Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Pravda Quinones"'
Autor:
Gina M. Morgan, Mark S. Schmidt, Haider Mehdi, Jared M. McLendon, Ryan L. Boudreau, Alexander M. Greiner, Pravda Quinones, Jin-Young Yoon, Daniel S. Matasic, Barry London, Charles Brenner, Kaikobad Irani
Publikováno v:
J Mol Cell Cardiol
RationaleThe cardiac sodium channel NaV1.5, encoded by SCN5A, produces the rapidly inactivating depolarizing current INa that is responsible for the initiation and propagation of the cardiac action potential. Acquired and inherited dysfunction of NaV
Publikováno v:
Circulation Research. 125
Background: Boosting NAD + content within the heart has emerged as a cardioprotective strategy against heart failure-related remodeling, ischemic injury, and arrhythmias. Our group recently demonstrated that the bioavailable NAD + precursor Nicotinam