Zobrazeno 1 - 10
of 737
pro vyhledávání: '"Precision Therapy"'
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 9, Pp 1208-1213 (2024)
In recent years, with rapid development of technology of regenerative medicine and tissue engineering, brain organoids, as an innovative in vitro model system, have become a hot spot in neuroscience research and drug development. Brain organoids simu
Externí odkaz:
https://doaj.org/article/134ed3b8a377454bbd3603a2902ffd7b
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The early diagnosis of liver cancer is crucial for the treatment and depends on the coordinated use of several test procedures. Early diagnosis is crucial for precision therapy in the treatment of the hepatocellular carcinoma (HCC). Therefor
Externí odkaz:
https://doaj.org/article/7848367aa4ea49399eb18076c89087d2
Homologous Recombination Repair Testing Patterns and Outcomes in mCRPC by Alteration Status and Race
Autor:
Bilen MA, Khilfeh I, Rossi C, Muser E, Morrison L, Hilts A, Diaz L, Lefebvre P, Pilon D, George DJ
Publikováno v:
ClinicoEconomics and Outcomes Research, Vol Volume 16, Pp 657-674 (2024)
Mehmet Asim Bilen,1 Ibrahim Khilfeh,2 Carmine Rossi,3 Erik Muser,2 Laura Morrison,3 Annalise Hilts,3 Lilian Diaz,3 Patrick Lefebvre,3 Dominic Pilon,3 Daniel J George4 1Department of Hematology and Medical Oncology, Emory University School of Medicine
Externí odkaz:
https://doaj.org/article/21b1cbb5bb98427383e18c20de7c5a9f
Autor:
Xinxin Zhang, Tingting Wang, Xiangqing Fan, Tianze Zhang, Rui Qiu, Yuqi Wu, Meixia Wang, Yizhi Zhang, Meng Li, Na Cai, Ying Guan, Hong-Hui Wang
Publikováno v:
Exploration of Immunology, Vol 4, Iss 4, Pp 533-553 (2024)
Diabetic wound healing presents a unique and complex challenge due to the impaired cellular and molecular functions associated with diabetes. Chronic wounds in diabetic patients are characterized by prolonged inflammation, reduced angiogenesis, and i
Externí odkaz:
https://doaj.org/article/c3f1946969584aa99b51be3fc63860a1
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 783-91 (2024)
Hepatocellular carcinoma (HCC) is among the most common malignant liver tumors. Despite progress in anticancer drugs and surgical approaches, early detection of HCC remains challenging, often leading to late-stage diagnosis where rapid disease progre
Externí odkaz:
https://doaj.org/article/830c8f01066a400da834d0681c7b0fa5
Autor:
Asif Shahzad, Zhuoran Teng, Muhammad Yameen, Wenjing Liu, Kun Cui, Xiangjie Liu, Yijian Sun, Qiuxin Duan, JiaoJiao Xia, Yurong Dong, Ziyuan Bai, Dongmei Peng, Jinshan Zhang, Zhe Xu, Jiang Pi, Zhe Yang, Qiao Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117465- (2024)
The kidney plays a crucial role in regulating homeostasis within the human body. Renal cell carcinoma (RCC) is the most common form of kidney cancer, accounting for nearly 90 % of all renal malignancies. Despite the availability of various therapeuti
Externí odkaz:
https://doaj.org/article/c4604f5b4b9548ae8d25c75387dfb66f
Autor:
Qinyu Li, Yanan Wang, Junjie Chen, Kai Zeng, Chengwei Wang, Xiangdong Guo, Zhiquan Hu, Jia Hu, Bo Liu, Jun Xiao, Peng Zhou
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37256- (2024)
Background: It has been demonstrated that aberrant androgen receptor (AR) signaling contributes to the pathogenesis of prostate cancer (PCa). To date, the most efficacious strategy for the treatment of PCa remains to target the AR signaling axis. How
Externí odkaz:
https://doaj.org/article/36e3ef398385471db03e7c901a548913
Publikováno v:
Waike lilun yu shijian, Vol 29, Iss 02, Pp 114-120 (2024)
Biliary tract carcinoma exhibits high heterogeneity at the genomic, epigenetic, and molecular expression levels. The patients even with the same pathological morphology and clinical stage of biliary tract malignant tumors have substantial differences
Externí odkaz:
https://doaj.org/article/48e4ac98dbea4b509250b3a25f406621
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35112- (2024)
Background: We assessed the response to sulfonylureas and the functional characteristics of HNF1A mutations in patients with maturity-onset diabetes of the young type 3 (MODY3). Methods: We recruited a family with suspected MODY in this study, and ge
Externí odkaz:
https://doaj.org/article/97c837c96c4f4c959a6592f9b4d45558
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117106- (2024)
Coupled drugs, especially antibody-coupled drugs (ADCs), are a hot topic in oncology. As the development of ADCs has progressed, different coupling modes have emerged, inspired by their structural design have emerged. Technological advances have led
Externí odkaz:
https://doaj.org/article/7e6ecbdbe15643e2afe9b4097097b006