α-Tocopherol Long-Chain Metabolite α-T-13'-COOH Exhibits Biphasic Effects on Cell Viability, Induces ROS-Dependent DNA Damage, and Modulates Redox Status in Murine RAW264.7 Macrophages.

Autor: Liao S; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Germany., Börmel L; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Germany., Müller AK; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Germany., Gottschalk L; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany., Pritsch N; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany., Preisner LZ; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany., Samokhina O; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany., Schwarz M; Department of Nutritional Physiology, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany., Kipp AP; Department of Nutritional Physiology, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany., Schlörmann W; Department of Applied Nutritional Toxicology, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany., Glei M; Department of Applied Nutritional Toxicology, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany., Schubert M; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Germany., Schmölz L; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Germany.; Member of Leibniz Research Alliance, Leibniz Health Technology and Leibniz Centre for Photonics in Infection Research, Leibniz Institute of Photonic Technology, Jena, Germany., Wallert M; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Germany., Lorkowski S; Department of Nutritional Physiology and Biochemistry, Institute of Nutritional Sciences, Friedrich Schiller University Jena, Jena, Germany.; Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Germany.

Publikováno v: Molecular nutrition & food research [Mol Nutr Food Res] 2024 Nov 16, pp. e2400455. Date of Electronic Publication: 2024 Nov 16.