Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Preedakorn Chunhacha"'
Autor:
Zin Zin Ei, Kanuengnit Choochuay, Alisa Tubsuwan, Decha Pinkaew, Maneewan Suksomtip, Chanida Vinayanuwattikun, Pithi Chanvorachote, Preedakorn Chunhacha
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Cisplatin (CDDP) induces senescence characterized by senescence-associated secretory phenotypes (SASP) and the unfolded protein response (UPR). In this study, we investigated the proteins related to the UPR during the senescence cell fate. S
Externí odkaz:
https://doaj.org/article/ad6d1a96e493418c8a33cafca4d13c0c
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Heart failure (HF) has reached epidemic proportions in developed countries, affecting over 20 million people worldwide. Despite modern medical and device therapies, 60–70% of HF patients still die within 5 years of diagnosis as it relentle
Externí odkaz:
https://doaj.org/article/f9992a0e71944714947dfcccc820b5a8
Autor:
Nan Yadanar Lin Pyae, Arnatchai Maiuthed, Wongsakorn Phongsopitanun, Bongkot Ouengwanarat, Warongrit Sukma, Nitipol Srimongkolpithak, Jutharat Pengon, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan, Zin Zin Ei, Preedakorn Chunhacha, Patcharin Wilasluck, Peerapon Deetanya, Kittikhun Wangkanont, Kowit Hengphasatporn, Yasuteru Shigeta, Thanyada Rungrotmongkol, Supakarn Chamni
Publikováno v:
Molecules, Vol 28, Iss 3, p 1104 (2023)
New N-containing xanthone analogs of α-mangostin were synthesized via one-pot Smiles rearrangement. Using cesium carbonate in the presence of 2-chloroacetamide and catalytic potassium iodide, α-mangostin (1) was subsequently transformed in three st
Externí odkaz:
https://doaj.org/article/9bb9e41a21844fdcb618b40f9d8f32f2
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2703 (2022)
Cellular senescence is linked with chemotherapy resistance. Based on previous studies, GRP78 is a signal transducer in senescent cells. However, the association between GRP78 and stem cell phenotype remains unknown. Cisplatin treatment was clarified
Externí odkaz:
https://doaj.org/article/341b1cc6b4b64a9daeac6404064c9e66
Autor:
Decha Pinkaew, Abhijnan Chattopadhyay, Matthew D. King, Preedakorn Chunhacha, Zhihe Liu, Heather L. Stevenson, Yanjie Chen, Patuma Sinthujaroen, Owen M. McDougal, Ken Fujise
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
IRE1α is an ER stress sensor, whose activity induces apoptosis. Here, the authors report that fortilin, a pro-survival factor, with yet unknown roles in ER stress, interacts with active IRE1α, inhibits both its kinase end RNase activities, and prot
Externí odkaz:
https://doaj.org/article/41562ffacfaf46d09359e93528290463
Autor:
Hasseri Halim, Decha Pinkaew, Preedakorn Chunhacha, Patuma Sinthujaroen, Perumal Thiagarajan, Ken Fujise
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218934 (2019)
Ticagrelor (TIC), a P2Y purinoceptor 12 (P2Y12)-receptor antagonist, has been widely used to treat patients with acute coronary syndrome. Although animal studies suggest that TIC protects against atherosclerosis, it remains unknown whether it does so
Externí odkaz:
https://doaj.org/article/14a23a02040d488ca3aded95e11faaa5
Autor:
Angkana Tantituvanont, Pacharaporn Jiamchaisri, Preedakorn Chunhacha, Kanittha Pongjit, Chuanpit Ninsontia, Kulwara Meksawan, Boonchoo Sritularak, Pithi Chanvorachote
Publikováno v:
Songklanakarin Journal of Science and Technology (SJST), Vol 37, Iss 2, Pp 155-162 (2015)
Cisplatin mediated nephrotoxicity has been continuously reported and recognized as a major obstacle for cisplatinbased chemotherapy. The present study aimed to demonstrate the potential use of silymarin, an extract from the seed of Silybum marianum
Externí odkaz:
https://doaj.org/article/7837a2d216cc4f27aad08c0c6d5f8e05
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68623 (2013)
The migratory capability of cancer cells is one of the most important hallmarks reflecting metastatic potential. Ouabain, an endogenous cardiac glycoside produced by the adrenal gland, has been previously reported to have anti-tumor activities; howev
Externí odkaz:
https://doaj.org/article/72832d3b3a2b48d4a9c3e9868783d397
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57466 (2013)
The knowledge regarding the role of caveolin-1 (Cav-1) protein on endothelium adhesion of cancer cells is unclear. The present study revealed that Cav-1 plays a negative regulatory role on cancer-endothelium interaction. Endogenous Cav-1 was shown to
Externí odkaz:
https://doaj.org/article/8331b670f57742c696a99fa0515edf32
Autor:
Chavee Laomeephol, Sudartip Areecheewakul, Supannikar Tawinwung, Koramit Suppipat, Preedakorn Chunhacha, Nuno M. Neves, Jittima Amie Luckanagul
Publikováno v:
Nanoscale. 14:17821-17840
Hyaluronic acid-based nanoparticles can be promising tools for gene delivery in in vivo reprogramming CAR T cells, as well-designed carriers are needed for targeting and transducing circulating T cells.