Výsledky vyhledávání - "Preethy Paul"

Plasma Protein Binding of Anisomelic Acid: Spectroscopy and Molecular Dynamic Simulations

Autor: Mark S. Johnson, Parthiban Marimuthu, Rajendran Senthilkumar, Yesaiyan Manojkumar, John E. Eriksson, Sankaralingam Arunachalam, Preethy Paul

Publikováno v: Journal of Chemical Information and Modeling. 56:2401-2412

Anisomelic acid (AA) is a macrocyclic cembranolide compound extracted from Anisomeles herbal species. Recently, we have shown that AA possesses both anticancer and antiviral activity. However, to date, the plasma protein binding properties of AA are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efee9f223bfa996b89b535cc622af780
https://doi.org/10.1021/acs.jcim.6b00445

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Targeted delivery of a novel anticancer compound anisomelic acid using chitosan-coated porous silica nanorods for enhancing the apoptotic effect

Autor: Magnus Odén, John E. Eriksson, Rajendran Senthilkumar, Emma M. Björk, Didem Şen Karaman, Preethy Paul, Jessica M. Rosenholm

Publikováno v: Biomaterials Science. 3:103-111

Targeted cancer therapies are currently a strong focus in biomedical research. The most common approach is to use nanocarrier-based targeting to specifically deliver conventional anticancer drugs to enhance their therapeutic efficacy, increase bioava

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https://doi.org/10.1039/c4bm00278d

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PRESCRIBING PATTERN OF DRUGS IN PREGNANT WOMEN ATTENDING ANTENATAL OUTPATIENT DEPARTMENT OF A TERTIARY CARE TEACHING HOSPITAL

Autor: Athira Raju, Preethy Paul

Drug treatment during pregnancy presents a special concern. Pharmacoepidemiological studies can measure the extent of prescription and teratogenic drug use in pregnant women. Objective: To understand the prescribing trends &pharmacological class wise

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Protein binding and biological evaluation of a polymer-anchored cobalt(iii) complex containing a 2,2′-bipyridine ligand

Autor: Vaiyapuri Subbarayan Periasamy, Rajendran Senthilkumar, Sankaralingam Arunachalam, Mohammad Abdulkadher Akbarsha, Preethy Paul, G. Vignesh

Publikováno v: RSC Adv.. 4:57483-57492

The molecular interaction of polymer-anchored cobalt(III) complex, cis-[Co(bpy)2(BPEI)Cl]Cl2·4H2O (bpy = 2,2′-bipyridine, BPEI = branched polyethyleneimine) with two plasma proteins, human serum albumin (HSA) and bovine serum albumin (BSA) using v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14f98460794b965bed5e8bed24df32a0
https://doi.org/10.1039/c4ra10377g

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Novel action modality of the diterpenoid anisomelic acid causes depletion of E6 and E7 viral oncoproteins in HPV-transformed cervical carcinoma cells

Autor: Emilia Peuhu, Sakari Hietanen, Mohammad Abdulkader Akbarsha, Senthil Kumar Rajendran, John E. Eriksson, Ali A. Alshatwi, Preethy Paul

Publikováno v: Biochemical Pharmacology. 89(2):171-184

Cervical cancer, the second most common malignancy among women, is mainly caused by human papilloma virus (HPV) infection. In HPV-positive cervical cancer cells, the activity of p53 and the induction of p21 are inhibited by the HPV oncoproteins E6 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a179525a6b203353b87e82d4eee24483
https://doi.org/10.1016/j.bcp.2014.02.011

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The antitumor lignan Nortrachelogenin sensitizes prostate cancer cells to TRAIL-induced cell death by inhibition of the Akt pathway and growth factor signaling

Autor: Emilia Peuhu, Patrik Eklund, Mika Remes, John E. Eriksson, Rainer Sjöholm, Thomas Holmbom, Preethy Paul

Publikováno v: Biochemical Pharmacology. 86:571-583

Prostate cancer cells frequently develop resistance toward androgen-deprivation and chemotherapy. To identify new approaches to treat androgen-dependent prostate cancer, we have performed a structure-activity analysis of lignan polyphenols for cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bf2ed890051a744cc3e766e91d5c12
https://doi.org/10.1016/j.bcp.2013.05.026

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Cytotoxic effect of a polymer–copper(II) complex containing 2,2′-bipyridyl ligand on human lung cancer cells

Autor: Vaiyapuri Subbarayan Periasamy, Mohammad Abdulkadher Akbarsha, Sankaralingam Arunachalam, C. Preethy Paul, R. Senthil Kumar, Anvarbatcha Riyasdeen

Publikováno v: Medicinal Chemistry Research. 20:726-731

The cytotoxic activity of the polymer–copper(II) complex, [Cu(bpy)2(BPEI)]Cl2·4H2O (bpy = 2,2′-bipyridine, BPEI = branched polyethyleneimine) on NCI-H460 human lung cancer cells was determined adopting MTT assay and specific staining techniques.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::873f5d87edb05f47547d1e8c1c6b41f2
https://doi.org/10.1007/s00044-010-9380-8

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Nurse-led epilepsy follow-up clinic in India: is it feasible and acceptable to patients? A pilot study

Autor: Sreenivas Vishnubhatla, Meena Agarwal, Mamta Singh, Rohit Bhatia, Preethy Paul

Publikováno v: Seizure. 23(1)

Purpose India has an epilepsy treatment gap of up to 90%. Shortage of doctors, especially in rural communities makes getting epilepsy treatment almost impossible for the vast majority. Nurses are relatively more in number and available even in smalle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28492510f753970c90aa527ecbb5d48
https://pubmed.ncbi.nlm.nih.gov/24055364

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