Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Preeti J. Muire"'
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Background Delayed fracture healing caused by soft tissue loss can be resolved by the administration of a Th1 immunosuppressant, such as FK506. Additionally, open fractures are at high risk for infection. We hypothesized that the inclusion o
Externí odkaz:
https://doaj.org/article/2e49702bb694405d84c8bb9a00c4d20b
Autor:
Michael E. Whitely, Sarah M. Helms, Preeti J. Muire, Alicia L. Lofgren, Rebecca A. Lopez, Joseph C. Wenke
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-8 (2022)
Abstract Background Treatment of open fractures remains a significant challenge in trauma care as these fractures are accompanied by extensive soft tissue damage, exposing the wound site to contaminants and increasing infection risk. Formation of bio
Externí odkaz:
https://doaj.org/article/e5815c1a60aa45c9972c5740292893d0
Publikováno v:
Journal of Experimental Orthopaedics, Vol 10, Iss 1, Pp n/a-n/a (2023)
Abstract Purpose The mitochondrial DNA (mtDNA) activated cyclic guanosine monophosphate–adenosine monophosphate synthase—stimulator of interferon genes (cGAS‐STING) signaling pathway is a key player in mediating immune responses in autoimmune d
Externí odkaz:
https://doaj.org/article/4071753f1e47431b8b84365533316a62
Publikováno v:
Journal of Experimental Orthopaedics, Vol 9, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose Delayed fracture healing is a common consequence of polytrauma (PT) occurring in patients with multiple injuries. We believe that when early release of high mobility group box 1 (HMGB1) molecules from necrotic tissues exceed their no
Externí odkaz:
https://doaj.org/article/adb70550f0b74debb9084e70db5e7a96
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Single trauma injuries or isolated fractures are often manageable and generally heal without complications. In contrast, high-energy trauma results in multi/poly-trauma injury patterns presenting imbalanced pro- and anti- inflammatory responses often
Externí odkaz:
https://doaj.org/article/aa5c697ef1de4cf689fa8296f2545d2b
Publikováno v:
Cells, Vol 10, Iss 7, p 1646 (2021)
We previously reported an early surge in high mobility group box protein 1 (HMGB1) levels in a polytrauma (PT) rat model. This study investigates the association of HMGB1 levels in mediating PT associated dysregulated immune responses and its influen
Externí odkaz:
https://doaj.org/article/dad9d9f066544a8e869431fefbde2440
Publikováno v:
International journal of molecular sciences. 23(8)
Delayed healing of traumatic wounds often stems from a dysregulated immune response initiated or exacerbated by existing comorbidities, multiple tissue injury or wound contamination. Over decades, approaches towards alleviating wound inflammation hav
Publikováno v:
Journal of experimental orthopaedics. 9(1)
Delayed fracture healing is a common consequence of polytrauma (PT) occurring in patients with multiple injuries. We believe that when early release of high mobility group box 1 (HMGB1) molecules from necrotic tissues exceed their normal levels in bl
Autor:
Veera Gnaneswar Gude, Preeti J. Muire
Publikováno v:
Sustainable Cities and Society
Highlights • Discussed economic impact of water utilities and COVID-19 health impacts on workforce. • Presented case studies on preparedness and response to COVID-19 by utilities. • Reviewed alternate resiliency strategies for response during a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Single trauma injuries or isolated fractures are often manageable and generally heal without complications. In contrast, high-energy trauma results in multi/poly-trauma injury patterns presenting imbalanced pro- and anti- inflammatory responses often