Antibody repertoire development in fetal and neonatal piglets. XII. Three IGLV genes comprise 70% of the pre-immune repertoire and there is little junctional diversity

Autor: Wertz, Nancy, Vazquez, Jonathon, Wells, Kevin, Sun, Jishan, Butler, John E.

Publikováno v: In Molecular Immunology October 2013 55(3-4):319-328

Antibody repertoire development in fetal and neonatal piglets. XII. Three IGLV genes comprise 70% of the pre-immune repertoire and there is little junctional diversity

Autor: Kevin D. Wells, Jonathon Vazquez, Jishan Sun, John E. Butler, Nancy Wertz

Publikováno v: Molecular Immunology. 55:319-328

We characterized 239 lambda rearrangements from fetal and germfree (GF) piglets to: (1) determine if transcripts recovered from the earliest sites of B cell lymphogenesis were unique (2) determine what proportion of the genome is used to form the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a618c8893abfd9cba31c24bf388312
https://doi.org/10.1016/j.molimm.2013.03.012

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients

Autor: Cécile Alanio, Francesco Nicoli, Philippe Sultanik, Tobias Flecken, Brieuc Perot, Darragh Duffy, Elisabetta Bianchi, Annick Lim, Emmanuel Clave, Marit M van Buuren, Aurélie Schnuriger, Kerstin Johnsson, Jeremy Boussier, Antoine Garbarg-Chenon, Laurence Bousquet, Estelle Mottez, Ton N Schumacher, Antoine Toubert, Victor Appay, Farhad Heshmati, Robert Thimme, Stanislas Pol, Vincent Mallet, Matthew L Albert

Publikováno v: eLife, Vol 4 (2015)

Chronic infection perturbs immune homeostasis. While prior studies have reported dysregulation of effector and memory cells, little is known about the effects on naïve T cell populations. We performed a cross-sectional study of chronic hepatitis C (

Externí odkaz: https://doaj.org/article/d89d3f83b9d7475b9d4f81ba46b5ec3d

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Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients

Autor: Tobias Flecken, Jeremy Boussier, Farhad Heshmati, Vincent Mallet, Marit M. van Buuren, Francesco Nicoli, Matthew L. Albert, Aurélie Schnuriger, Ton N. Schumacher, Philippe Sultanik, Laurence Bousquet, Elisabetta Bianchi, Robert Thimme, Annick Lim, A. Garbarg-Chenon, Darragh Duffy, Antoine Toubert, Kerstin Johnsson, Emmanuel Clave, Stanislas Pol, Estelle Mottez, Cécile Alanio, Brieuc Perot, Victor Appay

Publikováno v: eLife
eLife, eLife Sciences Publication, 2015, 4, pp.e07916. ⟨10.7554/eLife.07916⟩
eLife, 2015, 4, pp.e07916. ⟨10.7554/eLife.07916⟩
eLife, eLife Sciences Publication, 2015, 4, pp.e07916. 〈10.7554/eLife.07916〉
eLife, Vol 4 (2015)

Chronic infection perturbs immune homeostasis. While prior studies have reported dysregulation of effector and memory cells, little is known about the effects on naïve T cell populations. We performed a cross-sectional study of chronic hepatitis C (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06b2865cf6d3237f33d84a47e5edb6c
https://hal.sorbonne-universite.fr/hal-01306801/document