Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Preethi Ragunathan"'
Autor:
Preethi Ragunathan, Divya Sridaran, Anja Weigel, Sarah Shabayek, Barbara Spellerberg, Karthe Ponnuraj
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67517 (2013)
Lmb is a 34 kDa laminin binding surface adhesin of Streptococcus agalactiae. The structure of Lmb reported by us recently has shown that it consists of a metal binding crevice, in which a zinc ion is coordinated to three highly conserved histidines.
Externí odkaz:
https://doaj.org/article/8768567b659342ee82212129f28b1d21
Publikováno v:
ACS Omega. 8:7989-8000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4614cbc9d8f4c80a0e49abcb9bfa1431
https://doi.org/10.1021/acsomega.2c07805
https://doi.org/10.1021/acsomega.2c07805
Autor:
Upasana Sridharan, Thirumananseri Kumarevel, Karthe Ponnuraj, Shigeyuki Yokoyama, Preethi Ragunathan, Seiki Kuramitsu
Publikováno v:
Biochemical and Biophysical Research Communications. 547:96-101
Carbonic anhydrases (CA) are the most ubiquitous ancient zinc metalloenzymes known. Here we report the structural and functional analysis of a hypothetical protein GK2848 from Geobacillus kaustophilus. The analysis revealed that it belongs to the γ-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff727ce0c49250f1074bdb28b3dd547
https://doi.org/10.1016/j.bbrc.2021.02.036
https://doi.org/10.1016/j.bbrc.2021.02.036
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:6272-6285
Alternate sigma factors play a major role in the survival of pathogenic bacteria such as Streptococcus pyogenes in adverse environment conditions. Stress induced sigma factors mediate gene expression under conditions of pathogenesis, dormancy and unu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9130b2547182124c10f398a35f122e2
https://doi.org/10.1080/07391102.2021.1882338
https://doi.org/10.1080/07391102.2021.1882338
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 37:714-725
Metal-binding receptors are one of the extracellular components of ATP-binding cassette transporters that are essential for regulation of metal homeostasis in bacteria. Laminin-binding adhesin (Lmb) of Streptococcus agalactiae falls under this class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024cfa1fc8fa81e847f62c39366db98a
https://doi.org/10.1080/07391102.2018.1438923
https://doi.org/10.1080/07391102.2018.1438923
Publikováno v:
RSC Advances. 6:91824-91835
Pneumococcal adherence and virulence factor A (PavA) were first identified in Streptococcus pneumoniae as an adhesin binding to fibronectin and studies suggested that it is an important virulence determinant. Homologs of PavA are found in many Gram-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::238a6f38d962129e432f73f778981bc4
https://doi.org/10.1039/c6ra18275e
https://doi.org/10.1039/c6ra18275e
Autor:
Preethi Ragunathan, Karthe Ponnuraj
Publikováno v:
The Protein Journal. 30:159-166
Streptococcus agalactiae is a leading cause of bacterial sepsis and meningitis in neonates. FbsA, a fibrinogen receptor of S. agalactiae is highly repetitive protein with each repeat containing 16 amino acids. The protein sequence of FbsA shows no ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb830d77d724dad97cd4afaccbc2fd12
https://doi.org/10.1007/s10930-011-9317-1
https://doi.org/10.1007/s10930-011-9317-1
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 25:183-188
Leptin, the ob gene product, is a 167 amino acid polypeptide known to play a key role in regulating the fat stores of the body and is found in all eukaryotes, including mammals, aves, and also in invertebrates. To gain insight into the structure-func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b947f691fe4a038dfe246e5027cfe34e
https://doi.org/10.1080/07391102.2007.10507167
https://doi.org/10.1080/07391102.2007.10507167
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 65:492-494
Laminin-binding protein (Lmb), a surface-exposed lipoprotein from Streptococcus agalactiae (group B streptococcus), mediates attachment to human laminin and plays a crucial role in the adhesion/invasion of eukaryotic host cells. However, the structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584d04ac3c8746efadf101f169c691d9
https://doi.org/10.1107/s1744309109012743
https://doi.org/10.1107/s1744309109012743
Autor:
Karthe Ponnuraj, Preethi Ragunathan, Gokul Raghunath, Thirumananseri Kumarevel, Shigeyuki Yokoyama, Seiki Kuramitsu
Publikováno v:
Acta crystallographica. Section F, Structural biology and crystallization communications. 69(Pt 2)
GK2848, a hypothetical protein from the thermophilic organism Geobacillus kaustophilus, was cloned and overexpressed in Escherichia coli. The protein was purified to homogeneity using Ni-NTA affinity-column and gel-filtration chromatography. The puri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d8082f77c20ec6da7d757176458507
https://pubmed.ncbi.nlm.nih.gov/23385759
https://pubmed.ncbi.nlm.nih.gov/23385759