Daily low-dose prednisolone to prevent relapse of steroid-sensitive nephrotic syndrome in children with an upper respiratory tract infection: PREDNOS2 RCT

Autor: Martin T Christian, Nicholas JA Webb, Rebecca L Woolley, Nafsika Afentou, Samir Mehta, Emma Frew, Elizabeth A Brettell, Adam R Khan, David V Milford, Detlef Bockenhauer, Moin A Saleem, Angela S Hall, Ania Koziell, Heather Maxwell, Shivaram Hegde, Eric R Finlay, Rodney D Gilbert, Caroline Jones, Karl McKeever, Wendy Cook, Natalie Ives

Publikováno v: Health Technology Assessment, Vol 26, Iss 3 (2022)
Christian, M T, Webb, N J, Woolley, R L, Afentou, N, Mehta, S, Frew, E, Brettell, E A, Khan, A R, Milford, D V, Bockenhauer, D, Saleem, M A, Hall, A S, Koziell, A, Maxwell, H, Hegde, S, Finlay, E R, Gilbert, R D, Jones, C, McKeever, K, Cook, W & Ives, N 2022, ' Daily low-dose prednisolone to prevent relapse of steroid-sensitive nephrotic syndrome in children with an upper respiratory tract infection : PREDNOS2 RCT ', Health Technology Assessment, vol. 26, no. 3, pp. i-93 . https://doi.org/10.3310/WTFC5658

Background Most children with steroid-sensitive nephrotic syndrome have relapses that are triggered by upper respiratory tract infections. Four small trials, mostly in children already taking maintenance corticosteroid in countries of different upper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17aee7fb6adb33e40b9e7ab40987fa8
https://doi.org/10.3310/wtfc5658

Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose 2 trial

Autor: Schaik, M. van, Arends, E.J., Soonawala, D., Ommen, E. van, Leeuw, K. de, Limper, M., Paassen, P. van, Huizinga, T.W.J., Toes, R.E.M., Kooten, C. van, Rotmans, J.I., Rabelink, T.J., Teng, Y.K.O.

Publikováno v: Trials, 23
Trials, 23, 1
Trials, 23(1):939. BioMed Central Ltd
TRIALS, 23(1):939. BMC
Trials, 23(1). BMC

Background Belimumab, an anti-B-cell activating factor antibody, is approved for the treatment of auto-antibody positive systemic lupus erythematosus with a high degree of disease activity. Anti-CD20 B cell depletion with rituximab is used in refract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70084a3ecb1926a3b2b1879d2380755
http://hdl.handle.net/2066/285290

Interventions for infantile haemangiomas of the skin

Autor: Hector Pardo-Hernandez, Mónica Novoa, A. Shahbaz, Ingrid Arevalo-Rodriguez, Lucia Giraldo, Sandra Beltran, Eulalia Baselga

Publikováno v: Cochrane Database of Systematic Reviews
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
The Cochrane Library

BACKGROUND: Infantile haemangiomas (previously known as strawberry birthmarks) are soft, raised swellings of the skin that occur in 3% to 10% of infants. These benign vascular tumours are usually uncomplicated and tend to regress spontaneously. Howev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfdfde49b4d29668fce58bcd87fa1eb
https://pubmed.ncbi.nlm.nih.gov/32173946

Genetic and in vivo determinants of glucocorticoid sensitivity in relation to clinical outcome of childhood nephrotic syndrome

Autor: Jan W. Koper, Nynke Teeninga, Marie C Kersten, Joana E. Kist-van Holthe, Hans G Krabbe, Eric Boersma, Albert J. van der Heijden, Erica L T van den Akker, Jeroen Nauta, Nine V A M Knoers

Publikováno v: Kidney International, 85(6), 1444-1453. ELSEVIER SCIENCE INC
Pediatric Nephrology, 28(8), 1596-1596. Springer
Teeninga, N, van Holthe, J E, van den Akker, E L T, Kersten, M C, Boersma, E, Krabbe, H G, Knoers, N V A M, van der Heijden, A J, Koper, J W & Nauta, J 2014, ' Genetic and in vivo determinants of glucocorticoid sensitivity in relation to clinical outcome of childhood nephrotic syndrome ', Kidney International, vol. 85, no. 6, pp. 1444-1453 . https://doi.org/10.1038/ki.2013.531
Kidney International, 85(6), 1444-1453. Nature Publishing Group

Following initial glucocorticoid treatment, the clinical course in children with nephrotic syndrome is highly variable. Intrinsic sensitivity to glucocorticoids might be a determinant of this variability. Functional polymorphisms of the glucocorticoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33209c6bfc16a04db5cbc4528e5dc68
https://doi.org/10.1038/ki.2013.531

Bilateral Multifocal Retinal Pigment Epithelium Detachments Associated with Systemic Corticosteroids

Autor: Efstratios Mendrinos, Constantin J. Pournaras, Nikolaos Mavrakanas, Nathalie P. Dang-Burgener

Publikováno v: European Journal of Ophthalmology, Vol. 18, No 4 (2008) pp. 649-651

PURPOSE: To report an unusual case of central serous chorioretinopathy (CSC), presenting as bilateral and multifocal isolated serous retinal pigment epithelium detachments (RPEDs) following corticosteroid treatment. METHODS: An otherwise healthy 39-y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80017e0548b513444c6202ee13495f03
https://doi.org/10.1177/112067210801800428