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Bioequivalence study of cyclizine hydrochloride 50 mg tablets in healthy volunteers: a randomized, open-label, single-dose study

Autor: Dhiraj Abhyankar, Milind Gole, Preeti Raut, Ashish Shedage

Publikováno v: Therapeutic Delivery. 7:545-551

Background: Cyclizine is used in the treatment and prevention of nausea and vomiting. We aimed to demonstrate bioequivalence between two formulations of cyclizine 50 mg tablets. Methods/Results: This single-dose, two-treatment, two-period, two-sequen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f15c4876a03444c01fc7bfba074539
https://doi.org/10.4155/tde-2016-0023

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Pharmacokinetics of fixed-dose combination of tenofovir disoproxil fumarate, lamivudine, and efavirenz: results of a randomized, crossover, bioequivalence study

Autor: Dhiraj Abhyankar, Ashish Shedage, Preeti Raut, Milind Gole

Publikováno v: International Journal of STD & AIDS. 28:491-498

The objective of this study was to assess the bioequivalence between a fixed-dose combination of tenofovir disoproxil fumarate/lamivudine/efavirenz 300/300/600 mg and the individual innovator products. A randomized, balanced, open-label, two-sequence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8541a080fccc3b128ee59a1bc7e912e
https://doi.org/10.1177/0956462416655955

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Thermosensitive PLA based nanodispersion for targeting brain tumor via intranasal route

Autor: Shruti S. Shikhande, Peeyush N. Goel, S. M. Patil, Amrita N. Bajaj, Darshana S. Jain, Rajani B. Athawale, Rajiv P. Gude, Preeti Raut, Abhijeet Pandey

Publikováno v: Materials Science and Engineering: C. 63:411-421

Delivery of drugs to the brain via nasal route has been studied by many researchers. However, low residence time, mucociliary clearance and enzymatically active environment of nasal cavity pose many challenges to successful nasal delivery of drugs. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48245f425b223e15c041976ef8d4f0ff
https://doi.org/10.1016/j.msec.2016.03.015

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Surface-coated PLA nanoparticles loaded with temozolomide for improved brain deposition and potential treatment of gliomas: development, characterization and in vivo studies

Autor: Amrita N. Bajaj, Peeyush N. Goel, Yuvraj Nikam, S. M. Patil, Shruti Shrikhande, Rajani B. Athawale, Darshana S. Jain, Preeti Raut, Rajiv P. Gude

Publikováno v: Drug Delivery. 23:989-1006

Hydrophobicity of PLA nanoparticles makes them a good substrate for macrophageal and reticulo-endothelial system uptake. Long-circulating properties can be imparted to these particles by coating them with hydrophilic stabilizers. Surface-modified PLA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b0220464892141b6550c53dadc4c0e
https://doi.org/10.3109/10717544.2014.926574

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Application of Quality by Design: Development to Manufacturing of Diclofenac Sodium Topical Gel

Autor: Preeti Raut, Aruna Khanolkar, Viraj Thorat, Gautam Samanta

Publikováno v: AAPS PharmSciTech. 18(7)

The objective of the present study was to develop and optimize generic topical gel formulation of diclofenac sodium through quality by design approaches. The quality target product profile was set for the critical quality attributes of the gel. The k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76590320a8822ee3d5d0d966e0737b4d
https://pubmed.ncbi.nlm.nih.gov/28353174

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