Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Preeti Kanikarla"'
Autor:
Preeti Kanikarla Marie, Alexey V. Sorokin, Lea A. Bitner, Rebecca Aden, Michael Lam, Ganiraju Manyam, Melanie N. Woods, Amanda Anderson, Anna Capasso, Natalie Fowlkes, Michael J. Overman, David G. Menter, Scott Kopetz
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Designing studies of immunotherapy is limited due to a lack of pre-clinical models that reliably predict effective immunotherapy responses. To address this gap, we developed humanized mouse models of colorectal cancer (CRC) incorporating patient-deri
Externí odkaz:
https://doaj.org/article/ec06ee797f544d198959a8dcc024cd38
Autor:
Jennifer S. Davis, Preeti Kanikarla-Marie, Mihai Gagea, Patrick L. Yu, Dexing Fang, Manu Sebastian, Peiying Yang, Ernest Hawk, Roderick Dashwood, Lenard M. Lichtenberger, David Menter, Scott Kopetz
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin and sulindac are effective for colorectal cancer prevention in humans and some animal models, but concerns over gastro-intestinal (GI) ulceration and bleeding limit th
Externí odkaz:
https://doaj.org/article/07034839c3374383bc326e0044408395
Autor:
Preeti Kanikarla Marie, Natalie W. Fowlkes, Vahid Afshar-Kharghan, Stephanie L. Martch, Alexey Sorokin, John Paul Shen, Van K. Morris, Arvind Dasari, Nancy You, Anil K. Sood, Michael J. Overman, Scott Kopetz, David George Menter
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Both platelets and the liver play important roles in the processes of coagulation and innate immunity. Platelet responses at the site of an injury are rapid; their immediate activation and structural changes minimize the loss of blood. The majority o
Externí odkaz:
https://doaj.org/article/d372e71f7a2f40a79c386cc5ab8f208d
Autor:
Geetali Pradhan, Chia-Shan Wu, Jong Han Lee, Preeti Kanikarla, Shaodong Guo, Vijay K. Yechoor, Susan L. Samson, Yuxiang Sun
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Orexigenic hormone ghrelin and anorexic hormone obestatin are encoded by the same preproghrelin gene. While it is known that ghrelin inhibits glucose-stimulated insulin secretion (GSIS), the effect of obestatin on GSIS is unclear. Ghrelin’
Externí odkaz:
https://doaj.org/article/1b735f08e0564ebead1027bd8a844987
Autor:
Preeti Kanikarla-Marie, Sushil K. Jain
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 6, Pp 2160-2170 (2015)
Background/Aims: Type 1 diabetic (T1D) patients have a higher incidence of liver disease. T1D patients frequently experience elevated plasma ketone levels along with hyperglycemia. However, no study has examined whether hyperketonemia per se has any
Externí odkaz:
https://doaj.org/article/c4c49da66d7848e894765ff4b1454377
Autor:
Preeti Kanikarla-Marie, Michael Lam, Alexey V. Sorokin, Michael J. Overman, Scott Kopetz, David G. Menter
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The role of platelets in cancer progression has been well recognized in the field of cancer biology. Emerging studies are elaborating further the additional roles and added extent that platelets play in promoting tumorigenesis. Platelets release fact
Externí odkaz:
https://doaj.org/article/d526b310b85841d792f3a1cfbb891a49
Autor:
Preeti Kanikarla-Marie, Sushil K. Jain
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 1, Pp 364-373 (2015)
Background/Aims: The incidence of developing microvascular dysfunction is significantly higher in type 1 diabetic (T1D) patients. Hyperketonemia (acetoacetate, β-hydroxybutyrate) is frequently found along with hyperglycemia in T1D. Whether hyperketo
Externí odkaz:
https://doaj.org/article/d96ed511229a40de8aad36f6faa3a656
Autor:
Alexey V. Sorokin, Preeti Kanikarla Marie, Lea Bitner, Muddassir Syed, Melanie Woods, Ganiraju Manyam, Lawrence N. Kwong, Benny Johnson, Van K. Morris, Philip Jones, David G. Menter, Michael S. Lee, Scott Kopetz
Publikováno v:
Cancer Research. 82:3335-3344
KRAS and NRAS mutations occur in 45% of colorectal cancers, with combined MAPK pathway and CDK4/6 inhibition identified as a potential therapeutic strategy. In the current study, this combinatorial treatment approach was evaluated in a co-clinical tr
Autor:
Stefania Napolitano, Melanie Woods, Hey Min Lee, Vincenzo De Falco, Giulia Martini, Carminia Maria Della Corte, Erika Martinelli, Vincenzo Famiglietti, Davide Ciardiello, Amanda Anderson, Natalie Wall Fowlkes, Oscar Eduardo Villareal, Alexey Sorokin, Preeti Kanikarla, Olu Coker, Van Morris, Lucia Altucci, Josep Tabernero, Teresa Troiani, Fortunato Ciardiello, Scott Kopetz
Publikováno v:
Scientia
Purpose: Encorafenib + cetuximab (E+C) is an effective therapeutic option in chemorefractory BRAFV600E metastatic colorectal cancer (mCRC). However, there is a need to improve the efficacy of this molecular-targeted therapy and evaluate regimens suit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206f53de24b61dea932f3c6f45b9c5eb
https://hdl.handle.net/11351/9975
https://hdl.handle.net/11351/9975
Autor:
Scott Kopetz, Fortunato Ciardiello, Teresa Troiani, Josep Tabernero, Lucia Altucci, Van Morris, Olu Coker, Preeti Kanikarla, Alexey Sorokin, Oscar Eduardo Villareal, Natalie Wall Fowlkes, Amanda Anderson, Davide Ciardiello, Vincenzo Famiglietti, Erika Martinelli, Carminia Maria Della Corte, Giulia Martini, Vincenzo De Falco, Hey Min Lee, Melanie Woods, Stefania Napolitano
Purpose:Encorafenib + cetuximab (E+C) is an effective therapeutic option in chemorefractory BRAFV600E metastatic colorectal cancer (mCRC). However, there is a need to improve the efficacy of this molecular-targeted therapy and evaluate regimens suita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b618c2bf453962a0c85958a1222f81a3
https://doi.org/10.1158/1078-0432.c.6618070.v1
https://doi.org/10.1158/1078-0432.c.6618070.v1