Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Preety Panwar"'
Autor:
Preety Panwar, Jacob Bastholm Olesen, Galia Blum, Jean-Marie Delaisse, Kent Søe, Dieter Brömme
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cathepsin K (CatK), an essential collagenase in osteoclasts (OCs), is a potential therapeutic target for the treatment of osteoporosis. Using live-cell imaging, we monitored the bone resorptive behaviour of OCs during dose-dependent inhibiti
Externí odkaz:
https://doaj.org/article/92cb3c72ac144f1391fde56b99a57085
Autor:
Simon Law, Preety Panwar, Jody Li, Adeleke H Aguda, Andrew Jamroz, Rafael V C Guido, Dieter Brömme
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186869 (2017)
Cathepsin K (CatK) is a cysteine protease that plays an important role in mammalian intra- and extracellular protein turnover and is known for its unique and potent collagenase activity. Through studies on the mechanism of its collagenase activity, s
Externí odkaz:
https://doaj.org/article/b8e1c750eb84499aa628571486395374
Publikováno v:
International Journal of Nanomedicine, Vol 2010, Iss default, Pp 101-108 (2010)
Preety Panwar1, Bhumika Pandey1, P C Lakhera2, K P Singh11Biophysics and Nanotechnology Research Laboratory, CBSH, G.B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India; 2Department of Biotechnology, H.N.B. Garhwal Univers
Externí odkaz:
https://doaj.org/article/9bb0714700274a54a7f791aa2c66f56b
Autor:
Baleeswaraiah Muchharla, Brianna Barbee, Marlon Darby, Wei Cao, Hani Elsayed–Ali, Kishor Kumar Sadasivuni, Adetayo Adedeji, Kapil Kumar, Abdennaceur Karoui, Preety Panwar, Gymama Slaughter, Bijandra Kumar
Publikováno v:
Materials Today Communications. 35:106286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd0ecacac9de0739a83901307c02a519
https://doi.org/10.1016/j.mtcomm.2023.106286
https://doi.org/10.1016/j.mtcomm.2023.106286
Autor:
Patrick Graff, Jenny Wilzopolski, Anne Voss, Travis M. Blimkie, January Weiner, Olivia Kershaw, Preety Panwar, Tillie Hackett, Dieter Brömme, Lucie Loyal, Andreas Thiel, Dieter Beule, Robert E.W. Hancock, Achim D. Gruber, Wolfgang Bäumer, Sarah Hedtrich
The development of atopic dermatitis (AD) in infancy, and subsequent allergic rhinitis, food allergies, and asthma in later childhood, is known as the atopic march. The mechanism is largely unknown, yet the course of disease indicates the contributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792f17a055b2f3ca2fad21b828610332
https://doi.org/10.1101/2022.01.17.22269397
https://doi.org/10.1101/2022.01.17.22269397
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Elastin plays an important role in maintaining blood vessel integrity. Proteolytic degradation of elastin in the vascular system promotes the development of atherosclerosis, including blood vessel calcification. Cysteine cathepsins have been implicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5ee6e32bfbfd0c424551d44035d336
http://link.springer.com/article/10.1038/s41598-019-45918-1
http://link.springer.com/article/10.1038/s41598-019-45918-1
Autor:
Dieter Brömme, Xin Du, Preety Panwar, Michel Roberge, Simon Law, Tom A. Pfeifer, Nicolette S. Honson
Publikováno v:
Biochemical Journal. 476:499-512
Cathepsin K (CatK) is a cysteine protease and drug target for skeletal disorders that is known for its potent collagenase and elastase activity. The formation of oligomeric complexes of CatK in the presence of glycosaminoglycans has been associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764d553d658253903d0c1603f2b0cc01
https://doi.org/10.1042/bcj20180851
https://doi.org/10.1042/bcj20180851
Autor:
Christian E.H. Schmelzer, Andrea Heinz, Preety Panwar, David J. Granville, Pierre-Marie Andrault, Wolfgang Hoehenwarter, Tobias Hedtke, Dieter Brömme
Background Skin ageing is associated with structure-functional changes in the extracellular matrix, which is in part caused by proteolytic degradation. Since cysteine cathepsins are major matrix protein-degrading proteases, we investigated the age-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8651b55bfbb83969de1b987e5c04124d
https://publica.fraunhofer.de/handle/publica/262432
https://publica.fraunhofer.de/handle/publica/262432
Autor:
Marco A. Ciufolini, Simon Law, Dieter Brömme, Pouya Azizi, Andrew Jamroz, Preety Panwar, Dongwei Zhang
Publikováno v:
British Journal of Pharmacology. 175:902-923
BACKGROUND AND PURPOSE Attempts to generate active site-directed cathepsin K (CatK) inhibitors for the treatment of osteoporosis have failed because of side effects. We have previously shown that an ectosteric tanshinone CatK inhibitor isolated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85d2de4a32cc9fd39d953a7b28e3548a
https://doi.org/10.1111/bph.14133
https://doi.org/10.1111/bph.14133
Autor:
Preety Panwar, Raquel Viana Rodrigues, Marcelo Giannini, Fernanda Miori Pascon, Dieter Brömme, Ricardo Marins Carvalho, Adriana Pigozzo Manso
Publikováno v:
Dental Materials. 33:1093-1102
Objective To investigate the effects of conditioning solutions containing ferric chloride (FeCl3) on resin–dentin bond strength; on protection of dentin collagen against enzymatic degradation and on cathepsin-K (CT-K) activity. Methods Conditioning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7eb4a8f81e50ccce985c05ac0cf491
https://doi.org/10.1016/j.dental.2017.07.004
https://doi.org/10.1016/j.dental.2017.07.004