Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Prem, Kumarathasan"'
Autor:
Devi Ganesh, Prem Kumarathasan, Errol M Thomson, Carly St-Germain, Erica Blais, James Crapo, Renaud Vincent
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151810 (2016)
Endothelin-1 is a potent vasoconstrictor and mitogenic peptide involved in the regulation of vasomotor tone and maintenance of blood pressure. Oxidative stress activates the endothelin system, and is implicated in pulmonary and cardiovascular disease
Externí odkaz:
https://doaj.org/article/f6d74fca89784c41b0d42da844a283ea
Autor:
Prem Kumarathasan, Renaud Vincent, Erica Blais, Anu Saravanamuthu, Pallavi Gupta, Heather Wyatt, Ronald Mitchel, Mohammed Hannan, Akilesh Trivedi, Stewart Whitman
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65486 (2013)
BACKGROUND: There is evidence for a role of ionizing radiation in cardiovascular diseases. The goal of this work was to identify changes in oxidative and nitrative stress pathways and the status of the endothelinergic system during progression of ath
Externí odkaz:
https://doaj.org/article/005d7f1526574b5bb017553fc3f6c4ac
Autor:
Stéphane Bernatchez, Christine MacKinnon-Roy, Myriam Hill, Renaud Vincent, Dharani D. Das, Abdelhamid Sayari, Prem Kumarathasan, Dalibor Breznan
Publikováno v:
ACS Nano. 12:12062-12079
Nanoforms of mesoporous silica (mSiNPs) are increasingly applied in medicine, imaging, energy storage, catalysis, biosensors, and bioremediation. The impact of their physicochemical properties on health and the environment remain to be elucidated. In
Autor:
Marianne Ariganello, Fred Elisma, Aziz Khanchi, Prem Kumarathasan, Christine MacKinnon-Roy, Dalibor Breznan, Renaud Vincent, Dharani Das
Publikováno v:
Journal of Applied Toxicology. 38:1302-1315
Knowledge of biological reactivity and underlying toxicity mechanisms of airborne particulate matter (PM) is central to the characterization of the risk associated with these pollutants. An integrated screening platform consisting of protein profilin
Autor:
Renaud Vincent, Mandy Fisher, William D. Fraser, Prem Kumarathasan, Erica Blais, Agnieszka Bielecki, Ajoy Basak, Felicia Au, Tye E. Arbuckle, Sabit Cakmak, James Gomes
Publikováno v:
Chemosphere. 159:506-515
While it is known that in utero exposure to environmental toxicants, namely heavy metals, can adversely affect the neonate, there remains a significant paucity of information on maternal biological changes specific to metal exposures during pregnancy
Publikováno v:
ISEE Conference Abstracts. 2018
Publikováno v:
International Journal of Peptides
Although saliva endothelins are emerging as valuable noninvasive cardiovascular biomarkers, reports on the relationship between isoforms in saliva and plasma remain scarce. We measured endothelins in concurrent saliva and plasma samples (n=30 males;
Autor:
Julie S. O’Brien, Nimal DeSilva, Ngoc Q. Vuong, Stéphane Bernatchez, Surendra Nimesh, Christine MacKinnon-Roy, Prem Kumarathasan, Dalibor Breznan, Myriam Hill, Renaud Vincent, Dharani Das
Publikováno v:
Nanotoxicology. 11(2)
The likelihood of environmental and health impacts of silicon dioxide nanoparticles (SiNPs) has risen, due to their increased use in products and applications. The biological potency of a set of similarly-sized amorphous SiNPs was investigated in a v
Autor:
Prem Kumarathasan, Yong Yang, Dalibor Breznan, Surendra Nimesh, Dharani Das, Myriam Hill, Renaud Vincent, Stéphane Bernatchez, Julie S. O’Brien, Abdelhamid Sayari
Publikováno v:
Journal of Nanomaterials. 2014:1-12
There exists a knowledge gap in understanding potential toxicity of mesoporous silica nanoparticles. A critical step in assessing toxicity of these particles is to have a wide size range with different chemistries and physicochemical properties. Ther