Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pravinchandra J. Vankawala"'
Autor:
Naveenkumar Kolla, Chandrashekar R. Elati, Pravinchandra J. Vankawala, Srinivas Gangula, Eswaraiah Sajja, Yerremilli Anjaneyulu, Apurba Bhattacharya, Venkataraman Sundaram, Vijayavitthal T. Mathad
Publikováno v:
CHIMIA, Vol 60, Iss 9 (2006)
The development of a large-scale synthesis for (1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butan-1-amine (S-(+)-1), a key intermediate of repaglinide (2), is described. The process conditions for S-(+)-1 involving nucleophilic substitution, Grignard rea
Externí odkaz:
https://doaj.org/article/7a74b464ce584d1d93f5c6f00548117f
Autor:
Raghavendra K. Panchangam, Navnath Chintaman Niphade, Sharad Subhash Ippar, Gorakshanath Balasaheb Shinde, Pravinchandra J. Vankawala, Vijayavitthal T. Mathad
Publikováno v:
Synthetic Communications. 41:341-346
An efficient synthesis of 1-(naphthalen-1-yl)ethanamine ( RS -2) and its practical resolution to optically pure (1R)-(naphthalen-1-yl)ethanamine ( R -(+)-2), a key intermediate in the synthesis of cinacalcet hydrochloride (1), is described. The resol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ef6c9f14ed456c079d1a4c1a7fb8afe
https://doi.org/10.1080/00397910903538651
https://doi.org/10.1080/00397910903538651
Autor:
Navanath C. Niphade, Pravinchandra J. Vankawala, Vijayavitthal T. Mathad, Anil C. Mali, Ramesh Chandra Ojha, Kunal M. Jagtap
Publikováno v:
Organic Process Research & Development. 12:731-735
A simple, efficient and highly economic process for the production of donepezil hydrochloride (1), an anti-Alzheimer drug is reported. The process relies upon improved and large-scale synthesis of a key intermediate: 1-benzylpiperidine-4-carboxaldehy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d6d343cdd1a3bf8ef780028d0e9414e
https://doi.org/10.1021/op800066m
https://doi.org/10.1021/op800066m
Autor:
Vijayavitthal T. Mathad, Venkatraman Sundaram, Apurba Bhattacharya, Muttu L. Avinigiri, Subrahmanyeswararao Chalamala, Pravinchandra J. Vankawala, Rakeshwar Bandichhor, Naveenkumar Kolla, Anitha Naredla, Chandrashekar R. Elati, Srinivas Gangula
Publikováno v:
Tetrahedron Letters. 48:8001-8004
A simple and convergent approach to enantiomerically pure 5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one 1, a potent orally active antagonist of the human neurokinin-1 (NK-1) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e83463e2bb6792e4686e56572d6c18b0
https://doi.org/10.1016/j.tetlet.2007.09.051
https://doi.org/10.1016/j.tetlet.2007.09.051
Autor:
Sundaram Venkatraman, Yerrimilli Anjaneyulu, M. Sreenivasulu, Vijayavitthal T. Mathad, Naveenkumar Kolla, Pravinchandra J. Vankawala, Apurba Bhattacharya, K. Arun Kumar, Chandrashekar R. Elati
Publikováno v:
Synthetic Communications. 37:3439-3446
Enzyme‐catalyzed efficient synthesis of (1R)‐[3,5‐bis (trifluoromethyl) phenyl] ethanol (R)‐(3), a key intermediate for aprepitant, via enantioselective transesterification of racemic 1‐[3,5‐bis (trifluoromethyl) phenyl] ethanol (RS)‐3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a979b4e5b294d7e503edf07fd1253a1
https://doi.org/10.1080/00397910701487473
https://doi.org/10.1080/00397910701487473
Autor:
Subrahmanyeswarara Chalamala, Pravinchandra J. Vankawala, Venkatraman Sundaram, Naveenkumar Kolla, Vijayavitthal T. Mathad, Chandrashekar R. Elati, Srinivas Gangula, Himabindu Vurimidi, Apurba Bhattacharya
Publikováno v:
Organic Process Research & Development. 11:289-292
Research work presented here describes an approach to achieve the enantiopure escitalopram (1) via didesmethyl escitalopram (4), which is easily resolvable compared to citalopram (1a) through diastereomeric salt crystallization. The resolved intermed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ef6789917244b73d23b75ead4b0a5f
https://doi.org/10.1021/op060175e
https://doi.org/10.1021/op060175e
Autor:
Subrahmanyeswara Rao Chalamala, Vijayavitthal T. Mathad, Venkataraman Sundaram, Himabindu Vurimidi, Chandrashekar R. Elati, Naveenkumar Kolla, Pravinchandra J. Vankawala
Publikováno v:
Synthetic Communications. 36:169-174
A new, economical, and efficient process has been developed for large‐scale synthesis of donepezil 1, an anti‐Alzheimer's drug. The process involves palladium‐catalyzed hydrogenation of (2E)‐5,6‐di...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b48f6701d5fe5409762224aedefba85b
https://doi.org/10.1080/00397910500334231
https://doi.org/10.1080/00397910500334231
Autor:
Pravinchandra J. Vankawala, Vijayavitthal T. Mathad, Naveenkumar Kolla, Chandrashekar R. Elati, Srinivas Gangula, Yerremilli Anjaneyulu, Muthulingam Arunagiri, Sundaram Venkatraman, Apurba Bhattacharya
Publikováno v:
Organic Process Research & Development. 11:455-457
An efficient and alternative synthesis of enantiomerically pure (3S)-4-benzyl-3-(4-fluorophenyl)morpholin-2-one (S)-(+)-2), a key intermediate in the synthesis aprepitant (1), is described. The key resolution of N-benzylglycinamide, (±)-9, is achiev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f995ac87a6653b4733e44bea2be3dc25
https://doi.org/10.1021/op700030d
https://doi.org/10.1021/op700030d
Autor:
Navnath Chintaman Niphade, Sharad Subhash Ippar, Gorakshanath Balasaheb Shinde, Raghavendra K. Panchangam, Pravinchandra J. Vankawala, Vijayavitthal T. Mathad
Publikováno v:
ChemInform. 42
A synthesis suitable for large-scale production is given for the hydrochloride salt of (R)-1-(naphthalen-1-yl)ethanamine (V), which is a key intermediate in the synthesis cinacalcet hydrochloride, a drug for the treatment of secondary hyperparathyroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5fa0d77cceb98a2ca268e0fb8ef8126
https://doi.org/10.1002/chin.201128084
https://doi.org/10.1002/chin.201128084
Autor:
Chandrashekar R. Elati, Yerrimilli Anjaneyulu, Pravinchandra J. Vankawala, Sundaram Venkatraman, Vijayavitthal T. Mathad, Apurba Bhattacharya, K. Arun Kumar, M. Sreenivasulu, Naveenkumar Kolla
Publikováno v:
ChemInform. 39
Enzyme‐catalyzed efficient synthesis of (1R)‐[3,5‐bis (trifluoromethyl) phenyl] ethanol (R)‐(3), a key intermediate for aprepitant, via enantioselective transesterification of racemic 1‐[3,5‐bis (trifluoromethyl) phenyl] ethanol (RS)‐3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e0845bb5d696c46d33e7263900868bd
https://doi.org/10.1002/chin.200810073
https://doi.org/10.1002/chin.200810073