Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Praxedis Martin"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Interleukin (IL)-1 family cytokines initiate inflammatory responses, and shape innate and adaptive immunity. They play important roles in host defense, but excessive immune activation can also lead to the development of chronic inflammatory diseases.
Externí odkaz:
https://doaj.org/article/6c907043bc8f404bb183c0b05c09fdd8
Autor:
Marianne Böni-Schnetzler, Stéphanie P. Häuselmann, Elise Dalmas, Daniel T. Meier, Constanze Thienel, Shuyang Traub, Friederike Schulze, Laura Steiger, Erez Dror, Praxedis Martin, Pedro L. Herrera, Cem Gabay, Marc Y. Donath
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1774-1786 (2018)
Summary: Interleukin-1 receptor antagonist (IL-1Ra) is elevated in the circulation during obesity and type 2 diabetes (T2D) but is decreased in islets from patients with T2D. The protective role of local IL-1Ra was investigated in pancreatic islet β
Externí odkaz:
https://doaj.org/article/57e70e42c68f4540a15c19f5916584e6
Autor:
Laura Comas, Christopher J. Froelich, Praxedis Martin, Cheikh Menaa, Markus M. Simon, Llipsy Santiago, Eva M. Galvez, Stuart M. Sprague, Luis Martínez-Lostao, Sunil S. Metkar, Cem Gabay, Paula Jaime-Sánchez, Erica Esser, Nadina Erill, Sri Raja, Maykel Arias, Julián Pardo, Victor Gonzalez-Rumayor
Publikováno v:
Arthritis & Rheumatology. 69:320-334
Objective Granzyme A (GzmA) levels are elevated in the plasma and synovium of patients with rheumatoid arthritis (RA), suggesting involvement of this protease in the pathogenesis of the disease. GzmA contributes to sepsis by regulating the production
Autor:
Gaby Palmer, Praxedis Martin, Sylvain Lemeille, Jérémie David Goldstein, Cem Gabay, Emiliana Rodriguez, Jennifer Palomo
Publikováno v:
Journal of Immunology, Vol. 204, No 4 (2020) pp. 967-979
The inflammatory effects of IL-1α/β are controlled by IL-1R antagonist (IL-1Ra). One IL-1Ra isoform is secreted, whereas three other isoforms (intracellular IL-1Ra [icIL-1Ra] 1, 2, and 3) are supposed to remain intracellular because of the absence
Publikováno v:
Abstracts.
Career situation of first and presenting author Post-doctoral fellow. Introduction The inflammatory effects of interleukin (IL)-1 are tightly controlled by IL-1 receptor antagonist (IL-1Ra), which blocks the binding of both IL-1α and IL-1β to IL-1R
Autor:
Cem Gabay, Praxedis Martin, Jennifer Palomo, Sabina Troccaz, Gaby Palmer, Charlotte Girard-Guyonvarc'h, Emiliana Rodriguez
Publikováno v:
Oral presentations.
Introduction Macrophage activation syndrome (MAS) is a severe condition, which can appear as a complication of inflammatory rheumatic diseases such as systemic juvenile idiopathic arthritis (sJIA) and adult onset Still’s disease (AOSD), a viral inf
Autor:
Praxedis Martin, Laura Steiger, Constanze Thienel, Cem Gabay, Daniel T. Meier, Stéphanie P. Häuselmann, Shuyang Traub, Pedro Luis Herrera, Marianne Böni-Schnetzler, Marc Y. Donath, Erez Dror, Friederike Schulze, Elise Dalmas
Publikováno v:
Cell Reports, Vol. 22, No 7 (2018) pp. 1774-1786
Cell Reports, Vol 22, Iss 7, Pp 1774-1786 (2018)
Cell Reports, Vol 22, Iss 7, Pp 1774-1786 (2018)
Summary: Interleukin-1 receptor antagonist (IL-1Ra) is elevated in the circulation during obesity and type 2 diabetes (T2D) but is decreased in islets from patients with T2D. The protective role of local IL-1Ra was investigated in pancreatic islet β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb78533f0101d8ec74899939a149c78
https://archive-ouverte.unige.ch/unige:102781
https://archive-ouverte.unige.ch/unige:102781
Autor:
Sabina Troccaz, Emiliana Rodriguez, Gaby Palmer, Charlotte Girard-Guyonvarc'h, Praxedis Martin, Jennifer Palomo, Cem Gabay
Publikováno v:
Blood, Vol. 131, No 13 (2018) pp. 1430-1441
The term macrophage activation syndrome (MAS) defines a severe, potentially fatal disorder characterized by overwhelming inflammation and multiorgan involvement. Interleukin-18 (IL-18) is a proinflammatory cytokine belonging to the IL-1 family, the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f316840da55206d411037e700233f6ac
https://archive-ouverte.unige.ch/unige:110668
https://archive-ouverte.unige.ch/unige:110668
Autor:
Dominique Talabot-Ayer, Christian Alexander Seemayer, Solenne Vigne, Gaby Palmer, Christian Vesin, Praxedis Martin, Cem Gabay
Publikováno v:
Journal of immunology (Baltimore Md. : 1950)
Journal of Immunology
Journal of Immunology, Vol. 194, No 2 (2015) pp. 750-60
Journal of Immunology
Journal of Immunology, Vol. 194, No 2 (2015) pp. 750-60
IL-33 is a cytokine of the IL-1 family, which signals through the ST2 receptor. Previous studies emphasized a role for IL-33 in shaping innate and adaptive immune responses. IL-33 was also reported to modulate myelopoiesis and myeloid cell activity.
Autor:
Dominique Talabot-Ayer, Gaby Palmer, Emiliana Rodriguez, Jennifer Palomo, Cem Gabay, Praxedis Martin, Christian Alexander Seemayer
Publikováno v:
Journal of Immunology, Vol. 198, No 7 (2017) pp. 2916-2926
Journal of immunology (Baltimore Md. : 1950)
Journal of immunology (Baltimore Md. : 1950)
The biological activity of IL-1 is tightly regulated by the specific receptor antagonist (IL-1Ra) and the decoy receptor IL-1 receptor type 2 (IL-1R2). The role of IL-1Ra has been well demonstrated in IL-1Ra–deficient mice. In contrast, the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76149d38e9e8f2d83e0a16240b73ede
https://archive-ouverte.unige.ch/unige:110653
https://archive-ouverte.unige.ch/unige:110653