Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Praveen Koganti"'
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1250 (2024)
Repeating sequences of DNA, or repetitive elements (REs), are common features across both prokaryotic and eukaryotic genomes. Unlike many of their protein-coding counterparts, the functions of REs in host cells remained largely unknown and have often
Externí odkaz:
https://doaj.org/article/6bff7bb5bcf3415d821a9bc681857637
Autor:
Michael Blank, Gal Levy-Cohen, Praveen Koganti, Dhanoop Manikoth Ayyathan, Pooja A. Shah, Liat Apel-Sarid, Aurora P. Borroni, Andrea Emanuelli
DNA topoisomerase IIα (Topo IIα) ensures genomic integrity and unaltered chromosome inheritance and serves as a major target of several anticancer drugs. Topo IIα function is well understood, but how its expression is regulated remains unclear. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20cf7649fa08709eed04b95fa460d440
https://doi.org/10.1158/0008-5472.c.6508881.v1
https://doi.org/10.1158/0008-5472.c.6508881.v1
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Protein ubiquitination is an evolutionary conserved highly-orchestrated enzymatic cascade essential for normal cellular functions and homeostasis maintenance. This pathway relies on a defined set of cellular enzymes, among them, substrate-specific E3
Externí odkaz:
https://doaj.org/article/7edb2ba1929a4f2f8fe6bd341656dbae
Publikováno v:
Critical reviews in oncogenesis. 27(1)
Androgen deprivation therapy (ADT) that antagonizes androgen receptor (AR) signaling has made significant increases to overall survival of prostate cancer patients. However, ADT is not curative, and patients eventually progress to castration resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cfa9f6dd26085e3d2b64e84e04962a
https://pubmed.ncbi.nlm.nih.gov/35993978
https://pubmed.ncbi.nlm.nih.gov/35993978
Autor:
Praveen, Koganti, Saxena, Nandita
Publikováno v:
Radiation Research, 2013 Jun 01. 179(6), 725-736.
Externí odkaz:
http://dx.doi.org/10.1667/RR3189.1
Autor:
Praveen Koganti, Venkata Narasimha Kadali, Dhanoop Manikoth Ayyathan, Andrea Emanuelli, Biagio Paolini, Gal Levy-Cohen, Michael Blank
Publikováno v:
Cellular and Molecular Life Sciences. 79
Epitranscriptomic changes in RNA catalyzed by the RNA-editing enzyme ADAR1 play an essential role in the regulation of diverse molecular and cellular processes, both under physiological conditions and in disease states, including cancer. Yet, despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86414d3ba429acbc663b741f1dcd228f
https://doi.org/10.1007/s00018-022-04272-8
https://doi.org/10.1007/s00018-022-04272-8
Autor:
Praveen Koganti, Andrea Emanuelli, Michael B. Blank, Dhanoop Manikoth Ayyathan, Liat Apel-Sarid, Talia Litmanovitch, Victoria Marcu-Malina, Luba Trakhtenbrot
Publikováno v:
Oncogene. 39(16)
E3 ubiquitin ligases (E3s) play essential roles in the maintenance of tissue homeostasis under normal and stress conditions, as well as in disease states, particularly in cancer. However, the role of E3s in the initiation of human tumors is poorly un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e1e7c3570952b3e61a789ebd4536c9
https://pubmed.ncbi.nlm.nih.gov/32103168
https://pubmed.ncbi.nlm.nih.gov/32103168
Autor:
Michael B. Blank, Dhanoop Manikoth Ayyathan, Pooja Anil Shah, Praveen Koganti, Biagio Paolini, Milana Frenkel-Morgenstern, Andrea Emanuelli, Rajesh Detroja, Liat Apel-Sarid
Publikováno v:
Cancers, Vol 11, Iss 4, p 556 (2019)
Cancers
Volume 11
Issue 4
Cancers
Volume 11
Issue 4
SMURF2, an E3 ubiquitin ligase and suggested tumor suppressor, operates in normal cells to prevent genomic instability and carcinogenesis. However, the mechanisms underlying SMURF2 inactivation in human malignancies remain elusive, as SMURF2 is rarel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582a560f3b4e4b820ce0b6ed24da23f2
https://www.mdpi.com/2072-6694/11/4/556
https://www.mdpi.com/2072-6694/11/4/556
Autor:
Praveen Koganti, Rajkumar Tulsawani, Kshipra Misra, Purva Sharma, Manish Sharma, Shivani Arora
Publikováno v:
International journal of medicinal mushrooms. 20(5)
Ganoderma lucidum is known to exert many health benefits including effects to improve oxygen utilization. Therefore, this study was designed to evaluate the role of a hydroalcoholic G. lucidum extract in providing tolerance to HT22 cells grown under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59619b1d114e5950c0d598c41136112d
https://pubmed.ncbi.nlm.nih.gov/29953358
https://pubmed.ncbi.nlm.nih.gov/29953358
Autor:
Liat Apel-Sarid, Praveen Koganti, Gal Levy-Cohen, Nataša Ilić, Aurora Paola Borroni, Michael B. Blank, Pooja Anil Shah, Andrea Emanuelli, Biagio Paolini, Dhanoop Manikoth Ayyathan
Publikováno v:
Aging Cell
Summary A‐lamins, encoded by the LMNA gene, are major structural components of the nuclear lamina coordinating essential cellular processes. Mutations in the LMNA gene and/or alterations in its expression levels have been linked to a distinct subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a27d9a099dd159f42d05e8779e1daa
https://pubmed.ncbi.nlm.nih.gov/29405587
https://pubmed.ncbi.nlm.nih.gov/29405587