication of the Ebola virus. Efforts have been made in recent years to understand various aspects of VP40 structure, dynamics, and function such as assembly o
Externí odkaz:
https://doaj.org/article/6fd57b7fff6f448f9259e5573ee67043
Autor:
Rahul Mittal, Desiree Nguyen, Luca H. Debs, Amit P. Patel, George Liu, Vasanti M. Jhaveri, Sae-In S. Kay, Jeenu Mittal, Emmalee S. Bandstra, Ramzi T. Younis, Prem Chapagain, Dushyantha T. Jayaweera, Xue Zhong Liu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Zika virus (ZIKV) is an emerging healthcare threat. The presence of the mosquito Aedes species across South and Central America in combination with complementary climates have incited an epidemic of locally transmitted cases of ZIKV infection in Braz
Externí odkaz:
https://doaj.org/article/a6bf945752ce466e97ad42d7ec2f10a2
Autor:
Pawlos S Tsegay, Daniela Hernandez, Fei Qu, Mustapha Olatunji, Yasir Mamun, Prem Chapagain, Yuan Liu
Publikováno v:
Nucleic Acids Research. 51:166-181
DNA repair is mediated by DNA synthesis guided by a DNA template. Recent studies have shown that DNA repair can also be accomplished by RNA-guided DNA synthesis. However, it remains unknown how RNA can guide DNA synthesis to repair DNA damage. In thi