Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Praveen Varma Manthena"'
Autor:
Rahul Saxena, Soumendrakrishna Karmahapatra, Krishna Kiran Kota, Gargi Roy, Rabindra Roy, Aykut Üren, Praveen Varma Manthena, Sanjay Adhikari
Publikováno v:
Molecular and Cellular Biochemistry. 362:195-201
Mammalian apurinic/apyrimidinic endonuclease (APE1) initiates the repair of abasic sites (AP-sites), which are highly toxic, mutagenic, and implicated in carcinogenesis. Also, reducing the activity of APE1 protein in cancer cells and tumors sensitize
Autor:
Partha S. Mitra, Raja Mazumder, Pooja Khatkar, Nikhil Nuthalapati, Soumendra K. Karmahapatra, Monica Dixon, Mahandranauth A. Chetram, Sanjay Adhikari, Suhani Gupta, Jordan Woodrick, Christopher A. Loffredo, Praveen Varma Manthena, Aykut Üren, Sivanesan Dakshanamurthy, Ganga Narasimhan, Rabindra Roy
Human N-methylpurine DNA glycosylase (hMPG) initiates base excision repair of a number of structurally diverse purine bases including 1,N(6)-ethenoadenine, hypoxanthine, and alkylation adducts in DNA. Genetic studies discovered at least eight validat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900c07e96472f2f42d006cbcf16e38c5
https://europepmc.org/articles/PMC4335234/
https://europepmc.org/articles/PMC4335234/
Autor:
Eric Glasgow, Stephen W. Byers, Soumendra K. Karmahapatra, Sanjay Adhikari, Tejaswita M. Karve, Aykut Üren, Sanjona Bandyopadhyay, Praveen Varma Manthena, Jordan Woodrick, Tapas Saha
Publikováno v:
BMC Research Notes, Vol 5, Iss 1, p 134 (2012)
BMC Research Notes
BMC Research Notes
Background Topo-poisons can produce an enzyme-DNA complex linked by a 3'- or 5'-phosphotyrosyl covalent bond. 3'-phosphotyrosyl bonds can be repaired by tyrosyl DNA phosphodiesterase-1 (TDP1), an enzyme known for years, but a complementary human enzy
Publikováno v:
Analytical biochemistry. 400(2)
Protein purification is still very empirical, and a unified method for purifying proteins without an affinity tag is not available yet. In the postgenomic era, functional genomics, however, strongly demands such a method. In this paper we have formul
N -Methylpurine-DNA glycosylase (MPG), a ubiquitous DNA repair enzyme, initiates excision repair of several N -alkylpurine adducts, deaminated and lipid peroxidation-induced purine adducts. MPG from human and mouse has previously been cloned and expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21344f93168d3b0f6620ce78db63d9a6
https://europepmc.org/articles/PMC2702510/
https://europepmc.org/articles/PMC2702510/