Zobrazeno 1 - 10
of 503
pro vyhledávání: '"Prediman K, Shah"'
Autor:
Morteza Naghavi, Anthony P. Reeves, Kyle Atlas, Chenyu Zhang, Thomas Atlas, Claudia I. Henschke, David F. Yankelevitz, Matthew J. Budoff, Dong Li, Sion K. Roy, Khurram Nasir, Sabee Molloi, Zahi Fayad, Michael V. McConnell, Ioannis Kakadiaris, David J. Maron, Jagat Narula, Kim Williams, Prediman K. Shah, Daniel Levy, Nathan D. Wong
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Coronary artery calcium (CAC) scans contain valuable information beyond the Agatston Score which is currently reported for predicting coronary heart disease (CHD) only. We examined whether new artificial intelligence (AI) applied to CAC scan
Externí odkaz:
https://doaj.org/article/5dcdbca0040f43b1b76088122904b1dd
Autor:
Fernando Chernomordik, Bojan Cercek, Jianchang Zhou, Xiaoning Zhao, Nicole Wai Man Lio, Kuang-Yuh Chyu, Prediman K. Shah, Paul C. Dimayuga
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundLL-37 is the only member of the cathelicidin family of antimicrobial peptides in humans and is an autoantigen in several autoimmune diseases and in acute coronary syndrome (ACS). In this report, we profiled the specific T cell response to t
Externí odkaz:
https://doaj.org/article/05b2d9f173b040cbbb3502583f721a77
Autor:
Kuang-Yuh Chyu, Xiaoning Zhao, Jianchang Zhou, Paul C. Dimayuga, Nicole W.M. Lio, Bojan Cercek, Noah T. Trac, Eun Ji Chung, Prediman K. Shah
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
Active immunization with the apolipoprotein B-100 (ApoB-100) peptide P210 reduces experimental atherosclerosis. To advance this immunization strategy to future clinical testing, we explored the possibility of delivering P210 as an antigen using nanop
Externí odkaz:
https://doaj.org/article/4202e41de15b4c3bbae14b89cc4e796c
Autor:
Fernando Chernomordik, Bojan Cercek, Wai Man Lio, Peter M. Mihailovic, Juliana Yano, Romana Herscovici, Xiaoning Zhao, Jianchang Zhou, Kuang-Yuh Chyu, Prediman K. Shah, Paul C. Dimayuga
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The human cationic anti-microbial peptide LL-37 is a T cell self-antigen in patients with psoriasis, who have increased risk of cardiovascular events. However, the role of LL-37 as a T cell self-antigen in the context of atherosclerosis remains uncle
Externí odkaz:
https://doaj.org/article/44faf2073cbf430cb195ca7982802839
Autor:
Ujjaldeep Jaggi, Mingjie Yang, Harry H Matundan, Satoshi Hirose, Prediman K Shah, Behrooz G Sharifi, Homayon Ghiasi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008971 (2020)
After HSV-1 infection, macrophages infiltrate early into the cornea, where they play an important role in HSV-1 infection. Macrophages are divided into M1 or M2 groups based on their activation. M1 macrophages are pro-inflammatory, while M2 macrophag
Externí odkaz:
https://doaj.org/article/c45410c76a094182a425b9337d97f4e9
Publikováno v:
American Journal of Preventive Cardiology, Vol 3, Iss , Pp 100086- (2020)
A causal relationship between elevated triglycerides and cardiovascular disease is controversial, as trials of triglyceride-lowering treatments have not shown significant impact on cardiovascular outcomes. However, hypertriglyceridemia is associated
Externí odkaz:
https://doaj.org/article/ab0a79a94a0441aeafd978cb9810cee3
Autor:
Wai Man Lio, Bojan Cercek, Juliana Yano, Wei Yang, Jonathan Ghermezi, Xiaoning Zhao, Jianchang Zhou, Bo Zhou, Michael R. Freeman, Kuang-Yuh Chyu, Prediman K. Shah, Paul C. Dimayuga
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A significant body of work implicates the adaptive immune response in atherosclerosis, the main underlying cause of coronary artery disease (CAD), yet specific antigens involved remain to be fully identified. The pathobiology of CAD is influenced by
Externí odkaz:
https://doaj.org/article/9a821ab2747b4c3c82fd7c4223632e38
Autor:
Kuang-Yuh Chyu, Prediman K. Shah
Publikováno v:
JACC: Case Reports. 4:1394-1398
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba47a2297772082941a60fd7395cf428
https://doi.org/10.1016/j.jaccas.2022.06.028
https://doi.org/10.1016/j.jaccas.2022.06.028
Autor:
Peter M. Mihailovic, Wai Man Lio, Juliana Yano, Jianchang Zhou, Xiaoning Zhao, Kuang-Yuh Chyu, Prediman K. Shah, Bojan Cercek, Paul C. Dimayuga
Publikováno v:
Biochemistry and Biophysics Reports, Vol 19, Iss , Pp - (2019)
Modulating inflammation by targeting IL-1β reduces recurrent athero-thrombotic cardiovascular events without lipid lowering. This presents an opportunity to explore other pathways associated with the IL-1β signaling cascade to modulate the inflamma
Externí odkaz:
https://doaj.org/article/64042e09a3294ffdade6cbdf29c5d3ac
Autor:
Prediman K. Shah, Dalgisio Lecis
Publikováno v:
F1000Research, Vol 8 (2019)
Atherosclerotic cardiovascular disease is a leading cause of death and morbidity globally. Over the past several years, arterial inflammation has been implicated in the pathophysiology of athero-thrombosis, substantially confirming what pathologist R
Externí odkaz:
https://doaj.org/article/7e5e2f62b412459f8086eeafcec3e5cf