Zobrazeno 1 - 10
of 784
pro vyhledávání: '"Preiss–Handler pathway"'
Autor:
Arif Hasan, Takeshi Marumo, Mami Obara, Sachilo Sato, Yukiko Kondo, Shiniachi Murase, Eichi Taira
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:1-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c527d9d1eb0028c9ab288418d5a6e95
https://doi.org/10.1254/jpssuppl.96.0_1-b-p-051
https://doi.org/10.1254/jpssuppl.96.0_1-b-p-051
Autor:
Nils W. F. Meijer, Johan Gerrits, Susan Zwakenberg, Fried J. T. Zwartkruis, Nanda M. Verhoeven-Duif, Judith J. M. Jans
Publikováno v:
Metabolites, Vol 13, Iss 12, p 1196 (2023)
NAD synthetase 1 (encoded by the gene NADSYN1) is a cytosolic enzyme that catalyzes the final step in the biosynthesis of nicotinamide adenine dinucleotide (NAD+) from tryptophan and nicotinic acid. NADSYN1 deficiency has recently been added to the s
Externí odkaz:
https://doaj.org/article/9e00fe961e6c47efa16164d992d87e11
Autor:
Xinhui Liu, Denggui Luo, Shiying Huang, Siqi Liu, Bing Zhang, Fochang Wang, Jiandong Lu, Jianping Chen, Shunmin Li
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Chronic kidney disease (CKD) is a global public health problem with high morbidity and mortality. Decreased nicotinamide adenine dinucleotide (NAD+) levels were found to be associated with aging, cancer, and neurodegenerative and metabolic disorders.
Externí odkaz:
https://doaj.org/article/f01c0119db7843d0b590dd9ca402a78f
Autor:
Jorge Franco, Francesco Piacente, Melanie Walter, Simone Fratta, Moustafa Ghanem, Andrea Benzi, Irene Caffa, Alexander V. Kurkin, Andrea Altieri, Patrick Herr, Macarena Martínez-Bailén, Inmaculada Robina, Santina Bruzzone, Alessio Nencioni, Alberto Del Rio
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 855 (2022)
NAPRT, the rate-limiting enzyme of the Preiss–Handler NAD biosynthetic pathway, has emerged as a key biomarker for the clinical success of NAMPT inhibitors in cancer treatment. Previous studies found that high protein levels of NAPRT conferred resi
Externí odkaz:
https://doaj.org/article/3955bfbf6c32440698b24b3e27358897
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
The Preiss-Handler pathway, which salvages nicotinate (NA) for NAD synthesis, is a conserved biochemical pathway in land plants. We previously demonstrated that various NA conjugations (mainly methylation and glycosylation) shared the NA detoxificati
Externí odkaz:
https://doaj.org/article/735b747b599b413398d66df60bed9592
Akademický článek
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Publikováno v:
Frontiers in Plant Science, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/49705b5233f541f3a0cd5dfe9a051e31
Autor:
Di Emidio, Giovanna1 giovanna.diemidio@univaq.it, Vergara, Teresa1, Konstantinidou, Fani2,3, Flati, Irene4, Stuppia, Liborio2,3, Artini, Paolo Giovanni5, Gatta, Valentina2,3, Falone, Stefano1, Tatone, Carla1
Publikováno v:
Aging & Disease. Nov2024, Vol. 15 Issue 6, p2828-2851. 24p.
Autor:
Ada Serena Marletta, Alberto Massarotti, Giuseppe Orsomando, Giulio Magni, Menico Rizzi, Silvia Garavaglia
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 419-428 (2015)
Nicotinic acid phosphoribosyltransferase (EC 2.4.2.11) (NaPRTase) is the rate‐limiting enzyme in the three‐step Preiss–Handler pathway for the biosynthesis of NAD. The enzyme catalyzes the conversion of nicotinic acid (Na) and 5‐phosphoribosy
Externí odkaz:
https://doaj.org/article/22745da4fbb14ee191d1014ab8277f75
Autor:
Li, Cunyuan, Liu, Kaiping, Gu, Chengxiang, Li, Ming, Zhou, Ping, Chen, Linxing, Sun, Shize, Li, Xiaoyue, Wang, Limin, Ni, Wei, Li, Meng, Hu, Shengwei
Publikováno v:
Microbiome; 12/20/2024, Vol. 12 Issue 1, p1-14, 14p