Zobrazeno 1 - 10
of 1 487
pro vyhledávání: '"Preclinical evaluation"'
Autor:
Lorenna E.S. Lopes, Sheilla da Silva Barroso, Joanny K.M. Caldas, Paulo R. Vasconcelos, Kirley M. Canuto, Claudio Dariva, Klebson S. Santos, Patricia Severino, Juliana C. Cardoso, Eliana B. Souto, Margarete Z. Gomes
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 14, Iss 4, Pp 435-445 (2024)
Background and aim: Tradescantia spathacea (T. spathacea) is a traditional medicinal plant from Central America and its tea, obtained by infusion, has been recognized as a functional food. The aim of this work was to investigate the effects of dry te
Externí odkaz:
https://doaj.org/article/b9b2f51ee6fd4525aded7f256be58484
Publikováno v:
Bioactive Materials, Vol 31, Iss , Pp 525-548 (2024)
Organoids, miniature and simplified in vitro model systems that mimic the structure and function of organs, have attracted considerable interest due to their promising applications in disease modeling, drug screening, personalized medicine, and tissu
Externí odkaz:
https://doaj.org/article/ee7e92ab8d1143afa0e3af85c65056a3
Autor:
Xiao-Jian He, Xiao-Ling Wang, Chuan-Shen Jiang, Dong-Gui Hong, Hai-Lan Lin, Yun-Ping Zheng, Han Li, Xin-Jiang Chen, Jian-Xiao Huang, Ling-Shuang Dai, Mei-Yan Liu, Bao-Xiang Luo, Dong-Liang Li, Da-Zhou Li, Wen Wang
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Novel endoscopic techniques used in the treatment of gastric lesions with local submucosal fibrosis need preclinical evaluation and training due to safety limitations. Therefore, the purpose of our study was to establish an animal
Externí odkaz:
https://doaj.org/article/defa50b59fe4405caa3a335be8e495c7
Autor:
Denis Babkov, Natalya Eliseeva, Kristina Adzhienko, Viktoria Bagmetova, Dmitry Danilov, Cynthia B. McReynolds, Christophe Morisseau, Bruce D. Hammock, Vladimir Burmistrov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8841 (2024)
Inhibition of soluble epoxide hydrolase (sEH) is a promising therapeutic strategy for treating neuropathic pain. These inhibitors effectively reduce diabetic neuropathic pain and inflammation induced by Freund’s adjuvant which makes them a suitable
Externí odkaz:
https://doaj.org/article/063cf443125142fdb1fad3ed14a37aeb
Publikováno v:
International Journal of Nanomedicine, Vol Volume 18, Pp 4431-4444 (2023)
Jianmin Li,1,2,* Wenyi Zhang,1,2,* Shuang Liu,1,2,* Fan Yang,2 Yupeng Zhou,2 Lin Cao,1,2 Yiming Li,1,2 Yunfei Guo,1,2 Xiang Qi,1,2 Guoping Xu,1 Jing Peng,1 Yang Zhao1,2 1Department of Radiology, The Second Hospital of Tianjin Medical Univ
Externí odkaz:
https://doaj.org/article/61f8e1bb7375440da70dc4305cb06a1c
Autor:
Esmeralda Dushku, Maxim Gavriilidis, Panagiotis Mavrommatis-Parasidis, Dimitris L Kontoyiannis
Publikováno v:
Journal of Biological Research - Thessaloniki, Vol 30, Iss 0 (2023)
RNA-binding proteins (RBPs) are essential controllers of RNA metabolism, and their deregulation can cause various pathologies. Human Antigen R (HuR) is an RBP engaged in the nuclear and cytoplasmic regulation of critical RNAs involved in cellular hom
Externí odkaz:
https://doaj.org/article/666b91cac6b44e1d88604050aec0c9d7
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Akademický článek
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Autor:
Yun Liao, Qinfang Jiang, Xinqian Huo, Li Yu, Jinling Yang, Heng Zhao, Dandan Li, Xingli Xu, Guorun Jiang, Caixing Zhang, Cong Li, Yun Li, Ying Zhang, Mingxiang Shao, Baofeng Liu, Lianzhong Shen, Shengtao Fan, Qihan Li
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 1 (2023)
Hand, foot and mouth disease is a common acute viral infectious disease that poses a serious threat to the life and health of young children. With the development of an effective inactivated EV71 vaccine, CA16 has become the main pathogen causing HFM
Externí odkaz:
https://doaj.org/article/a6f535210d924b40990d760b364c68ca