Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Praveen K. Vayalil"'
Autor:
M. Ryan Smith, Praveen K. Vayalil, Fen Zhou, Gloria A. Benavides, Reena R. Beggs, Hafez Golzarian, Bhavitavya Nijampatnam, Patsy G. Oliver, Robin A.J. Smith, Michael P. Murphy, Sadanandan E. Velu, Aimee Landar
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 136-148 (2016)
Many cancer cells follow an aberrant metabolic program to maintain energy for rapid cell proliferation. Metabolic reprogramming often involves the upregulation of glutaminolysis to generate reducing equivalents for the electron transport chain and am
Externí odkaz:
https://doaj.org/article/28598c4d4dc14203b4dba36a2bf4aa84
Autor:
Praveen K Vayalil, Joo-Yeun Oh, Fen Zhou, Anne R Diers, M Ryan Smith, Hafez Golzarian, Patsy G Oliver, Robin A J Smith, Michael P Murphy, Sadanandan E Velu, Aimee Landar
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120460 (2015)
Despite advances in screening and treatment over the past several years, breast cancer remains a leading cause of cancer-related death among women in the United States. A major goal in breast cancer treatment is to develop safe and clinically useful
Externí odkaz:
https://doaj.org/article/12e59c8641af42228ba786a8797bd8f0
Autor:
Praveen K. Vayalil
Publikováno v:
Oncology Letters.
Mitochondria are emerging as key players in the tumorigenic process of cells by maintaining the biosynthetic and energetic capabilities of cancer cells. It is now evident that mitochondria are involved in the malignant transformation, cell proliferat
Autor:
Praveen K. Vayalil, Aimee Landar
Publikováno v:
Oncotarget
// Praveen K. Vayalil 1 , Aimee Landar 1 1 Department of Pathology, Division of Molecular and Cellular Pathology, Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA Correspondence to: Praveen K. Vayalil, e-
Autor:
Rajeev S. Samant, William P. Jackson, Jack W. Rostas, Praveen K. Vayalil, Mateus Mota, Sarah K. Bailey, Lalita A. Shevde, Aimee Landar, Madhuri S. Mulekar
Publikováno v:
Carcinogenesis. 39(9)
The NF2 gene encodes the tumor and metastasis suppressor protein Merlin. Merlin exerts its tumor suppressive role by inhibiting proliferation and inducing contact-growth inhibition and apoptosis. In the current investigation, we determined that loss
Autor:
Joo-Yeun Oh, M. Ryan Smith, Praveen K. Vayalil, Fen Zhou, Karina C. Ricart, Stephanie B. Wall, Aimee Landar
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1840:913-922
Background Redox signaling is an important emerging mechanism of cellular function. Dysfunctional redox signaling is increasingly implicated in numerous pathologies, including atherosclerosis, diabetes, and cancer. The molecular messengers in this ty
Autor:
Praveen K. Vayalil
Publikováno v:
Critical Reviews in Food Science and Nutrition. 52:249-271
Date palm is one of the oldest trees cultivated by man. In the folk-lore, date fruits have been ascribed to have many medicinal properties when consumed either alone or in combination with other herbs. Although, fruit of the date palm served as the s
Therapeutic Value of Small Molecule Inhibitor to Plasminogen Activator Inhibitor–1 for Lung Fibrosis
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Fibrosis is a final stage of many lung diseases, with no effective treatment. Plasminogen activator inhibitor-1 (PAI-1), a primary inhibitor of tissue-type and urokinase-type plasminogen activators (tPA and uPA, respectively), plays a critical role i
Autor:
Harshith P. Bhat, Manjeshwar Shrinath Baliga, Praveen K. Vayalil, Bantwal Raghavendra Vittaldas Baliga, Shaun M. Kandathil
Publikováno v:
Food Research International. 44:1812-1822
Phoenix dactylifera L., commonly known as the date palm is a primeval plant and has been cultivated for its edible fruit in the desert oasis of the Arab world for centuries. The fruits are a rich source of carbohydrates, dietary fibers, certain essen
Autor:
Praveen K. Vayalil, Ae-Kyung Yi, Edward M. Postlethwait, Karen E. Iles, Rui-Ming Liu, Jinah Choi
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 293:L1281-L1292
Transforming growth factor (TGF)-beta upregulates plasminogen activator inhibitor type 1 (PAI-1) in a variety of cell types, and PAI-1 is considered to be an essential factor for the development of fibrosis. Our previous studies demonstrated that TGF