Zobrazeno 1 - 10
of 753
pro vyhledávání: '"Preben Bo, Mortensen"'
Autor:
Filip Ottosson, Francesco Russo, Anna Abrahamsson, Nadia MacSween, Julie Courraud, Kristin Skogstrand, Olle Melander, Ulrika Ericson, Marju Orho-Melander, Arieh S. Cohen, Jakob Grove, Preben Bo Mortensen, David M. Hougaard, Madeleine Ernst
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background The prevalence of autism in Denmark has been increasing, reaching 1.65% among 10-year-old children, and similar trends are seen elsewhere. Although there are several factors associated with autism, including genetic, environmental
Externí odkaz:
https://doaj.org/article/c2ef8d3921514b3ea5ecafec64670785
Autor:
Trine Munk-Olsen, Arianna Di Florio, Kathrine B. Madsen, Clara Albiñana, Merete L. Mægbæk, Veerle Bergink, Vibe G. Frøkjær, Esben Agerbo, Bjarni J. Vilhjálmsson, Thomas Werge, Merete Nordentoft, David M. Hougaard, Anders D. Børglum, Ole Mors, Preben Bo Mortensen, Xiaoqin Liu
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract It remains inconclusive whether postpartum depression (PPD) and depression with onset outside the postpartum period (MDD) are genetically distinct disorders. We aimed to investigate whether polygenic risk scores (PGSs) for major mental disor
Externí odkaz:
https://doaj.org/article/55dd8d9090d14f2ea460f664133aba97
Autor:
Clara Albiñana, Zhihong Zhu, Andrew J. Schork, Andrés Ingason, Hugues Aschard, Isabell Brikell, Cynthia M. Bulik, Liselotte V. Petersen, Esben Agerbo, Jakob Grove, Merete Nordentoft, David M. Hougaard, Thomas Werge, Anders D. Børglum, Preben Bo Mortensen, John J. McGrath, Benjamin M. Neale, Florian Privé, Bjarni J. Vilhjálmsson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The predictive performance of polygenic scores (PGS) is largely dependent on the number of samples available to train the PGS. Increasing the sample size for a specific phenotype is expensive and takes time, but this sample size can be effec
Externí odkaz:
https://doaj.org/article/65c6fd7da745423fbb7f56199da61c83
Autor:
Clara Albiñana, Zhihong Zhu, Nis Borbye-Lorenzen, Sanne Grundvad Boelt, Arieh S. Cohen, Kristin Skogstrand, Naomi R. Wray, Joana A. Revez, Florian Privé, Liselotte V. Petersen, Cynthia M. Bulik, Oleguer Plana-Ripoll, Katherine L. Musliner, Esben Agerbo, Anders D. Børglum, David M. Hougaard, Merete Nordentoft, Thomas Werge, Preben Bo Mortensen, Bjarni J. Vilhjálmsson, John J. McGrath
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The vitamin D binding protein (DBP), encoded by the group-specific component (GC) gene, is a component of the vitamin D system. In a genome-wide association study of DBP concentration in 65,589 neonates we identify 26 independent loci, 17 of
Externí odkaz:
https://doaj.org/article/15845a4d45ac43fd9c945f9f49a9c9cc
Autor:
Clara Albiñana, Zhihong Zhu, Nis Borbye-Lorenzen, Sanne Grundvad Boelt, Arieh S. Cohen, Kristin Skogstrand, Naomi R. Wray, Joana A. Revez, Florian Privé, Liselotte V. Petersen, Cynthia M. Bulik, Oleguer Plana-Ripoll, Katherine L. Musliner, Esben Agerbo, Anders D. Børglum, David M. Hougaard, Merete Nordentoft, Thomas Werge, Preben Bo Mortensen, Bjarni J. Vilhjálmsson, John J. McGrath
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9a04756801ae4be7b59d11f637177242
Autor:
Veera M. Rajagopal, Andrea Ganna, Jonathan R. I. Coleman, Andrea Allegrini, Georgios Voloudakis, Jakob Grove, Thomas D. Als, Henriette T. Horsdal, Liselotte Petersen, Vivek Appadurai, Andrew Schork, Alfonso Buil, Cynthia M. Bulik, Jonas Bybjerg-Grauholm, Marie Bækvad-Hansen, David M. Hougaard, Ole Mors, Merete Nordentoft, Thomas Werge, iPSYCH-Broad Consortium, Preben Bo Mortensen, Gerome Breen, Panos Roussos, Robert Plomin, Esben Agerbo, Anders D. Børglum, Ditte Demontis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Cognitive functions of individuals with psychiatric disorders differ from that of the general population. Such cognitive differences often manifest early in life as differential school performance and have a strong genetic basis. Here we mea
Externí odkaz:
https://doaj.org/article/ed05f0cb3a754525a813a4518791dddd
Autor:
Oliver Pain, Karen Hodgson, Vassily Trubetskoy, Stephan Ripke, Victoria S. Marshe, Mark J. Adams, Enda M. Byrne, Adrian I. Campos, Tania Carrillo-Roa, Annamaria Cattaneo, Thomas D. Als, Daniel Souery, Mojca Z. Dernovsek, Chiara Fabbri, Caroline Hayward, Neven Henigsberg, Joanna Hauser, James L. Kennedy, Eric J. Lenze, Glyn Lewis, Daniel J. Müller, Nicholas G. Martin, Benoit H. Mulsant, Ole Mors, Nader Perroud, David J. Porteous, Miguel E. Rentería, Charles F. Reynolds, III, Marcella Rietschel, Rudolf Uher, Eleanor M. Wigmore, Wolfgang Maier, Naomi R. Wray, Katherine J. Aitchison, Volker Arolt, Bernhard T. Baune, Joanna M. Biernacka, Guido Bondolfi, Katharina Domschke, Masaki Kato, Qingqin S. Li, Yu-Li Liu, Alessandro Serretti, Shih-Jen Tsai, Gustavo Turecki, Richard Weinshilboum, Andrew M. McIntosh, Cathryn M. Lewis, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Manuel Mattheisen, Maciej Trzaskowski, Abdel Abdellaoui, Esben Agerbo, Tracy M. Air, Till F.M. Andlauer, Silviu-Alin Bacanu, Marie Bækvad-Hansen, Aartjan T.F. Beekman, Tim B. Bigdeli, Elisabeth B. Binder, Julien Bryois, Henriette N. Buttenschøn, Jonas Bybjerg-Grauholm, Na Cai, Enrique Castelao, Jane Hvarregaard Christensen, Toni-Kim Clarke, Jonathan R.I. Coleman, Lucía Colodro-Conde, Baptiste Couvy-Duchesne, Nick Craddock, Gregory E. Crawford, Gail Davies, Ian J. Deary, Franziska Degenhardt, Eske M. Derks, Nese Direk, Conor V. Dolan, Erin C. Dunn, Thalia C. Eley, Valentina Escott-Price, Farnush Farhadi Hassan Kiadeh, Hilary K. Finucane, Jerome C. Foo, Andreas J. Forstner, Josef Frank, Héléna A. Gaspar, Michael Gill, Fernando S. Goes, Scott D. Gordon, Jakob Grove, Lynsey S. Hall, Christine Søholm Hansen, Thomas F. Hansen, Stefan Herms, Ian B. Hickie, Per Hoffmann, Georg Homuth, Carsten Horn, Jouke-Jan Hottenga, David M. Hougaard, David M. Howard, Marcus Ising, Rick Jansen, Ian Jones, Lisa A. Jones, Eric Jorgenson, James A. Knowles, Isaac S. Kohane, Julia Kraft, Warren W. Kretzschmar, Zoltán Kutalik, Yihan Li, Penelope A. Lind, Donald J. MacIntyre, Dean F. MacKinnon, Robert M. Maier, Jonathan Marchini, Hamdi Mbarek, Patrick McGrath, Peter McGuffin, Sarah E. Medland, Divya Mehta, Christel M. Middeldorp, Evelin Mihailov, Yuri Milaneschi, Lili Milani, Francis M. Mondimore, Grant W. Montgomery, Sara Mostafavi, Niamh Mullins, Matthias Nauck, Bernard Ng, Michel G. Nivard, Dale R. Nyholt, Paul F. O’Reilly, Hogni Oskarsson, Michael J. Owen, Jodie N. Painter, Carsten Bøcker Pedersen, Marianne Giørtz Pedersen, Roseann E. Peterson, Wouter J. Peyrot, Giorgio Pistis, Danielle Posthuma, Jorge A. Quiroz, Per Qvist, John P. Rice, Brien P. Riley, Margarita Rivera, Saira Saeed Mirza, Robert Schoevers, Eva C. Schulte, Ling Shen, Jianxin Shi, Stanley I. Shyn, Engilbert Sigurdsson, Grant C.B. Sinnamon, Johannes H. Smit, Daniel J. Smith, Hreinn Stefansson, Stacy Steinberg, Fabian Streit, Jana Strohmaier, Katherine E. Tansey, Henning Teismann, Alexander Teumer, Wesley Thompson, Pippa A. Thomson, Thorgeir E. Thorgeirsson, Matthew Traylor, Jens Treutlein, André G. Uitterlinden, Daniel Umbricht, Sandra Van der Auwera, Albert M. van Hemert, Alexander Viktorin, Peter M. Visscher, Yunpeng Wang, Bradley T. Webb, Shantel Marie Weinsheimer, Jürgen Wellmann, Gonneke Willemsen, Stephanie H. Witt, Yang Wu, Hualin S. Xi, Jian Yang, Futao Zhang, Klaus Berger, Dorret I. Boomsma, Sven Cichon, Udo Dannlowski, E.J.C. de Geus, J. Raymond DePaulo, Enrico Domenici, Tõnu Esko, Hans J. Grabe, Steven P. Hamilton, Andrew C. Heath, Kenneth S. Kendler, Stefan Kloiber, Susanne Lucae, Pamela A.F. Madden, Patrik K. Magnusson, Andres Metspalu, Preben Bo Mortensen, Bertram Müller-Myhsok, Merete Nordentoft, Markus M. Nöthen, Michael C. O’Donovan, Sara A. Paciga, Nancy L. Pedersen, Brenda W.J.H. Penninx, Roy H. Perlis, James B. Potash, Martin Preisig, Catherine Schaefer, Thomas G. Schulze, Jordan W. Smoller, Kari Stefansson, Henning Tiemeier, Henry Völzke, Myrna M. Weissman, Thomas Werge, Douglas F. Levinson, Gerome Breen, Anders D. Børglum, Patrick F. Sullivan
Publikováno v:
Biological Psychiatry Global Open Science, Vol 2, Iss 2, Pp 115-126 (2022)
Background: Antidepressants are a first-line treatment for depression. However, only a third of individuals experience remission after the first treatment. Common genetic variation, in part, likely regulates antidepressant response, yet the success o
Externí odkaz:
https://doaj.org/article/c97a14decdf44013b3e7f514e212f02f
Autor:
Morten Dybdahl Krebs, Gonçalo Espregueira Themudo, Michael Eriksen Benros, Ole Mors, Anders D. Børglum, David Hougaard, Preben Bo Mortensen, Merete Nordentoft, Michael J. Gandal, Chun Chieh Fan, Daniel H. Geschwind, Andrew J. Schork, Thomas Werge, Wesley K. Thompson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Schizophrenia is a complex disorder where individuals experience different symptoms and outcomes that can be captured by patterns in other diagnoses. Here the authors use computational approaches to summarize these patterns and suggest they are assoc
Externí odkaz:
https://doaj.org/article/219901d0dd4a433c9949807e8340f338
Autor:
Nanna Weye, Natalie C. Momen, Harvey A. Whiteford, Maria Klitgaard Christensen, Kim Moesgaard Iburg, Damian F. Santomauro, Esben Agerbo, Preben Bo Mortensen, Carsten Bøcker Pedersen, John J. McGrath, Oleguer Plana-Ripoll
Publikováno v:
BJPsych Open, Vol 8 (2022)
Background General medical conditions (GMCs) often co-occur with mental and substance use disorders (MSDs). Aims To explore the contribution of GMCs to the burden of disease in people with MSDs, and investigate how this varied by age. Method A popu
Externí odkaz:
https://doaj.org/article/27c12e285caa48f2beee9cc78352f2ab
Autor:
Linda Ejlskov, Jesper N. Wulff, Amy Kalkbrenner, Christine Ladd-Acosta, M. Danielle Fallin, Esben Agerbo, Preben Bo Mortensen, Brian K. Lee, Diana Schendel
Publikováno v:
Biological Psychiatry Global Open Science, Vol 1, Iss 2, Pp 156-164 (2021)
Background: A family history of specific disorders (e.g., autism, depression, epilepsy) has been linked to risk for autism spectrum disorder (ASD). This study examines whether family history data could be used for ASD risk prediction. Methods: We fol
Externí odkaz:
https://doaj.org/article/e51e38f4826f496888cb3dc8e779a73c