Zobrazeno 1 - 10
of 86
pro vyhledávání: '"PreQ1 riboswitch"'
Autor:
Liberman, Joseph A., Suddala, Krishna C., Aytenfisu, Asaminew, Chan, Dalen, Belashov, Ivan A., Salim, Mohammad, Mathews, David H., Spitale, Robert C., Walter, Nils G., Wedekind, Joseph E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Jul 01. 112(27), E3485-E3494.
Externí odkaz:
https://www.jstor.org/stable/26463743
Publikováno v:
Journal of the American Chemical Society. 143:7968-7978
Riboswitches are regulatory elements of bacterial mRNA which function with conformational switching upon binding of specific cellular metabolites. In particular, transcriptional riboswitches regulate gene expression kinetically through the conformati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3606600a598e33c102402e19850052e
https://doi.org/10.1021/jacs.1c01077
https://doi.org/10.1021/jacs.1c01077
Publikováno v:
Journal of Molecular Biology. 432:4523-4543
Single-stranded noncoding regulatory RNAs, as exemplified by bacterial riboswitches, are highly dynamic. The conformational dynamics allow the riboswitch to reach maximum switching efficiency under appropriate conditions. Here we characterize the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4002ee2f7b91239c92e94e57df39544
https://doi.org/10.1016/j.jmb.2020.06.002
https://doi.org/10.1016/j.jmb.2020.06.002
Autor:
Debapratim Dutta, Joseph E. Wedekind
Publikováno v:
Journal of Biological Chemistry. 295:2555-2567
Riboswitches are a class of nonprotein-coding RNAs that directly sense cellular metabolites to regulate gene expression. They are model systems for analyzing RNA-ligand interactions and are established targets for antibacterial agents. Many studies h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::349ba2f2c145b47e7ddc5d641b965e62
https://doi.org/10.1074/jbc.ra119.010755
https://doi.org/10.1074/jbc.ra119.010755
Autor:
Sumirtha Balaratnam, Curran Rhodes, Tomoyuki Numata, Kamyar Yazdani, John S. Schneekloth, Desta Doro Bume, James A. Kelley, Christopher C. Lai, Danny Incarnato, Colleen M. Connelly, Philip John Homan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, 12(1):5856. Nature Publishing Group
Nature Communications, 12(1):5856. Nature Publishing Group
The role of metabolite-responsive riboswitches in regulating gene expression in bacteria is well known and makes them useful systems for the study of RNA-small molecule interactions. Here, we study the PreQ1 riboswitch system, assessing sixteen diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb41f6557973cd76e792410c6666f9bc
https://hdl.handle.net/11370/13ba1956-846b-4846-a2d7-a0e584340c7e
https://hdl.handle.net/11370/13ba1956-846b-4846-a2d7-a0e584340c7e
Autor:
Bishwajit Ganguly, Tusar Bandyopadhyay, Shibaji Ghosh, Kalyanashis Jana, Padmaja D. Wakchaure
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 38:4635-4643
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2b6c90c31149324b3bd16ae991367ac
https://doi.org/10.1080/07391102.2019.1682675
https://doi.org/10.1080/07391102.2019.1682675
Autor:
Ranu S. Sinniah, Adrian R. Ferré-D'Amaré, Joseph J. Barchi, Michelle H. Moon, Colleen M. Connelly, Robert E. Boer, John S. Schneekloth, Tomoyuki Numata
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Riboswitches are naturally occurring RNA aptamers that regulate gene expression by binding to specific small molecules. Riboswitches control the expression of essential bacterial genes and are important models for RNA-small molecule recognition. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ac141f7122e2c41b118709718d9083
https://doaj.org/article/8034f2bb7b9a4f67ba723ce0a274264d
https://doaj.org/article/8034f2bb7b9a4f67ba723ce0a274264d
Riboswitches are gene-regulating mRNA segments most commonly found in bacteria. A riboswitch contains an aptamer domain that binds to a ligand, causing a conformational change in a downstream expression platform. The aptamer domain of the Class I pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf901728b526f2c07a49c04a41dd934f
https://doi.org/10.1101/2021.07.22.453416
https://doi.org/10.1101/2021.07.22.453416
Autor:
Guodong Hu, Huan-Xiang Zhou
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 11, p e1009603 (2021)
PLoS Computational Biology, Vol 17, Iss 11, p e1009603 (2021)
Riboswitches are naturally occurring RNA elements that control bacterial gene expression by binding to specific small molecules. They serve as important models for RNA-small molecule recognition and have also become a novel class of targets for devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b0069379645264080453c780b924e8
https://doi.org/10.1101/2021.07.13.452201
https://doi.org/10.1101/2021.07.13.452201
Publikováno v:
Biochemistry. 57:2923-2931
Site-directed spin labeling is a powerful tool for investigating the conformation and dynamics of biomacromolecules such as RNA. Here we introduce a spin labeling strategy based on click chemistry in solution that, in combination with enzymatic ligat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7c832ac95a3ff2374b60abae1da9f5
https://doi.org/10.1021/acs.biochem.8b00040
https://doi.org/10.1021/acs.biochem.8b00040