Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Preeti J. Muire"'
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Background Delayed fracture healing caused by soft tissue loss can be resolved by the administration of a Th1 immunosuppressant, such as FK506. Additionally, open fractures are at high risk for infection. We hypothesized that the inclusion o
Externí odkaz:
https://doaj.org/article/2e49702bb694405d84c8bb9a00c4d20b
Autor:
Michael E. Whitely, Sarah M. Helms, Preeti J. Muire, Alicia L. Lofgren, Rebecca A. Lopez, Joseph C. Wenke
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-8 (2022)
Abstract Background Treatment of open fractures remains a significant challenge in trauma care as these fractures are accompanied by extensive soft tissue damage, exposing the wound site to contaminants and increasing infection risk. Formation of bio
Externí odkaz:
https://doaj.org/article/e5815c1a60aa45c9972c5740292893d0
Publikováno v:
Journal of Experimental Orthopaedics, Vol 10, Iss 1, Pp n/a-n/a (2023)
Abstract Purpose The mitochondrial DNA (mtDNA) activated cyclic guanosine monophosphate–adenosine monophosphate synthase—stimulator of interferon genes (cGAS‐STING) signaling pathway is a key player in mediating immune responses in autoimmune d
Externí odkaz:
https://doaj.org/article/4071753f1e47431b8b84365533316a62
Publikováno v:
Journal of Experimental Orthopaedics, Vol 9, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose Delayed fracture healing is a common consequence of polytrauma (PT) occurring in patients with multiple injuries. We believe that when early release of high mobility group box 1 (HMGB1) molecules from necrotic tissues exceed their no
Externí odkaz:
https://doaj.org/article/adb70550f0b74debb9084e70db5e7a96
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Single trauma injuries or isolated fractures are often manageable and generally heal without complications. In contrast, high-energy trauma results in multi/poly-trauma injury patterns presenting imbalanced pro- and anti- inflammatory responses often
Externí odkaz:
https://doaj.org/article/aa5c697ef1de4cf689fa8296f2545d2b
Publikováno v:
Cells, Vol 10, Iss 7, p 1646 (2021)
We previously reported an early surge in high mobility group box protein 1 (HMGB1) levels in a polytrauma (PT) rat model. This study investigates the association of HMGB1 levels in mediating PT associated dysregulated immune responses and its influen
Externí odkaz:
https://doaj.org/article/dad9d9f066544a8e869431fefbde2440
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184077 (2017)
In the absence of lymphocytes, rag1-/- mutant zebrafish develop protective immunity to bacteria. In mammals, induction of protection by innate immunity can be mediated by macrophages or natural killer (NK) cells. To elucidate potential responsive cel
Externí odkaz:
https://doaj.org/article/1e4af9e72216481e92a268b30ecc7b80
Publikováno v:
International journal of molecular sciences. 23(8)
Delayed healing of traumatic wounds often stems from a dysregulated immune response initiated or exacerbated by existing comorbidities, multiple tissue injury or wound contamination. Over decades, approaches towards alleviating wound inflammation hav
Publikováno v:
Journal of experimental orthopaedics. 9(1)
Delayed fracture healing is a common consequence of polytrauma (PT) occurring in patients with multiple injuries. We believe that when early release of high mobility group box 1 (HMGB1) molecules from necrotic tissues exceed their normal levels in bl
Autor:
Veera Gnaneswar Gude, Preeti J. Muire
Publikováno v:
Sustainable Cities and Society
Highlights • Discussed economic impact of water utilities and COVID-19 health impacts on workforce. • Presented case studies on preparedness and response to COVID-19 by utilities. • Reviewed alternate resiliency strategies for response during a