Zobrazeno 1 - 10
of 277
pro vyhledávání: '"Pre-Clinical Research Report"'
Publikováno v:
Journal of International Medical Research, Vol 50 (2022)
The Journal of International Medical Research
The Journal of International Medical Research
Objective To identify key genes in hepatitis C virus (HCV)-induced cirrhosis and to predict effective drugs for its treatment. Methods Three datasets were used to screen for differentially expressed genes (DEGs) and differentially methylated genes (D
Publikováno v:
Journal of International Medical Research, Vol 50 (2022)
The Journal of International Medical Research
The Journal of International Medical Research
Objective To investigate the tumorigenic role of spen paralogue and orthologue C-terminal domain-containing 1 (SPOCD1) in hepatocellular carcinoma (HCC) and identify the upstream regulatory mechanism. Methods We analyzed SPOCD1 and miR-133-3p express
Publikováno v:
The Journal of International Medical Research
Journal of International Medical Research, Vol 49 (2021)
Journal of International Medical Research, Vol 49 (2021)
Objective To evaluate the antiviral activity of the oral disinfectant povidone-iodine (PVP-I) against severe acute respiratory syndrome-coronavirus-2 (SARS-CoV2) in vitro . Methods The cytotoxic effects of PVP-I were determined in Vero and Calu-3 cel
Autor:
Azar Dokht Khosravi, Mehrandokht Sirous, Morteza Saki, Sakineh Seyed-Mohammadi, Seyed Reza Modares Mousavi, Hojat Veisi, Asma Abbasinezhad Poor
Publikováno v:
The Journal of International Medical Research
Objective To investigate correlations between ABO/rhesus (Rh) blood group antigens and anti- Helicobacter pylori and anti-cytotoxin-associated gene A (CagA) seropositivity in blood donors. Methods A total of 311 blood donors were enrolled. ABO and Rh
Publikováno v:
The Journal of International Medical Research
Journal of International Medical Research, Vol 49 (2021)
Journal of International Medical Research, Vol 49 (2021)
Objective To quantitate plasma interleukin-6 (IL-6) levels in healthy individuals and to clarify how these levels are affected by blood sample handling procedures during short-term storage. Methods Ethylenediaminetetraacetic acid (EDTA)-treated plasm
Autor:
Xing, Wang, Shuchun, Chen, Dan, Lv, Zelin, Li, Luping, Ren, Haijiao, Zhu, Xing, Xie, Yang, Liu
Publikováno v:
The Journal of International Medical Research
Objective To investigate the effect of liraglutide on the browning of white fat and the suppression of obesity via regulating microRNA (miR)-27b in vivo and in vitro. Methods Sprague-Dawley rats were fed a high-fat (HF) diet and 3T3-L1 pre-adipocytes
Publikováno v:
The Journal of International Medical Research
Objective To investigate Krüppel-like factor 17 (KLF17) expression in normal and gastric cancer tissues and cell lines. Methods Levels of KLF17 mRNA and protein in GES-1 normal gastric mucosal cells, and NCI-N87, SGC-7901, BGC-823 and HGC-27 gastric
Publikováno v:
The Journal of International Medical Research
Journal of International Medical Research, Vol 49 (2021)
Journal of International Medical Research, Vol 49 (2021)
Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women of reproductive age. Chemerin has recently been discovered as a novel adipokine associated with obesity and metabolic syndrome. Excessive autophagy activity and ove
Publikováno v:
Journal of International Medical Research, Vol 49 (2021)
The Journal of International Medical Research
The Journal of International Medical Research
Objective To explore whether dihydroartemisinin (DHA) can block interleukin (IL)-6-induced epithelial–mesenchymal transition (EMT) in laryngeal squamous cell carcinoma (LSCC). Methods The expression of SLUG, signal transducer and activator of trans
Publikováno v:
The Journal of International Medical Research
Journal of International Medical Research, Vol 49 (2021)
Journal of International Medical Research, Vol 49 (2021)
Objective To investigate the prognostic value of the co-chaperone protein DnaJ Heat Shock Protein Family (Hsp40) Member B11 (DNAJB11) in thyroid carcinoma (THCA). Methods This bioinformatics analysis study evaluated the prognostic value of DNAJB11 mR