Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Praveen Barrodia"'
Autor:
Huihui Fan, Feng Wang, Andy Zeng, Alex Murison, Katarzyna Tomczak, Dapeng Hao, Fatima Zahra Jelloul, Bofei Wang, Praveen Barrodia, Shaoheng Liang, Ken Chen, Linghua Wang, Zhongming Zhao, Kunal Rai, Abhinav K. Jain, John Dick, Naval Daver, Andy Futreal, Hussein A. Abbas
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Acute myeloid leukemia (AML) is a heterogeneous disease characterized by high rate of therapy resistance. Since the cell of origin can impact response to therapy, it is crucial to understand the lineage composition of AML cells at time of th
Externí odkaz:
https://doaj.org/article/6eb3f414ffc54fbebd35ea949259c4ec
Autor:
Hussein A. Abbas, Dapeng Hao, Katarzyna Tomczak, Praveen Barrodia, Jin Seon Im, Patrick K. Reville, Zoe Alaniz, Wei Wang, Ruiping Wang, Feng Wang, Gheath Al-Atrash, Koichi Takahashi, Jing Ning, Maomao Ding, Hannah C. Beird, Jairo T. Mathews, Latasha Little, Jianhua Zhang, Sreyashi Basu, Marina Konopleva, Mario L. Marques-Piubelli, Luisa M. Solis, Edwin Roger Parra, Wei Lu, Auriole Tamegnon, Guillermo Garcia-Manero, Michael R. Green, Padmanee Sharma, James P. Allison, Steven M. Kornblau, Kunal Rai, Linghua Wang, Naval Daver, Andrew Futreal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The response rate of relapsed/refractory acute myeloid leukemia patients to PD-1 checkpoint blockade is low and unpredictable. Authors here show by single cell RNA sequencing, T cell receptor profiling and genomic analysis that the phenotypes and rep
Externí odkaz:
https://doaj.org/article/28224d44710d40fe8758d8643917f98e
Publikováno v:
Cells, Vol 12, Iss 3, p 365 (2023)
Immunotherapy has brought new hope for cancer patients in recent times. However, despite the promising success of immunotherapy, there is still a need to address major challenges including heterogeneity in response among patients, the reoccurrence of
Externí odkaz:
https://doaj.org/article/b07324bb4ffb40eab0421b8c0537f1a7
Publikováno v:
Cell & Bioscience, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Background The blood filtering organ in zebrafish embryos is the pronephros, which consists of two functional nephrons. Segmentation of a nephron into different domains is essential for its function and is well conserved among vertebrates. Z
Externí odkaz:
https://doaj.org/article/f83e50788ea54f9f90de31cac71b7602
Autor:
Feng Wang, Wei Wang, Michael Green, Ruiping Wang, Jianhua Zhang, Andrew Futreal, Jing Ning, James Allison, Padmanee Sharma, Marina Konopleva, Latasha Little, Hussein Abbas, Katarzyna Tomczak, Praveen Barrodia, Jin Seon Im, Patrick Reville, Zoe Alaniz, Gheath Al-Atrash, Koichi Takahashi, Maomao Ding, Jairo Matthews, Sreyashi Basu, Guillermo Garcia-Manero, Steven Kornblau, Kunal Rai, Naval Daver
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/01c9173f79124520a0e23fa07c19006c
Autor:
Jiah Yang, Anand K Singh, Ming Tang, Moran Amit, Kunal Rai, Praveen Barrodia, Margarita Divenko, Shan Jiang, S. Carson Callahan, Jonathan Schulz, Nazanin Esmaeili Anvar, Emre Arslan, Zhiyi Liu, Tongxin Xie, Jeffrey N. Myers
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, with 5-year survival of ∼50%. Genomic profiling studies have identified important somatic mutations in this disease which presents an opportunity for precision
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78701ee0b0ea75b2663cfaa25ff797fe
https://doi.org/10.1101/2021.09.21.461314
https://doi.org/10.1101/2021.09.21.461314
Autor:
Ruiping Wang, Zoe Alaniz, Praveen Barrodia, Courtney D. DiNardo, Guillermo Garcia-Manero, Latasha Little, Michael R. Green, Koichi Takahashi, Gheath Alatrash, Wei Wang, Dapeng Hao, P. Andrew Futreal, Jairo Matthews, Jin S. Im, Farhad Ravandi, Steven M. Kornblau, Kunal Rai, Feng Wang, Maomao Ding, Linghua Wang, Jing Ning, Jianhua Zhang, Gautam Borthakur, Patrick K. Reville, James P. Allison, Naval Daver, Padmanee Sharma, Hussein A. Abbas, Marina Konopleva, Katarzyna Tomczak, Tapan M. Kadia, Sreyashi Basu
Publikováno v:
Blood. 136:29-31
Background The success of allogenic stem cell transplantation in curing AML suggests that the immune system can be harnessed to eradicate AML. In a phase 2 trial (NCT02397720) in relapsed/refractory (R/R) AML patients, we demonstrated that the azacit
Publikováno v:
Cell & Bioscience, Vol 8, Iss 1, Pp 1-15 (2018)
Cell & Bioscience
Cell & Bioscience
Background The blood filtering organ in zebrafish embryos is the pronephros, which consists of two functional nephrons. Segmentation of a nephron into different domains is essential for its function and is well conserved among vertebrates. Zebrafish
Autor:
Guillermo Garcia-Manero, Dapeng Hao, Edwin R. Parra, Jairo T. Mathews, Naval Daver, Patrick K. Reville, Padmanee Sharma, Auriole Tamegnon, Latasha Little, Koichi Takahashi, Kunal Rai, Jin Seon Im, Feng Wang, Hussein A. Abbas, Wei Wang, Luisa M. Solis, Maomao Ding, Sreyashi Basu, Michael R. Green, Marina Konopleva, James P. Allison, Katarzyna Tomczak, Zoe Alaniz, Gheath Alatrash, Jing Ning, Wei Lu, Mario L. Marques-Piubelli, Andrew Futreal, Steven M. Kornblau, Hannah C. Beird, Praveen Barrodia, Ruiping Wang, Linghua Wang, Jianhua Zhang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
In contrast to the curative effect of allogenic stem cell transplantation in acute myeloid leukemia via T cell activity, only modest responses are achieved with checkpoint-blockade therapy, which might be explained by T cell phenotypes and T cell rec
Autor:
Kunal Rai, Jairo Matthews, Linghua Wang, Naval Daver, Zoe Alaniz, Feng Wang, Katarzyna Tomczak, Guillermo Garcia-Manero, Jianhua Zhang, Jin Seon Im, Padmanee Sharma, Gheath Alatrash, Maomao Ding, Jing Ning, Praveen Barrodia, Dapeng Hao, Latasha Little, Koichi Takahashi, Ruiping Wang, Wei Wang, Sreyashi Basu, Patrick K. Reville, Hussein A. Abbas, James P. Allison, Marina Konopleva, Steven M. Kornblau, Michael R. Green, Andrew Futreal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Allogeneic stem cell transplantation can cure relapsed/refractor (R/R) AML via grafted T cells versus leukemia effect, but not a viable option to many patients. By combining azacitidine with nivolumab, we harnessed T cell activity and demo