Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Preethi Mandati"'
Autor:
Sagar Narala, Dinesh Nyavanandi, Preethi Mandati, Ahmed Adel Ali Youssef, Abdullah Alzahrani, Praveen Kolimi, Feng Zhang, Michael Repka
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100156- (2023)
This work developed high drug-load pellets for colon targeting in minimal steps by coupling hot-melt extrusion (HME) with a die-surface cutting pelletizer, offering a potential continuous pellet manufacturing process. Ketoprofen (KTP) was selected as
Externí odkaz:
https://doaj.org/article/cba887c0e9554274982da1e0682ec6d7
Autor:
Dinesh Nyavanandi, Preethi Mandati, Sagar Narala, Abdullah Alzahrani, Praveen Kolimi, Sateesh Kumar Vemula, Michael A. Repka
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2267 (2023)
The current research aims to improve the solubility of the poorly soluble drug, i.e., ibuprofen, by developing self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt granulation (TSMG) approach. Gelucire® 44/14, Gelucire® 48/16,
Externí odkaz:
https://doaj.org/article/a1f0353d263f4908b57f7cca6940acfb
Autor:
Nagarjun Rangaraj, Sunitha Sampathi, Vijayabhaskarreddy Junnuthula, Praveen Kolimi, Preethi Mandati, Sagar Narala, Dinesh Nyavanandi, Sathish Dyawanapelly
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1807 (2022)
Among various drug administration routes, oral drug delivery is preferred and is considered patient-friendly; hence, most of the marketed drugs are available as conventional tablets or capsules. In such cases, the administration of drugs with or with
Externí odkaz:
https://doaj.org/article/f131d57ba1774d20ab5b1635337b51b7
Autor:
Dinesh Nyavanandi, Sagar Narala, Preethi Mandati, Abdullah Alzahrani, Praveen Kolimi, Ahmed Almotairy, Michael A. Repka
Publikováno v:
AAPS PharmSciTech. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::771308698ecaffd60426773df20d7d61
https://doi.org/10.1208/s12249-023-02512-z
https://doi.org/10.1208/s12249-023-02512-z
Autor:
Preethi Mandati, Nagireddy Dumpa, Abdullah Alzahrani, Dinesh Nyavanandi, Sagar Narala, Honghe Wang, Suresh Bandari, Michael A. Repka, Sandip Tiwari, Nigel Langley
Publikováno v:
AAPS PharmSciTech. 24(1)
The main objective of the current research was to investigate the effect of tablet shapes (heart-shaped and round tablets) and infill densities (50% and 100%) on the drug release profiles of 3D printed tablets prepared by hot-melt extrusion paired wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2895c8e85cc463a3b968f77a78504d
https://pubmed.ncbi.nlm.nih.gov/36477554
https://pubmed.ncbi.nlm.nih.gov/36477554
Autor:
Sagar Narala, Neeraja Komanduri, Dinesh Nyavanandi, Ahmed Adel Ali Youssef, Preethi Mandati, Abdullah Alzahrani, Praveen Kolimi, Nagarjuna Narala, Michael A. Repka
Publikováno v:
Journal of Drug Delivery Science and Technology. 82:104384
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc280c2a021c659e9566fd8b9dc23266
https://doi.org/10.1016/j.jddst.2023.104384
https://doi.org/10.1016/j.jddst.2023.104384
Autor:
Abdullah Alzahrani, Sagar Narala, Ahmed Adel Ali Youssef, Dinesh Nyavanandi, Suresh Bandari, Preethi Mandati, Ahmed Almotairy, Mashan Almutairi, Michael Repka
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 177
Fixed-dose combinations (FDCs) achieve optimal goals for treatment with minimal side effects, decreased administration of large number of tablets, thus, greater convenience, and improved patient compliance. However, conventional FDCs do not have a gu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72284dd5857a3f5b8257298ce1bb2e8b
https://pubmed.ncbi.nlm.nih.gov/35835328
https://pubmed.ncbi.nlm.nih.gov/35835328
Autor:
Abdullah Alzahrani, Dinesh Nyavanandi, Preethi Mandati, Ahmed Adel Ali Youssef, Sagar Narala, Suresh Bandari, Michael Repka
Publikováno v:
International journal of pharmaceutics. 624
Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in recent years, with the potential to improve the apparent solubility and, hence, the oral bioavailability of poorly soluble drugs. The process of formulating ASDs is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3d7589e0357df590a21302a0479d27
https://pubmed.ncbi.nlm.nih.gov/35753536
https://pubmed.ncbi.nlm.nih.gov/35753536
Autor:
Dinesh Nyavanandi, Preethi Mandati, Sagar Narala, Abdullah Alzahrani, Praveen Kolimi, Adwait Pradhan, Suresh Bandari, Michael A. Repka
Publikováno v:
International Journal of Pharmaceutics. 628:122283
The development of amorphous solid dispersions (ASDs) of high-melting-point drug substances using hot-melt extrusion (HME) continues to be challenging because of the limited availability of polymers that are stable at high processing temperatures. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebffaf58851b18dd15e87ceec15d5503
https://doi.org/10.1016/j.ijpharm.2022.122283
https://doi.org/10.1016/j.ijpharm.2022.122283
Autor:
Preethi Mandati, Michael A. Repka, Dinesh Nyavanandi, Priyanka Srinivasan, Suresh Bandari, Sagar Narala
Publikováno v:
J Drug Deliv Sci Technol
Enhancing the solubility of active drug ingredients is a major challenge faced by scientists and researchers. Different approaches have been explored for the enhancement of solubility and physicochemical properties of drugs, without affecting their s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e72c8cacdc84fcd7a09f269a0c99bc
https://doi.org/10.1016/j.jddst.2020.102209
https://doi.org/10.1016/j.jddst.2020.102209