Zobrazeno 1 - 10
of 716
pro vyhledávání: '"Prdm9"'
Autor:
Yi Qiu, Yoon Mo Kang, Christopher Korfmann, Fanny Pouyet, Andrew Eckford, Alexander F. Palazzo
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background In vertebrates, most protein-coding genes have a peak of GC-content near their 5′ transcriptional start site (TSS). This feature promotes both the efficient nuclear export and translation of mRNAs. Despite the importance of GC-c
Externí odkaz:
https://doaj.org/article/4d6e819d1914485eb98112d2551117af
Akademický článek
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Autor:
Paris Ladias, Georgios S. Markopoulos, Charilaos Kostoulas, Ioanna Bouba, Agis Georgiou, Sofia Markoula, Ioannis Georgiou
Publikováno v:
BioMedInformatics, Vol 3, Iss 2, Pp 267-279 (2023)
Holliday junctions are the first recognized templates of legitimate recombination. Their prime physiological role is meiotic homologous recombination, resulting in rearrangements of the genetic material. In humans, recombination hotspots follow a dis
Externí odkaz:
https://doaj.org/article/173aa6aa11b24cd1b82c8199e1d964e4
Publikováno v:
Animals, Vol 14, Iss 9, p 1345 (2024)
Meiotic recombination is a prevalent process in eukaryotic sexual reproduction organisms that plays key roles in genetic diversity, breed selection, and species evolution. However, the recombination events differ across breeds and even within breeds.
Externí odkaz:
https://doaj.org/article/ef59f35c95fb419f999e5d4a8aa9c015
Down the Penrose stairs, or how selection for fewer recombination hotspots maintains their existence
Publikováno v:
eLife, Vol 12 (2023)
In many species, meiotic recombination events tend to occur in narrow intervals of the genome, known as hotspots. In humans and mice, double strand break (DSB) hotspot locations are determined by the DNA-binding specificity of the zinc finger array o
Externí odkaz:
https://doaj.org/article/c285cf48dbce43f3a2da569a3206e833
Autor:
Jianchun Zhang, Jie Kong, Jiawang Cao, Ping Dai, Baolong Chen, Jian Tan, Xianhong Meng, Kun Luo, Qiang Fu, Peiming Wei, Sheng Luan, Juan Sui
Publikováno v:
Biology, Vol 13, Iss 4, p 218 (2024)
The Pacific whiteleg shrimp (Penaeus vannamei) is a highly significant species in shrimp aquaculture. In the production of shrimp larvae, noticeable variations in the reproductive capacity among female individuals have been observed. Some females exp
Externí odkaz:
https://doaj.org/article/b3f573cdbe0643e28268f776bbf319b8
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background PRDM9 is a key regulator of meiotic recombination in most metazoans, responsible for reshuffling parental genomes. During meiosis, the PRDM9 protein recognizes and binds specific target motifs via its array of C2H2 zinc-fingers en
Externí odkaz:
https://doaj.org/article/524804e8e99f431f904ed760f6bd6f10
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
SONIKA AHLAWAT, REKHA SHARMA, REENA ARORA, HIMANI SHARMA, RENUKA SEHRAWAT, ANNU SHARMA, KARAN VEER SINGH, RAMESH KUMAR VIJH
Publikováno v:
Indian Journal of Animal Sciences, Vol 92, Iss 12 (2022)
Recombination regulator, PRDM9, has been regarded as the most rapidly evolving gene in the genomes of many metazoans, in addition to being acknowledged as the sole speciation gene in vertebrates. It has become the focus of many scientific investigati
Externí odkaz:
https://doaj.org/article/ef8123a102144594ba34ad2cde41bf97
Autor:
Ondrej Mihola, Vladimir Landa, Florencia Pratto, Kevin Brick, Tatyana Kobets, Fitore Kusari, Srdjan Gasic, Fatima Smagulova, Corinne Grey, Petr Flachs, Vaclav Gergelits, Karel Tresnak, Jan Silhavy, Petr Mlejnek, R. Daniel Camerini-Otero, Michal Pravenec, Galina V. Petukhova, Zdenek Trachtulec
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-20 (2021)
Abstract Background Vertebrate meiotic recombination events are concentrated in regions (hotspots) that display open chromatin marks, such as trimethylation of lysines 4 and 36 of histone 3 (H3K4me3 and H3K36me3). Mouse and human PRDM9 proteins catal
Externí odkaz:
https://doaj.org/article/03a0d82fd99840bf996152ad7bf19c03