Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Prem B. Chanda"'
Publikováno v:
The Journal of Organic Chemistry. 86:6184-6194
In contrast to methyl phenylacetates, methyl arylacetates do not provide syn-aldols in the dicyclohexylboron triflate/triethylamine (Chx2BOTf/Et3N)-mediated enolboration–aldolization reaction. Howe...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c6d86f404a0c7cd3795b8d272528964
https://doi.org/10.1021/acs.joc.0c03024
https://doi.org/10.1021/acs.joc.0c03024
Autor:
Bishnu P. Regmi, Niranjan Parajuli, Ashma Adhikari, Prem B. Chanda, Niru Thapa, Anup Adhikari, Bibek Raj Bhattarai, Puja Kc, Ashika Aryal, Sushila Maharjan
Publikováno v:
RSC Advances. 11:38126-38145
Unnatural amino acids have gained significant attention in protein engineering and drug discovery as they allow the evolution of proteins with enhanced stability and activity. The incorporation of unnatural amino acids into proteins offers a rational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8976a49b2faff533094792007e4180
https://doi.org/10.1039/d1ra07028b
https://doi.org/10.1039/d1ra07028b
Autor:
Prem B. Chanda, Gregory D. Vite, Naidu S. Chowdari, Christopher Gartshore, Dale L. Boger, Anindya Sarkar, Shinji Tadano, Qian Zhang, Jelena Momirov, Sanjeev Gangwar
Publikováno v:
Organic Letters. 22:8714-8719
A short, scalable total synthesis of meayamycin is described by an approach that entails a longest linear sequence of 12 steps (22 steps overall) from commercially available chiral pool materials (ethyl l-lactate, BocNH-Thr-OH, and d-ribose) and intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17c615bc98bb2e36e870a5d2769f6bf1
https://doi.org/10.1021/acs.orglett.0c03308
https://doi.org/10.1021/acs.orglett.0c03308
Autor:
Angela Y, Thomas, Tommy L, Walls Iii, Brionna N, Nelson, Stafford W, Primeaux, Prem B, Chanda
Publikováno v:
The Journal of organic chemistry. 86(9)
In contrast to methyl phenylacetates, methyl arylacetates do not provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::172dc36268717478d04f325a25bb7002
https://pubmed.ncbi.nlm.nih.gov/33835804
https://pubmed.ncbi.nlm.nih.gov/33835804
Publikováno v:
Tetrahedron Letters. 56:3019-3022
Unlike the hydrocarbon analogs, this first report of enolboration–aldolization of 3,3,3-trifluoropropanoic acid provides essentially pure anti-diastereomers of α-trifluoromethyl-β-hydroxy carboxylic acids in 77–90% yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2d6e8ca23e4109c98a0d1e3aa950776
https://doi.org/10.1016/j.tetlet.2014.12.045
https://doi.org/10.1016/j.tetlet.2014.12.045
Publikováno v:
Bioorganicmedicinal chemistry. 24(20)
The design, synthesis, and evaluation of methyl 1,2,8,8a-tetrahydrocyclopropa[c]imidazolo[4,5-e]indol-4-one-6-carboxylate (CImI) derivatives are detailed representing analogs of duocarmycin SA and yatakemycin containing an imidazole replacement for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab8b7046a1bf14edaf16e6d4d790948
https://pubmed.ncbi.nlm.nih.gov/27221071
https://pubmed.ncbi.nlm.nih.gov/27221071
Publikováno v:
Organic Letters. 14:4346-4349
Unlike the enolboration-aldolization of methyl propanoate, the choice of either the solvent or temperature determines the diastereoselectivity during the enolboration-aldolization of methyl phenylacetate. In CH(2)Cl(2), the reaction favors the anti-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bebec52e6283fb4992c4ab80ac5334e
https://doi.org/10.1021/ol301782s
https://doi.org/10.1021/ol301782s
Publikováno v:
Tetrahedron Letters. 55:1289-1291
A systematic examination of enolboration–aldolization of propanoic acid has led to an efficient synthesis of anti -β-hydroxy-α-methyl carboxylic acids in consistently high yields and diastereoselectivities by using B -bromodicyclohexylborane as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b25cc14e76833633dec4dc62dacd84b5
https://doi.org/10.1016/j.tetlet.2013.12.048
https://doi.org/10.1016/j.tetlet.2013.12.048
Publikováno v:
ChemInform. 46
The reaction is based on the anti-stereoselective enolboration-aldolisation of 3,3,3-trifluoropropanoic acid with aryl or alkylaldehydes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b880c66705e5b99256bc1b0d907ab15
https://doi.org/10.1002/chin.201540093
https://doi.org/10.1002/chin.201540093
Publikováno v:
Tetrahedron Letters. 54:5886-5888
The enolization temperature overrides all other aspects, including the sterics of the alkyl group of the boron reagent and the alkoxy group of the ester during the enolboration–aldolization of phenylacetates. This study has led to the first n -Bu 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8074bbc284e4f821e14d1a4d429bd4c9
https://doi.org/10.1016/j.tetlet.2013.08.106
https://doi.org/10.1016/j.tetlet.2013.08.106