Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Pravi Moodley"'
Autor:
Tamlyn A. Rautenberg, Shu Kay Ng, Gavin George, Mahomed-Yunus S. Moosa, Suzanne M. McCluskey, Rebecca F. Gilbert, Selvan Pillay, Isaac Aturinda, Kevin L. Ard, Winnie R. Muyindike, Nicholas Musinguzi, Godfrey Masette, Melendhran Pillay, Pravi Moodley, Jaysingh Brijkumar, Rajesh T. Gandhi, Brent Johnson, Henry Sunpath, Mwebesa B. Bwana, Vincent C. Marconi, Mark J. Siedner
Publikováno v:
Health and Quality of Life Outcomes, Vol 21, Iss 1, Pp 1-8 (2023)
Abstract Background Antiretroviral treatment improves health related quality of life (HRQoL) of people with human immunodeficiency virus (PWH). However, one third initiating first-line treatment experience virological failure and the determinants of
Externí odkaz:
https://doaj.org/article/d2b188a0d0b546e59e050e2059d1f1ea
Autor:
Lilishia Gounder, Andrew Tomita, Richard Lessells, Sandrini Moodley, Kerri-Lee Francois, Aabida Khan, Melendhran Pillay, Sontaga C Manyana, Subitha Govender, Kerusha Govender, Pravi Moodley, Raveen Parboosing, Nokukhanya Msomi, Frank Tanser, Kogieleum Naidoo, Benjamin Chimukangara
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 5, p e0003224 (2024)
South Africa rolled out dolutegravir (DTG) as first-line antiretroviral therapy (ART) in December 2019 to overcome high rates of pretreatment non-nucleoside reverse transcriptase inhibitor drug resistance. In the context of transition to DTG-based AR
Externí odkaz:
https://doaj.org/article/d67f1eec97dc4715a89305e9d69f3aa4
Autor:
Sontaga Manyana, Melendhran Pillay, Lilishia Gounder, Aabida Khan, Pravi Moodley, Kogieleum Naidoo, Benjamin Chimukangara
Publikováno v:
AIDS Research and Therapy, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background As use of dolutegravir (DTG) becomes more common in resource limited settings (RLS), the demand for integrase resistance testing is increasing. Affordable methods for genotyping all relevant HIV-1 pol genes (i.e., protease (PR), r
Externí odkaz:
https://doaj.org/article/c4e8e08238a9408b8eb06dda5410cd9f
Autor:
Jienchi Dorward, Richard Lessells, Katya Govender, Pravi Moodley, Natasha Samsunder, Yukteshwar Sookrajh, Phil Turner, Christopher C. Butler, Gail Hayward, Monica Gandhi, Paul K. Drain, Nigel Garrett
Publikováno v:
Journal of the International AIDS Society, Vol 26, Iss 9, Pp n/a-n/a (2023)
Abstract Introduction Novel point‐of‐care assays which measure urine tenofovir (TFV) concentrations may have a role in improving adherence monitoring for people living with HIV (PLHIV) receiving antiretroviral therapy (ART). However, further stud
Externí odkaz:
https://doaj.org/article/139fbfddd3f64d919c447d4a998b16ba
Autor:
Kerri-Lee A. Francois, Nokukhanya Msomi, Kerusha Govender, Lilishia Gounder, Pravi Moodley, Raveen Parboosing, Indrani Chetty, Lunga Xaba, Aabida Khan
Publikováno v:
African Journal of Laboratory Medicine, Vol 12, Iss 1, Pp e1-e6 (2023)
Background: KwaZulu-Natal ranked second highest among South African provinces for the number of laboratory-confirmed cases during the second wave of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The seroprevalence of SARS
Externí odkaz:
https://doaj.org/article/136ecb808a7249219fc9b41ef7e7d8bf
Autor:
Benjamin Chimukangara, Richard J. Lessells, Benn Sartorius, Lilishia Gounder, Sontaga Manyana, Melendhran Pillay, Lavanya Singh, Jennifer Giandhari, Kerusha Govender, Reshmi Samuel, Nokukhanya Msomi, Kogieleum Naidoo, Tulio de Oliveira, Pravi Moodley, Raveen Parboosing
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 29, Iss , Pp 468-475 (2022)
ABSTRACT: Objectives: In low–middle-income countries, increasing levels of HIV drug resistance (HIVDR) on second-line protease inhibitor (PI)-based regimens are a cause for concern given the limited drug options for third-line antiretroviral therap
Externí odkaz:
https://doaj.org/article/06c595bd500c4b65a557b119ab107495
Autor:
Benjamin Chimukangara, Richard J. Lessells, Lavanya Singh, Indra Grigalionyte, Nonhlanhla Yende-Zuma, Rochelle Adams, Halima Dawood, Linda Dlamini, Sibonisile Buthelezi, Sheldon Chetty, Karidia Diallo, Wayne A. Duffus, Mary Mogashoa, Melissa B. Hagen, Jennifer Giandhari, Tulio de Oliveira, Pravi Moodley, Nesri Padayatchi, Kogieleum Naidoo
Publikováno v:
AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-8 (2021)
Abstract Background Introduction of tenofovir (TDF) plus lamivudine (3TC) and dolutegravir (DTG) in first- and second-line HIV treatment regimens in South Africa warrants characterization of acquired HIV-1 drug resistance (ADR) mutations that could i
Externí odkaz:
https://doaj.org/article/4feda9c4b87248578ba0f4027fb7d5c7
Autor:
Monica Gandhi, Kogieleum Naidoo, Nigel Garrett, Jienchi Dorward, Hope Ngobese, Katherine Thomas, Salim Abdool Karim, Connie Celum, Tim R Cressey, Paul K Drain, Monisha Sharma, Yukteshwar Sookrajh, Richard Lessells, Fathima Sayed, Justice Quame-Amaglo, Nivashnee Naicker, Ashley R Bardon, Cheryl Pillay, Erika Feutz, Jane M Simoni, Pravi Moodley
Publikováno v:
BMJ Open, Vol 11, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/3cc5c596b16a4a9eadd1db9e32f85f66
Autor:
Chang Liu, Zicheng Wang, Qin Hui, Yiyun Chiang, Junyu Chen, Jaysingh Brijkumar, Johnathan A. Edwards, Claudia E. Ordonez, Mathew R. Dudgeon, Henry Sunpath, Selvan Pillay, Pravi Moodley, Daniel R. Kuritzkes, Mohamed Y. S. Moosa, Dean P. Jones, Vincent C. Marconi, Yan V. Sun
Publikováno v:
Metabolites, Vol 12, Iss 7, p 624 (2022)
Genome-wide association studies (GWAS) of circulating metabolites have revealed the role of genetic regulation on the human metabolome. Most previous investigations focused on European ancestry, and few studies have been conducted among populations o
Externí odkaz:
https://doaj.org/article/bf1d74c523884a97babc8a57fa42f3ec
Autor:
Salim Allana, Elena Shashkina, Barun Mathema, Nino Bablishvili, Nestani Tukvadze, N. Sarita Shah, Russell R. Kempker, Henry M. Blumberg, Pravi Moodley, Koleka Mlisana, James C.M. Brust, Neel R. Gandhi
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 3, Pp 491-495 (2017)
Although pyrazinamide is commonly used for tuberculosis treatment, drug-susceptibility testing is not routinely available. We found polymorphisms in the pncA gene for 70% of multidrug-resistant and 96% of extensively drug-resistant Mycobacterium tube
Externí odkaz:
https://doaj.org/article/43caa085ff914e1bacf2af7b4b7464af